Researcher
John Creemers
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Biochemical Neuroendocrinology (Division)
Responsible
From1 Jan 2006 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 26
- Replace a broken freeze substitution low temperature embedding system for light and electron microscopy (Leica EM AFS2)From1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Unraveling the pathology of the novel congenital myasthenic syndrome-22 (CMS22) and investigation of molecular links with Prader-Willi syndrome.From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- the role of Furin in colorectal cancerFrom1 Apr 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PREPL, a serine hydrolase deleted in patients with a Prader Willi-like syndrome; functional characterization and exploration of novel therapeutic avenues.From19 Aug 2019 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- PREPL, a serine hydrolase deleted in patients with a Prader Willi-like syndrome; functional characterization and exploration of novel therapeutic avenuesFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Therapeutic targeting of PC1/3 deficiency: from obesity to gastrointestinal disordersFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Functional characterization of PREPL, a serine hydrolase deleted in patients with a Prader Willi-like syndrome, and evaluation of new medication for the treatment of myastheniaFrom1 Oct 2016 → 30 Sep 2020Funding: BOF - Concerted Research Project from 1994
- Repair and upgrade of the high resolution biological SEMFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- The role of the proprotein convertases in diabetes and obesityFrom1 Sep 2016 → 12 Jul 2022Funding: FWO fellowships
- Functional characterization of PREPL and the role in Prader-Willi syndromeFrom1 Jan 2015 → 13 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
31 - 40 of 91
- PCSK1 mutations and human endocrinopathies: from obesity to gastrointestinal disorders(2016)
Authors: Pieter Stijnen, Bruno Ramos Molina, John Creemers
Pages: 347 - 371 - Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity(2016)
Authors: Pieter Stijnen, Bas Brouwers, Eva Dirkx, Frans Schuit, Lieven Thorrez, Jeroen Declercq, John Creemers
Pages: 973 - 981 - Characterizing the function of Neurobeachin, a candidate gene for autism spectrum disorders(2016)
Authors: Krizia Tuand, John Creemers, Claudia Bagni
Number of pages: 218 - Nuclear Localization of the Autism Candidate Gene Neurobeachin and Functional Interaction with the NOTCH1 Intracellular Domain Indicate a Role in Regulating Transcription(2016)
Authors: Krizia Tuand, Pieter Stijnen, Jeroen Declercq, John Creemers
- Human Growth Hormone in Transgenesis: A Growing Problem?(2015)
Authors: Bas Brouwers, John Creemers
Pages: 3648 - 50 - Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone(2015)
Authors: Jeroen Declercq, Bas Brouwers, Pieter Stijnen, Krizia Tuand, Anica Schraenen, Frans Schuit, John Creemers
- THE AUTHORS REPLY : The Association of Common Variants in PCSK1 with Obesity: A huge Review and Meta-Analysis(2015)
Authors: Pieter Stijnen, Krizia Tuand, Bert Aertgeerts, John Creemers
Pages: 733 - 735 - THE AUTHORS REPLY : The Association of Common Variants in PCSK1 with Obesity: A huge Review and Meta-Analysis(2015)
Authors: Pieter Stijnen, Krizia Tuand, Tibor V Varga, Paul W Franks, Bert Aertgeerts, John Creemers
Pages: 733 - 735 - A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity(2015)
Authors: Pieter Stijnen, John Creemers
Pages: 295 - 302 - Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer(2015)
Authors: Jeroen Declercq, Bart Jacobs, Bart Biesmans, Arnaud Roth, Dirk Klingbiel, Sabine Tejpar, John Creemers
Pages: 321276