Researcher
Jan Willem Bek
- Disciplines:Histology, Musculo-skeletal systems, Developmental biology, Vertebrate biology, Genetics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Jan 2017 → 30 Sep 2018
Publications
1 - 10 of 10
- Crispant analysis in zebrafish as a tool for rapid functional screening of disease-causing genes for Osteogenesis Imperfecta(2023)Volume: 7
Authors: Sophie Debaenst, Hanna De Saffel, Jan Willem Bek, Adelbert De Clercq, Tamara Jarayseh, Lauren Sahd, Paul Coucke, Andy Willaert
Number of pages: 1 - Crispant screening in zebrafish as a promising approach for rapid functional screening of osteoporosis candidate genes and known genes for Osteogenesis Imperfecta(2022)
Authors: Sophie Debaenst, Hanna De Saffel, Jan Willem Bek, Adelbert De Clercq, Tamara Jarayseh, Lauren Sahd, Paul Coucke, Andy Willaert
Number of pages: 1 - RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition(2022)
Authors: Carolina de Carvalho Nunes, Lisa Depestel, Liselot Mus, Kaylee M. Keller, Louis Delhaye, Amber Louwagie, Muhammad Rishfi, Alex Whale, Neesha Kara, Simon R. Andrews, et al.
- A tapt1 knockout zebrafish line with aberrant lens development and impaired vision models human pediatric cataract(2022)
Authors: Tamara Jarayseh, Brecht Guillemyn, Hanna De Saffel, Jan Willem Bek, Sujatha Jagadeesh, Sofie Symoens, Fransiska Malfait, Delfien Syx, Filip Van Nieuwerburgh, Yannick Gansemans, et al.
Number of pages: 1 - Lrp5 mutant and crispant zebrafish faithfully model human osteoporosis, establishing the zebrafish as a platform for CRISPR‐based functional screening of osteoporosis candidate genes(2021)
Authors: Jan Willem Bek, Chen Shochat, Adelbert De Clercq, Hanna De Saffel, Annekatrien Boel, Juriaan Metz, Frans Rodenburg, David Karasik, Andy Willaert, Paul Coucke
Pages: 1749 - 1764 - The zebrafish in biomedical research : a vertebrate model to study skeletal disorders(2021)
Authors: Jan Willem Bek
- b3galt6 Knock-out zebrafish recapitulate β3GalT6-deficiency disorders in human and reveal a trisaccharide proteoglycan linkage region(2020)
Authors: Sarah Delbaere, Adelbert De Clercq, Shuji Mizumoto, Fredrik Noborn, Jan Willem Bek, Charlotte Gistelinck, Delfien Syx, Phil L. Salmon, Paul Coucke, Göran Larson, et al.
- The zebrafish as a model for recessive types of osteogenesis imperfecta(2019)
Authors: Jan Willem Bek, Hanna De Saffel, Osama Essawi, Adelbert De Clercq, Paul Witten, Ann Huysseune, Phil Salmon, Paul Coucke, Andy Willaert
Number of pages: 1 - Beyond the whole-mount phenotype : high-resolution imaging in fluorescence-based applications on zebrafish(2019)
Authors: Veronika Oralova, Joana Teixeira Rosa, Mieke Soenens, Jan Willem Bek, Andy Willaert, Paul Witten, Ann Huysseune
- The zebrafish as a model for fragile bone disorders(2019)
Authors: Jan Willem Bek, Hanna De Saffel, Osama Essawi, Adelbert De Clercq, Paul Witten, Ann Huysseune, Juriaan Metz, Phil Salmon, Paul Coucke, Andy Willaert
Number of pages: 1