Researcher
Katrien Remaut
- Keywords:lipid nanoparticles, mRNA delivery, innate immunity, peritoneal carcinomatosis, non-viral gene delivery, ocular gene therapy
- Disciplines:Nanobiotechnology, Other biological sciences not elsewhere classified, Environmental safety and health of nanotechnology, Nanoscale characterisation, Nanotechnology not elsewhere classified, Nanophotonics, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, Other pharmaceutical sciences not elsewhere classified, Biopharmaceuticals, In vitro testing, Non-clinical studies, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2001 → Today
Infrastructure
1 - 1 of 1
- Confocal and two-photon Microscope (Consortium partner)
Projects
1 - 10 of 29
- ILM photodisruption: a biophotonic approach to promote retinal ganglion cell engraftment as a cure for blindnessFrom1 Nov 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Postdoctoral Fellowship Program in National Glaucoma Research: "“Exploring ICG-mediated ILM photodisruption as a tool to boost retinal ganglion cell engraftment"From1 Jul 2023 → TodayFunding: Foreign private sponsor - undefined
- Let There Be Light: two biophotonic approaches to boost retinal ganglion cell transplantation as a cure for blindnessFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Nanoparticle formulations of toll-like receptor agonists and oxaliplatin for local intraperitoneal delivery to treat colorectal peritoneal metastasisFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- INTRAPERITONEAL IMMUNE MODULATION FOR COLORECTAL PERITONEAL METASTASESFrom1 Nov 2022 → TodayFunding: FWO research project (including WEAVE projects)
- In vivo evaluation of the expression kinetics and immunogenicity of lipid nanoparticle mediated messenger RNA and self-amplifying messenger RNA delivery to the retinaFrom18 Apr 2022 → 17 Apr 2023Funding: Foundations, funds and other with scientific goal
- Toekenning: ARVO Foundation for Eye Research and the Eye Bank Association of America EyeFind Research: "Grant Karen Peynshaert"From1 Feb 2022 → 31 Jan 2023Funding: Foreign Nonprofit organisations and equivalents
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Intraperitoneal Aerosolized Liposomal Irinotecan (NalIRI) in Peritoneal Carcinomatosis from GI cancer: a phase I firstinhuman studyFrom1 Aug 2021 → TodayFunding: Private funding of national origin - undefined
- Genetic therapy for EYS- and USH2A-associated retinal dystrophy ("GET-READY")From1 Jun 2021 → TodayFunding: FWO research project (including WEAVE projects)
Publications
11 - 20 of 90
- A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs(2022)
Authors: Bram Bogaert, Felix Sauvage, Roberta Guagliardo, Cristina Muntean, [missing] Van Phuc Nguyen, Eline Pottie, Mike Wels, An-Katrien Minnaert, Qiangbing Yang, Dan Peer, et al.
Pages: 256 - 270 - ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery(2022)
Authors: Karen Peynshaert, Helena Vanluchene, Kaat De Clerck, An-Katrien Minnaert, Morgane Verhoeven, Noémie Gouspillou, Nezahat Bostan, Toshio Hisatomi, Geraldine Accou, Félix Sauvage, et al.
Pages: 315 - 326 - Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across(2021)
Authors: An-Katrien Minnaert, Helena Vanluchene, Rein Verbeke, Ine Lentacker, Koen Raemdonck, Niek Sanders, Katrien Remaut
- Aerosolization of thermosensitive hydrogels using pressurized intraperitoneal aerosol chemotherapy (PIPAC)(2021)Volume: 28
Authors: Mohammad Rahimi Gorji, Helena Braet, Charlotte Debbaut, Ghader Ghorbaniasl, Katrien Remaut, Wim Ceelen
Pages: S110 - S110 - Together is better : mRNA co‐encapsulation in lipoplexes is required to obtain ratiometric co‐delivery and protein expression on the single cell level(2021)
Authors: Heyang Zhang, Jeroen Bussmann, Florian H. Huhnke, Joke Devoldere, An-Katrien Minnaert, Wim Jiskoot, Friedhelm Serwane, Joachim Spatz, Magnus Röding, Stefaan De Smedt, et al.
- Exploring high pressure nebulization of pluronic F127 hydrogels for intraperitoneal drug delivery(2021)
Authors: Helena Braet, Mohammad Rahimi Gorji, Charlotte Debbaut, G Ghorbaniasl, Thibault Van Walleghem, Senne Cornelis, Chris Vervaet, Wim Ceelen, Katrien Remaut
Pages: 134 - 143 - Lipoplexes to deliver oligonucleotides in gram-positive and gram-negative bacteria : towards treatment of blood infections(2021)
Authors: Sara Pereira, Rita Sobral Santos, Luís Moreira, Nuno Guimarães, Mariana Gomes, Heyang Zhang, Katrien Remaut, Kevin Braeckmans, Nuno Filipe Azevedo
- Vaccinia virus protein B18R : influence on mRNA immunogenicity and translation upon non-viral delivery in different ocular cell types(2021)
Authors: An-Katrien Minnaert, Joke Devoldere, Karen Peynshaert, Laure Vercruysse, Katrien Remaut
- Synergy between intraperitoneal aerosolization (PIPAC) and cancer nanomedicine : cisplatin-loaded polyarginine-hyaluronic acid nanocarriers efficiently eradicate peritoneal metastasis of advanced human ovarian cancer(2020)
Authors: Molood Shariati, Giovanna Lollo, Kevin Matha, Benedicte Descamps, Christian Vanhove, Leen Van de Sande, Lieve Balcaen, Jean-Pierre Benoit, Wim Ceelen, Katrien Remaut
Pages: 29024 - 29036 - Intraperitoneal aerosolized drug delivery : technology, recent developments, and future outlook(2020)
Authors: Mohammad Rahimi Gorji, Leen Van de Sande, Charlotte Debbaut, Ghader Ghorbaniasl, Helena Braet, Katrien Remaut, Wim Ceelen
Pages: 105 - 114
Patents
1 - 2 of 2