Researcher
Joris Vriens
- Disciplines:Electrophysiology, Fertility
Affiliations
- Woman and Child (Division)
Responsible
From1 Jan 2019 → Today - Woman and Child (Division)
Member
From1 Apr 2013 → Today - Laboratory of Ion Channel Research (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → 30 Sep 2011
Projects
1 - 10 of 28
- Characterization of a disease model for a TRPM3 channelopathy causing developmental and epileptic encephalopathiesFrom9 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Early folliculogenesis and ovarian aging in women with genetic predisposition to (breast)cancerFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- TRPM3 variants underlie neurodevelopmental disorders and epileptic encephalopathiesFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- "PAR-2, a maternal sensor to detect embryonic signals"From1 Nov 2021 → TodayFunding: FWO fellowships
- Investigating the role of calcium in the branching process of the chorioallantoic placentaFrom1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- Validation of TRPM3 as a target for neuropathic painFrom1 Oct 2021 → 31 Dec 2023Funding: IOF - technology validation in lab
- Automated slide scanner for digitalizing histopathologyFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- Development of novel in vitro and in vivo models to investigate the infertility problems of patients with polycystic ovary syndromeFrom12 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- A kinetic, high-throughput cellular screening system (Plate Imaging Reader) for the "real time" monitoring of dynamic intracellular Ca2+ signals in living cellsFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- In vitro and in vivo characterization of a gain-of-function mutation of TRPM3 associated with peripheral disability and epilepsyFrom1 Oct 2019 → TodayFunding: FWO fellowships
Publications
1 - 10 of 121
- Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling(2024)
Authors: Jonathan Chui, Aneta Malesa, Paraskevi ATHANASOULI, Joris Vriens, Kian Koh, Catherine Verfaillie, Frederic Lluis Vinas
- The Concise Guide to PHARMACOLOGY 2023/24: Ion channels(2023)
Authors: Joris Vriens
Pages: S145 - S222 - TRPM3 as a novel target to alleviate acute oxaliplatin-induced peripheral neuropathic pain(2023)
Authors: Davide Aloi, Thomas Voets, Joris Vriens
Pages: 2060 - 2069 - Prenatally androgenized PCOS-like mice present with dysregulated endometrium during window of implantation (WOI) and decidualization(2023)
Authors: Joris Vriens
- Primidone improves symptoms in TRPM3-linked developmental and epileptic encephalopathy with spike-and-wave activation in sleep(2023)
Authors: Evelien Van Hoeymissen, Thomas Voets, Joris Vriens
Pages: e61 - e68 - Protease secretions by the invading blastocyst induce calcium oscillations in endometrial epithelial cells via the protease-activated receptor 2(2023)
Authors: Katrien De Clercq, Karen Peeraer, Hugo Vankelecom, Thomas Voets, Joris Vriens
- The impact of chronic endometritis on infertility: prevalence, reproductive outcomes, and the role of hysteroscopy as a screening tool(2023)
Authors: Brecht Geysenbergh, Celine Bafort, Anne-Sophie Van Rompuy, Sharon Lie Fong, Sophie Debrock, Joris Vriens, Eline Dancet, Thomas D'Hooghe, Karen Peeraer
Pages: 108 - 115 - Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure-Activity Relationship(2023)
Authors: Thomas Voets, Joris Vriens, Steven Verhelst
Pages: 456 - 464 - Gain- of- function variants in the ion channel gene TRPM3 underlie a spectrum of neurodevelopmental disorders(2023)
Authors: Evelien Van Hoeymissen, Katrien De Clercq, Thomas Voets, Joris Vriens
- Assessment of the Functional Expression of TRPM3 and TRPV1 in Endometriosis Using Ex Vivo Calcium Imaging(2023)
Authors: Eleonora Persoons, Carla Tomassetti, Joris Vriens
Pages: 67A - 67A
Patents
1 - 4 of 4
- Aryl derivatives for treating trpm3 mediated disorders (Inventor)
- Heterocycle derivatives for treating trpm3 mediated disorders (Inventor)
- Screening method for analgesic agents (Inventor)
- Treatment of pain (Inventor)