Researcher
Jan Van Den Abbeele
- Keywords:tsetse fly, trypanosome transmission, innate immunity, salivary gland proteins, bacterial symbionts, paratransgenesis, B361-physiology-of-invertebrates, Animal African trypanosomiasis, Trypanosoma congolense, Trypanosoma vivax, drug resistance, genetic diversity, evolution and transmission dynamics, B750-veterinary-medicine, Human African trypanosomiasis, Trypanosoma brucei, host innate immunity, B780-tropical-medicine
Affiliations
- Trypanosoma (Research unit)
Member
From20 Mar 2021 → Today - Veterinary Protozoology (Research unit)
Member
From1 Apr 2010 → 19 Mar 2021
Projects
1 - 10 of 12
- Development and integration of serological and molecular diagnostics in view of interruption of transmission of gambiense-HATFrom1 Dec 2022 → Today
- Innate immune response in the mammalian host skin after the bite of a trypanosome-infected tsetse flyFrom1 Jan 2022 → Today
- Strengthen research and education capacities in the partner institutes (INRB, CRSK, ESP) in DRC (Outcome 1) - Support to interruption of transmission of Human African Trypanosomiasis (HAT) by 2030 (Outcome 2)From1 Jan 2022 → Today
- Novel genetic tools to study the molecular basis of drug resistance in Trypanosoma congolenseFrom1 Oct 2018 → 31 Dec 2020
- The RNA editing space of the neglected genome in the major livestock African trypanosome parasite, Trypanosoma congolense.From1 Nov 2017 → 31 Dec 2018
- Kinetoplast genomics for the fine-scale study of hybrid zones in eukaryote parasitesFrom1 Jan 2017 → 30 Jun 2020
- African trypanosome transmission: unraveling the molecular 'tripartite' between a protozoan parasite, a symbiotic bacterium and the tsetse fly innate immunityFrom1 Jul 2013 → 31 Dec 2018
- Tolerance and resistance to parasite infection: trypanosomatidae as paradigmFrom1 Apr 2012 → 31 Dec 2017
- Implementation and coordination of a regional training programmeFrom1 Mar 2012 → 31 Oct 2020
- Trypanosoom-bindende eiwitten in het tseetseevliegspeeksel bevorderen de overdracht van deze parasietFrom1 Jan 2012 → 31 Dec 2017
Publications
1 - 10 of 63
- A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission(2022)
Authors: Sabine Bachmaier, Giacomo Giacomelli, Estefania Calvo-Alvarez, Larissa Rezende Vieira, Jan Van Den Abbeele, Aris Aristodemou, Esben Lorentzen, Matthew Gould, Ana Brennand, Jean-Wiliam Dupuy, et al.
Pages: 5445 - Prevalence of Trypanosoma and Sodalis in wild populations of tsetse flies and their impact on sterile insect technique programmes for tsetse eradication(2022)
Authors: Mouhamadou M Dieng, Kiswend-Sida M Dera, Percy Moyaba, Gisele M S Ouedraogo, Guler Demirbas-Uzel, Fabian Gstöttenmayer, Fernando Chanisso Mulandane, Luis Neves, Sihle Mdluli, Jean-Baptiste Rayaisse, et al.
Pages: 3322 - Targeting the tsetse-trypanosome interplay using genetically engineered Sodalis glossinidius(2022)
Authors: Linda De Vooght, Karina De Ridder, Shahid Hussain, Benoît Stijlemans, Patrick De Baetselier, Guy Caljon, Jan Van Den Abbeele
- Heme-deficient metabolism and impaired cellular differentiation as an evolutionary trade-off for human infectivity in Trypanosoma brucei gambiense(2022)
Authors: Eva Horáková, Laurence Lecordier, Paula Cunha, Roman Sobotka, Piya Changmai, Catharina J. M. Langedijk, Jan Van Den Abbeele, Benoit Vanhollebeke, Julius Lukes
Pages: 7075 - Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes(2021)
Authors: Radoslaw P. Kozak, Karina Mondragon-Shem, Christopher Williams, Clair Rose, Samirah Perally, Guy Caljon, Jan Van Den Abbeele, Katherine Wongtrakul-Kish, Richard A. Gardner, Daniel Spencer, et al.
- Evaluation of the relative roles of the Tabanidae and Glossinidae in the transmission of trypanosomosis in drug resistance hotspots in Mozambique(2020)
Authors: Fernando Chanisso Mulandane, Louwtjie P. Snyman, Denise R. A. Brito, Jeremy Bouyer, Jose Fafetine, Jan Van Den Abbeele, Marinda Oosthuizen, Vincent Delespaux, Luis Neves
- The tsetse fly displays an attenuated immune response to its secondary symbiont, Sodalis glossinidius(2019)
Authors: Katrien Trappeniers, Irina Matetovici, Jan Van Den Abbeele, Linda De Vooght
- Catalase compromises the development of the insect and mammalian stages of Trypanosoma brucei(2019)
Authors: Eva Horáková, Drahomira Faktorova, Natalia Kraeva, Binnypreet Kaur, Jan Van Den Abbeele, Vyacheslav Yurchenko, Julius Lukes
Pages: 964-977 - Innate immunity in the tsetse fly (Glossina), vector of African trypanosomes(2019)
Authors: Irina Matetovici, Linda De Vooght, Jan Van Den Abbeele
Pages: 181-188 - Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes(2019)
Authors: Geoffrey M Attardo, Adly M. M. Abd-Alla, Alvaro Acosta-Serrano, James E Allen, Rosemary Bateta, Joshua B Benoit, Kostas Bourtzis, Jelle Caers, Guy Caljon, Mikkel B Christensen, et al.