Researcher
Joost Schymkowitz
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Behavioural neuroscience
- Disciplines (KU Leuven):Proteins, Bioinformatics of disease, Structural bioinformatics and computational proteomics, Synthetic biology, Proteomics
- See also: Joost Schymkowitz (Flanders Institute for Biotechnology)
Affiliations
- Switch Lab (Research group)
Responsible
From1 Jan 2017 → Today - Switch Laboratory (VIB-KU Leuven) (Division)
Member
From1 Jan 2011 → Today - Department of Cellular and Molecular Medicine (Department)
Member
From15 Sep 2010 → 31 Dec 2010
Infrastructure
1 - 1 of 1
- When size matters: a platform to study molecular interactions and multimerisation (Consortium coordinator)
Projects
1 - 10 of 54
- The Hidden Biology of Inclusion BodiesFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- New molecular tools for diagnostic and treatment of systemic amyloidosisFrom2 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Structural and morphological studies of heterotypic amyloid fibrilsFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Heterotypic aggregation of Aβ42 with disease-relevant proteins in Alzheimer’s diseaseFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Cotranslational protein folding and aggregationFrom4 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Investigation of Heterotypic Interactions of TDP-43 Aggregation in NeurodegenerationFrom11 Apr 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Characterization of novel antibiotics against bacterial protein secretion.From1 Apr 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Convergence of tau and TDP-43 in Alzheimer's: towards a multitarget diagnosisFrom1 Dec 2021 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Rational design of biologics for therapeutic development (FoldCo)From19 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
41 - 50 of 159
- The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation(2021)
Authors: Bert Houben, Rodrigo Gallardo, Matthias De Vleeschouwer, Samantha Louise Edwards, Frederic Rousseau, Joost Schymkowitz
- SINGLE-CELL DRUG ACTIVITY MAPPING IN GLIOBLASTOMA IDENTIFIES EXTENDED DRUG RESPONSE HETEROGENEITY AND THERAPY-INDUCED CELLULAR PLASTICITY(2021)
Authors: Dena Panovska, Raf Sciot, Paul Clement, Frederic Rousseau, Joost Schymkowitz, Steven De Vleeschouwer, Frederik De Smet
Pages: 167 - 167 - Erratum for Mortier and Gayán et al., "Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness".(2021)
Authors: Julien Mortier, Elisa Gayán, Ronald Van Eyken, Oscar Enrique Torres Montaguth, Laleh Khodaparast, Ladan Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, et al.
Pages: e0246721 - Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions(2021)
Authors: Katerina Konstantoulea, Frederic Rousseau, Joost Schymkowitz
- In silico prediction of in vitro protein liquid-liquid phase separation experiments outcomes with multi-head neural attention(2021)
Authors: Daniele Raimondi, Gabriele Orlando, Emiel Michiels, Ludo Van Den Bosch, Yves Moreau, Frederic Rousseau, Joost Schymkowitz
Pages: 3473 - 3479 - Investigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins(2021)
Authors: Guiqin Wu, Joost Schymkowitz, Frederic Rousseau, Laleh Khodaparast, Ladan Khodaparast
- Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets(2021)
Authors: Kaat Luyten, Laleh Khodaparast, Ladan Khodaparast, Filip Claes, Rodrigo Gallardo, Michel Koole, Joost Schymkowitz, Guy Bormans, Frederic Rousseau
Pages: 2052 - 2064 - The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation(2021)
Authors: Liselot Dewachter, Celien Bollen, Dorien Wilmaerts, Elen Louwagie, Paul Matthay, Laleh Khodaparast, Ladan Khodaparast, Frederic Rousseau, Joost Schymkowitz, Jan Michiels
- Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness(2021)
Authors: Julien Mortier, Ronald Van Eyken, Laleh Khodaparast, Ladan Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, Abram Aertsen
- Bacterial Protein Homeostasis Disruption as a Therapeutic Intervention(2021)
Authors: Laleh Khodaparast, Guiqin Wu, Ladan Khodaparast, Bela Z Schmidt, Frederic Rousseau, Joost Schymkowitz
Patents
1 - 10 of 10
- Molecules targeting ras protein (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Beta-lactamase inhibitors (Inventor)
- Carbon dioxide generation (Inventor)
- Molecules targeting mutant ras protein (Inventor)
- Means and methods for the prediction of amyloid core sequences (Inventor)
- Molecules targeting proteins (Inventor)
- Molecules targeting ras protein (Inventor)
- Carbon dioxide generation (Inventor)