< Back to previous page
Researcher
Johan Swinnen
- Disciplines:Oncology, Medical systems biology
Affiliations
- Laboratory of Lipid Metabolism and Cancer (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Lipid Metabolism and Cancer (Division)
Member
From1 Jan 2012 → Today - Clinical and Experimental Endocrinology (Division)
Member
From1 Jan 2003 → 31 Dec 2011 - Department of Development and Regeneration (Department)
Member
From1 Oct 2000 → 31 Dec 2002
Infrastructure
1 - 2 of 2
- An high-throughput automated small molecule screening platform (Consortium coordinator)
- Next Generation Magnetic Resonance Mass Spectrometry. (Consortium coordinator)
Projects
1 - 10 of 51
- Targeting lipid metabolism to overcome cancer therapy resistanceFrom1 Apr 2024 → TodayFunding: IOF - mandates
- Een uitgebreide pijplijn voor translationeel onderzoek en training die het lipidenmetabolisme benut om de behandeling van prostaatkanker te verbeteren en jonge onderzoekers op te leiden in de aanpak van complexe ziektenFrom1 Jan 2024 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- A Comprehensive Translational Research and Training Pipeline Harnessing Lipid Metabolism to Improve Prostate Cancer Management and Educate Young Researchers in Tackling Complex DiseaseFrom1 Jan 2024 → TodayFunding: BOF - projects
- Chemical Imaging of Biological Systems by Mass Spectrometry Imaging-enhanced Coherent Raman Scattering MicroscopyFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- 4D-Lipidomics: a new standard in advanced lipidomics researchFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- LipoMacs: functional Lipidomics to unlock Macrophage-mediated therapyFrom1 Oct 2022 → TodayFunding: FWO Strategic Basic Research (SBO)
- Multimodal Coherent Raman Scattering /Fluorescence Lifetime Imaging Microscopy systemFrom2 Aug 2022 → TodayFunding: Other federal scientific institutions
- An high-throughput automated small molecule screening platform.From1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Aggressive salivary gland neoplasms: institutional-international collaborative evaluation of advances in clinical management and translational research into tumor biologyFrom11 Jan 2022 → 31 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
Publications
1 - 10 of 133
- Peroxisomal β-oxidation enzyme, DECR2, regulates lipid metabolism and promotes treatment resistance in advanced prostate cancer(2024)
Authors: Jonas Dehairs, Johan Swinnen
- Fatty acid elongation regulates mitochondrial 13-oxidation and cell viability in prostate cancer by controlling malonyl-CoA levels(2024)
Authors: Johan Swinnen
- Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.(2024)
Authors: Yingli Zhu, Yoke Chin Chai, Patrizia Agostinis, Johan Swinnen
Pages: 6 - Extracellular vesicle-associated cholesterol supports the regenerative functions of macrophages in the brain(2023)
Authors: Jonas Dehairs, Johan Swinnen
- Fatty acid elongation by ELOVL6 hampers remyelination by promoting inflammatory foam cell formation during demyelination(2023)
Authors: Jonas Dehairs, Johan Swinnen
- Targeting lipid metabolism to overcome therapy resistance in pancreatic cancer(2023)
Authors: Vincent de Laat, Johan Swinnen
- C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress-Induced Ferroptosis in FLT3-Mutant Leukemia(2023)
Authors: Jonas Dehairs, Johan Swinnen
Pages: 1720 - 1747 - A fat lot of good: A novel monounsaturated fatty acid promotes prostate cancer growth and survival(2023)
Authors: Jonas Dehairs, Johan Swinnen
- Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity(2023)
Authors: Jonas Dehairs, Johan Swinnen
Pages: 666 - 679 - Phospholipase D3 degrades mitochondrial DNA to regulate nucleotide signaling and APP metabolism(2023)
Authors: Zoë Van Acker, Anna Perdok, Katherine North, Jonas Dehairs, Johan Swinnen, Wim Annaert
Patents
1 - 5 of 5
- Screening methods for compounds modulating polyamine transport (Inventor)
- Combination treatment of arsenic oxide and antiandrogens (Inventor)
- Cancer phospholipidome (Inventor)
- CANCER PHOSPHOLIPIDOME (Inventor)
- PHOSPHOLIPID PROFILING OF CANCER (Inventor)