Researcher
John Creemers
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Laboratory for Biochemical Neuroendocrinology (Division)
Responsible
From1 Jan 2006 → Today - Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 26
- Replace a broken freeze substitution low temperature embedding system for light and electron microscopy (Leica EM AFS2)From1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Unraveling the pathology of the novel congenital myasthenic syndrome-22 (CMS22) and investigation of molecular links with Prader-Willi syndrome.From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- the role of Furin in colorectal cancerFrom1 Apr 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring metabolic pathways that link Congenital Myasthenic Syndrome-22, caused by PREPL deficiency to Prader-Willi SyndromeFrom19 Aug 2019 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- PREPL, a serine hydrolase deleted in patients with a Prader Willi-like syndrome; functional characterization and exploration of novel therapeutic avenuesFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Therapeutic targeting of PC1/3 deficiency: from obesity to gastrointestinal disordersFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Functional characterization of PREPL, a serine hydrolase deleted in patients with a Prader Willi-like syndrome, and evaluation of new medication for the treatment of myastheniaFrom1 Oct 2016 → 30 Sep 2020Funding: BOF - Concerted Research Project from 1994
- Repair and upgrade of the high resolution biological SEMFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- The role of the proprotein convertases in diabetes and obesityFrom1 Sep 2016 → 12 Jul 2022Funding: FWO fellowships
- Functional characterization of PREPL and the role in Prader-Willi syndromeFrom1 Jan 2015 → 13 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
41 - 50 of 91
- The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B: AN OPPORTUNITY TO REDUCE THE SPECIFIC INSULIN RECEPTOR-DEPENDENT EFFECTS OF INSULIN-LIKE GROWTH FACTOR 2 (IGF2)(2015)
Authors: John Creemers
Pages: 2812 - 21 - Single Nucleotide Polymorphism (rs4932178) in the P1 Promoter of FURIN Is Not Prognostic to Colon Cancer(2015)
Authors: Jeroen Declercq, Sabine Tejpar, John Creemers
Pages: 321276 - 321276 - The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B: AN OPPORTUNITY TO REDUCE THE SPECIFIC INSULIN RECEPTOR-DEPENDENT EFFECTS OF INSULIN-LIKE GROWTH FACTOR 2 (IGF2)(2015)
Authors: Imène Kara, Marjorie Poggi, Bernadette Bonardo, Roland Govers, Jean-François Landrier, Sun Tian, Ingo Leibiger, Robert Day, John Creemers, Franck Peiretti
Pages: 2812 - 21 - Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth(2015)
Authors: Jeroen Declercq, Bas Brouwers, Vincent Pruniau, Pieter Stijnen, Krizia Tuand, John Creemers
Pages: 148651 - 148651 - Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression(2014)
Authors: Bas Brouwers, Geoffroy de Faudeur, Lotte Goyvaerts, Katleen Lemaire, Leen Boesmans, Vincent Pruniau, Jeroen Declercq, John Creemers, Frans Schuit, Anica Schraenen
Pages: 979 - 990 - Impaired Islet Function in Commonly Used Transgenic Mouse Lines due to Human Growth Hormone Minigene Expression(2014)
Authors: Bas Brouwers, Geoffroy de Faudeur, Anna B Osipovich, Lotte Goyvaerts, Katleen Lemaire, Leen Boesmans, Elisa JG Cauwelier, Mikaela Granvik, Vincent Pruniau, Leentje Van Lommel, et al.
Pages: 979 - 990 - The Association of Common Variants in PCSK1 With Obesity: A HuGE Review and Meta-Analysis(2014)
Authors: Pieter Stijnen, Krizia Tuand, Bert Aertgeerts, John Creemers
Pages: 1051 - 1065 - The Dwarf Phenotype in GH240B Mice, Haploinsufficient for the Autism Candidate Gene Neurobeachin, Is Caused by Ectopic Expression of Recombinant Human Growth Hormone(2014)
Authors: Krizia Tuand, Pieter Stijnen, Hugo Vankelecom, John Creemers
- PREPL deficiency with or without cystinuria causes a novel myasthenic syndrome(2014)
Authors: Luc Régal, Chantal Verhille, John Creemers
Pages: 1254 - 1260 - Deletion of prepl causes growth impairment and hypotonia in mice(2014)
Authors: John Creemers