Researcher
Katrien Remaut
- Keywords:lipid nanoparticles, mRNA delivery, innate immunity, peritoneal carcinomatosis, non-viral gene delivery, ocular gene therapy
- Disciplines:Nanobiotechnology, Other biological sciences not elsewhere classified, Environmental safety and health of nanotechnology, Nanoscale characterisation, Nanotechnology not elsewhere classified, Nanophotonics, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, Other pharmaceutical sciences not elsewhere classified, Biopharmaceuticals, In vitro testing, Non-clinical studies, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2001 → Today
Infrastructure
1 - 1 of 1
- Confocal and two-photon Microscope (Consortium partner)
Projects
11 - 20 of 29
- Targeting the Tumor Microenvironment in Colorectal Peritoneal MetastasesFrom1 Jan 2021 → TodayFunding: BOF - projects
- Design of a novel antisense oligonucleotide therapy for inherited blindnessFrom1 Nov 2020 → 31 Oct 2021Funding: BOF - doctoral mandates
- Precision medicine in inherited blindness using integrated omics in human and animal modelsFrom1 Jan 2020 → TodayFunding: BOF - projects
- ICG-mediated photoporation of the inner limiting membrane to enhance retinal drug delivery after intravitreal injection.From1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Barriers and carriers for non-viral delivery of mRNA to induce transient protein expression in the retina: the hurdles of the inner limiting membrane and innate immunity versus the potential of mRNA self-amplification.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships
- Barriers and carriers for non-viral delivery of mRNA to induce transient protein expression in the retina: the hurdles of the inner limiting membrane and innate immunity versus the potential of mRNA self-amplification.From1 Oct 2019 → 1 Nov 2019Funding: BOF - doctoral mandates
- High pressure intraperitoneal aerosolization of chemotherapeutics, nanoparticles and hydrogels to treat peritoneal carcinomatosis: effect on tumor penetration, biodistribution and anti-cancer activity.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Intraperitoneal nebulization of thermosensitive hydrogels for the controlled release of chemotherapeutics and biopharmaceuticals to treat peritoneal carcinomatosisFrom1 Jan 2019 → 31 Mar 2023Funding: FWO Strategic Basic Research Grant
- Photoporation of the inner limiting membrane to enhance retinal drug delivery after intravitreal injectionFrom1 Oct 2018 → 30 Sep 2022Funding: FWO fellowships
- Laser bench for laser scanning confocal microscopyFrom1 Jun 2018 → 31 May 2020Funding: BOF - Other initiatives
Publications
1 - 10 of 90
- Nucleic acid degradation as barrier to gene delivery : a guide to understand and overcome nuclease activity(2024)
Authors: Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan De Smedt, Katrien Remaut
Pages: 317 - 360 - Repositioning the antihistamine ebastine as an intracellular siRNA delivery enhancer(2023)
Authors: Cristina Muntean, Eva Blondeel, Laure Harinck, Kunal Pednekar, Jai Prakash, Olivier De Wever, Jeanne Leblond Chain, Stefaan De Smedt, Katrien Remaut, Koen Raemdonck
- Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions(2023)
Authors: Helena Braet, Peter-Paul Fransen, Yong Chen, Simon Van Herck, Remco Mariën, Valérie Vanhoorne, Wim Ceelen, Annemieke Madder, Steven Ballet, Richard Hoogenboom, et al.
Pages: 138 - 150 - The effect of electrostatic high pressure nebulization on the stability, activity and ex vivo distribution of ionic self-assembled nanomedicines(2023)
Authors: Helena Braet, Valentina Andretto, Remco Mariën, Beyza Yücesan, Stefan van der Vegte, Ragna Haegebaert, Giovanna Lollo, Stefaan De Smedt, Katrien Remaut
Pages: 318 - 329 - Dual-modality hafnium oxide nanocrystals for in vivo computed tomography and fluorescence imaging of sentinel lymph nodes(2023)
Authors: Loren Deblock, Benedicte Descamps, Ilia Goemaere, Eline Goossens, Glenn Vergauwen, Jens Debacker, Philippe Tummers, Katrien Remaut, Isabel Van Driessche, Klaartje De Buysser, et al.
Pages: 8883 - 8896 - CO2-driven nebulization of pH-sensitive supramolecular polymers for intraperitoneal hydrogel formation and the treatment of peritoneal metastasis(2023)
Authors: Helena Braet, Peter-Paul Fransen, Remco Mariën, Giovanna Lollo, Wim Ceelen, Chris Vervaet, Lieve Balcaen, Frank Vanhaecke, Christian Vanhove, Stefan van der Vegte, et al.
Pages: 49022 - 49034 - Every nano-step counts : a critical reflection on do’s and don’ts in researching nanomedicines for retinal gene therapy(2023)
Authors: Karen Peynshaert, Joke Devoldere, Katrien Remaut
Pages: 259 - 271 - Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy(2022)
Authors: An-Katrien Minnaert, Loes van Schie, Hendrik Grootaert, Jonas Himpe, Simon Devos, Wannes Weyts, Herlinde De Keersmaecker, Kevin Braeckmans, Katrien Remaut
- Laser-induced nanobubbles safely ablate vitreous opacities in vivo(2022)
Authors: Félix Sauvage, Van Phuc Nguyen, Yanxiu Li, Aranit Harizaj, J. Sebag, Dimitri Roels, Viktor Van Havere, Karen Peynshaert, Ranhua Xiong, Juan Fraire, et al.
Pages: 552 - 559 - Nanoparticle mediated targeting of toll-like receptors to treat colorectal cancer(2022)
Authors: Ragna Haegebaert, Maxime Kempers, Wim Ceelen, Ine Lentacker, Katrien Remaut
Pages: 16 - 30
Patents
1 - 2 of 2