Researcher
Julie De Backer
- Keywords:Aortic dissection, Marfan syndrome, Aortic Aneurysm, Cardiogenetics, congenital heart disease
- Disciplines:Vascular diseases, Cardiology, Cardiac and vascular medicine not elsewhere classified, Genetics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 30 Sep 2023 - Department of Internal medicine (Department)
Member
From1 Oct 2011 → 30 Sep 2018 - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2001 → 30 Sep 2018
Projects
1 - 8 of 8
- Unraveling the mechanisms that drive cardiovascular manifestations in Marfan syndrome using mouse modelsFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- Paving the way to precision medicine in childhood-onset diseases: A lifespan perspective on accelerated aging using the epigenetic clockFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- A zebrafish platform for genetic and chemical screening to improve diagnosis, risk estimation and treatment of cardiovascular manifestations in Marfan syndrome.From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Human stem cell-derived models to unveil mechanisms of impaired myocardial function in Marfan SyndromeFrom1 Oct 2019 → TodayFunding: BOF - projects
- Using advanced fluid dynamics modelling for cardiovascular phenotyping of zebrafish modelsFrom1 Oct 2018 → TodayFunding: BOF - Doctoral projects
- Using Zebrafish as a novel tool to Improve the Diagnosis and Outcome of Marfan SyndromeFrom1 Sep 2018 → 31 Aug 2020Funding: H2020-EU.1.3.- EXCELLEN SCIENCE - Marie Skłodowska-Curie actions
- From gene to aortic dissection - detailed study of the etiology and pathogenesis and of cardiovascular characteristics of inheritable thoracic aortic aneurysms and dissectionsFrom1 Mar 2013 → 31 Oct 2018Funding: BOF - Doctoral projects
Publications
31 - 40 of 83
- MEK1/2 inhibition in murine heart and aorta after oral administration of refametinib supplemented drinking water(2020)
Authors: Felke Steijns, Nathalie Bracke, Marjolijn Renard, Julie De Backer, Patrick Sips, Nathan Debunne, Evelien Wynendaele, Frederick Verbeke, Bart De Spiegeleer, Laurence Campens
- Effects of fibrillin mutations on the behavior of heart muscle cells in Marfan syndrome(2020)
Authors: Jeffrey Aalders, Laurens Léger, Louis Van der Meeren, Natasja Van den Vreken, Andre Skirtach, Sanjay Sinha, Julie De Backer, Jolanda van Hengel
- Corrosion casting of the cardiovascular structure in adult zebrafish for analysis by scanning electron microscopy and X‐ray microtomography(2020)
Authors: Ward De Spiegelaere, Lisa Caboor, Matthias Van Impe, Matthieu Boone, Julie De Backer, Patrick Segers, Patrick Sips
Pages: 635 - 642 - Spontaneous right ventricular pseudoaneurysms and increased arrhythmogenicity in a mouse model of Marfan syndrome(2020)
Authors: Felke Steijns, Marjolijn Renard, Marine Vanhomwegen, Petra Vermassen, Jana Desloovere, Robrecht Raedt, Lars Emil Larsen, Máté István Tóth, Julie De Backer, Patrick Sips
- The ESC clinical practice guidelines for the management of adult congenital heart disease 2020(2020)
Authors: H Baumgartner, Julie De Backer
Pages: 4153 - 4154 - Vascular Ehlers-Danlos syndrome management : the Paris way, a step forward on a long road(2019)
Authors: Julie De Backer, Tine De Backer
Pages: 1958 - 1960 - European reference network for rare vascular diseases (VASCERN) consensus statement for the screening and management of patients with pathogenic ACTA2 variants(2019)
Authors: Infrid MBH van de Laar, Eloisa Arbustini, Bart Loeys, Erik Björck, Lise Murphy, Maarten Groenink, Marlies Kempers, Janneke Timmermans, Jolien Roos-Hesselink, Kalman Benke, et al.
- Cardiovascular disease and pregnancy : when the heart matters(2019)
Authors: Julie De Backer, Els Troost
Pages: 17 - 23 - Case-matched comparison of cardiovascular outcome in Loeys-Dietz syndrome versus Marfan syndrome(2019)
Authors: Kristina Mühlstädt, Julie De Backer, Yskert von Kodolitsch, Kerstin Kutsche, Laura Muiño Mosquera, Jens Brickwedel, Evaldas Girdauskas, Thomas S Mir, Adrian Mahlmann, Nikolaos Tsilimparis, et al.
- Angiotensin-II receptor blockade in Marfan syndrome(2019)
Authors: Laura Muiño Mosquera, Julie De Backer
Pages: 2206 - 2207