Researcher
Joost Schymkowitz
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Proteins, Bioinformatics of disease, Structural bioinformatics and computational proteomics, Synthetic biology, Proteomics
- See also: Joost Schymkowitz (Flanders Institute for Biotechnology)
Affiliations
- Switch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Infrastructure
1 - 1 of 1
- When size matters: a platform to study molecular interactions and multimerisation (Consortium coordinator)
Projects
1 - 10 of 54
- The Hidden Biology of Inclusion BodiesFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- New molecular tools for diagnostic and treatment of systemic amyloidosisFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Structural and morphological studies of heterotypic amyloid fibrilsFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Cotranslational protein folding and aggregationFrom4 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of Heterotypic Interactions of TDP-43 Aggregation in NeurodegenerationFrom11 Apr 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Characterization of novel antibiotics against bacterial protein secretion.From1 Apr 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Rational design of biologics for therapeutic development (FoldCo)From19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
31 - 40 of 159
- Bioavailability and Health Impact of Ingested Amyloid-like Protein Fibrils and their Link with Inflammatory Status: A Need for More Research?(2022)
Authors: Jan Delcour, Frederic Rousseau, Joost Schymkowitz
- Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis(2022)
Authors: Nicolas Rosa, Rita La Rovere, Nikolaos Louros, Lily Karamanou, Frederic Rousseau, Joost Schymkowitz, Tassos Economou, Jan Parys, Geert Bultynck
Pages: 788 - 805 - StAmP-DB: a platform for structures of polymorphic amyloid fibril cores(2022)
Authors: Nikolaos Louros, Rob van der Kant, Joost Schymkowitz, Frederic Rousseau
Pages: 2636 - 2638 - Heterotypic interactions in amyloid function and disease(2022)
Authors: Katerina Konstantoulea, Nikolaos Louros, Frederic Rousseau, Joost Schymkowitz
Pages: 2025 - 2046 - Mapping the sequence specificity of heterotypic amyloid interactions enables the identification of aggregation modifiers(2022)
Authors: Nikolaos Louros, Emiel Michiels, Katerina Konstantoulea, Dietmar Thal, Frederic Rousseau, Joost Schymkowitz
- Protein structure and aggregation: a marriage of necessity ruled by aggregation gatekeepers(2022)
Authors: Bert Houben, Frederic Rousseau, Joost Schymkowitz
Pages: 194 - 205 - PyUUL provides an interface between biological structures and deep learning algorithms(2022)
Authors: Gabriele Orlando, Daniele Raimondi, Yves Moreau, Joost Schymkowitz, Frederic Rousseau
- Heterotypic amyloid interactions: Clues to polymorphic bias and selective cellular vulnerability?(2022)
Authors: Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau
Pages: 176 - 186 - Heterotypic Amyloid β interactions facilitate amyloid assembly and modify amyloid structure(2022)
Authors: Katerina Konstantoulea, Nikolaos Louros, Bert Houben, Emiel Michiels, Matthias De Vleeschouwer, Joost Schymkowitz, Frederic Rousseau
- HPMPdb: A machine learning-ready database of protein molecular phenotypes associated to human missense variants(2022)
Authors: Daniele Raimondi, Joost Schymkowitz, Frederic Rousseau, Yves Moreau
Pages: 167 - 174
Patents
1 - 10 of 10
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Beta-lactamase inhibitors (Inventor)
- Carbon dioxide generation (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Means and methods for the prediction of amyloid core sequences (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)
- Carbon dioxide generation (Inventor)