Researcher
Johan Neyts
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Faculty of Medicine (Faculty)
Member
From1 Oct 2000 → 30 Sep 2002 - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Infrastructure
1 - 1 of 1
Projects
1 - 10 of 82
- Developing broad-spectrum antiviral drugs for pandemic preparednessFrom1 Jan 2024 → TodayFunding: HORIZON.2.1 - Health
- New AntiVirals for Infections with Pandemic PotentialFrom1 Jan 2024 → TodayFunding: HORIZON.2.1 - Health
- European Viral Outbreak Response AllianceFrom1 Jan 2024 → TodayFunding: HORIZON.1.3 - Research Infrastructures
- Classic and new strategies to fight alphavirusesFrom18 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- The Impact of SARS-CoV-2 Vaccine R&D decisions on the downstream Covid-19 Immunization System - Improving Strategic and Operational Preparedness for Future Virus Crisis OutbreakFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- Towards strategies for the treatment and prevention of henipavirus infections.From21 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- HTS to discover direct-acting small molecule inhibitors of henipavirusesFrom16 Nov 2022 → TodayFunding: Foreign private sponsor - undefined
- Prepared for SARS-CoV-3: advancing our understanding of SARS coronavirus antigenic and pathogenic evolutionFrom1 Jan 2022 → TodayFunding: FWO EOS
- VirusBank platform (state-of-the-art research platform for increased preparedness against viral epidemics and pandemics)From1 Jan 2022 → TodayFunding: Ministery of Economical Affairs
Publications
41 - 50 of 621
- Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells(2023)
Authors: Roeland Vanhoutte, Dirk Jochmans, Steven De Jonghe, Johan Neyts, Steven Verhelst
Pages: 1666 - 1672 - A pan-serotype antiviral to prevent and treat dengue: A journey from discovery to clinical development driven by public-private partnerships(2023)
Authors: Johan Neyts
- Development of a robust and convenient dual-reporter high-throughput screening assay for SARS-CoV-2 antiviral drug discovery(2023)
Authors: Kayvan Abbasi, Dirk Jochmans, Steven De Jonghe, Hendrik Jan Thibaut, Johan Neyts, Manon Laporte, Pieter Leyssen
- Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates(2023)
Authors: Rana Abdelnabi, Dominique Schols, Johan Neyts
- Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives(2023)
Authors: Johan Neyts, Dirk Jochmans, Steven De Jonghe
- Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71(2023)
Authors: Dirk Jochmans, Johan Neyts
- Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase(2023)
Authors: Jana Van Dycke, Johan Neyts, Joana Duarte Da Rocha Pereira
- Identification of Polyphenol Derivatives as Novel SARS-CoV-2 and DENV Non-Nucleoside RdRp Inhibitors(2023)
Authors: Hongtao Xu, Merel Oeyen, Steven De Jonghe, Dirk Jochmans, Johan Neyts, Piet Herdewyn, Dominique Schols
- The Role of Histo-Blood Group Antigens and Microbiota in Human Norovirus Replication in Zebrafish Larvae(2022)
Authors: Arno Cuvry, Dufie Strubbe, Johan Neyts, Peter de Witte, Joana Duarte Da Rocha Pereira
- Combination of the parent analogue of remdesivir (GS-441524) and molnupiravir results in a markedly potent antiviral effect in SARS-CoV-2 infected Syrian hamsters(2022)
Authors: Rana Abdelnabi, Piet Maes, Steven De Jonghe, Birgit Weynand, Johan Neyts
Patents
1 - 10 of 10
- Corona virus binders (Inventor)
- Lassavirus vaccines (Inventor)
- Chimeric filovirus vaccines (Inventor)
- Chimeric zika-japanese encephalitis virus (Inventor)
- Chimeric yellow fever zika virus strain (Inventor)
- Viral replication inhibitors (Inventor)
- Treatment and prevention of dengue disease (Inventor)
- Coronavirus vaccines (Inventor)
- Design synthesis and methods of use of acyclic fleximer nucleoside analogues having anti-coronavirus activity (Inventor)
- Treatment and prevention of dengue disease (Inventor)