Researcher
Kevin Braeckmans
- Keywords:nanomedicines, biophotonics, medical nanotechnology, drug delivery, microscopy
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Nanophotonics, Nanometrology, In vitro testing, Biopharmaceuticals, Non-clinical studies, Nanomaterials, Medical nanotechnology, Biopharmaceutics, Physical pharmacy
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Aug 1999 → Today
Infrastructure
1 - 4 of 4
- Flanders BioImaging (Consortium partner)
- A multimodal non-linear optical platform for 2l3-photon excitation and 2ndl3rd harmonic imaging deep inside living tissues and animals (Consortium partner)
- Confocal and two-photon Microscope (Consortium coordinator)
- Stimulated Emission Depletion Microscope (Consortium coordinator)
Projects
1 - 10 of 56
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Analysis and prevention of protein particle formation – An approach towards safer antibody drugs in the clinicFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Uncovering the mechanism underlying and consequences of alphaherpesvirus-induced formation of tunneling nanotubes (TNTs)From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE)From1 Jan 2023 → TodayFunding: FWO International research infrastructure (IRI)
- Evaluation of cellular dynamics using automated widefield imagingFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Single-cell ICP-mass spectrometry in the biological sciences: on the way to real-world useFrom1 Nov 2022 → 31 Dec 2022Funding: FWO senior postdoctoral fellowship
- NOn-VIral gene modified STEM cell therapyFrom1 Nov 2022 → TodayFunding: HORIZON.3.1 - European Innovation Council (EIC)
- Selective photoporation of the nuclear envelope to mimic pathological defects and facilitate intranuclear delivery.From1 Oct 2022 → TodayFunding: BOF - mobility
- Cofunding core facility - Ghent Light Microscopy (GLiM)From1 Jul 2022 → TodayFunding: BOF - research organisations
Publications
31 - 40 of 235
- Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger(2021)
Authors: Aranit Harizaj, Filip Van Hauwermeiren, Stephan Stremersch, Herlinde De Keersmaecker, Toon Brans, Juan Fraire, Karolien Grauwen, Ine Lentacker, Mohamed Lamkanfi, Kevin Braeckmans
Pages: 6592 - 6604 - PEGylation of recombinant human deoxyribonuclease I decreases its transport across lung epithelial cells and uptake by macrophages(2021)
Authors: Sohaib Mahri, Eléonore Hardy, Tobias Wilms, Herlinde De Keersmaecker, Kevin Braeckmans, Cynthia Bosquillon, Rita Vanbever
- Detection of ovalbumin amyloid-like fibrils at the oil-water interface in oil-in-water emulsions by spinning disk confocal microscopy(2021)
Authors: Arne Huyst, Herlinde De Keersmaecker, Lomme J. Deleu, Kevin Braeckmans, Jan A. Delcour, Paul Van der Meeren
- Lipoplexes to deliver oligonucleotides in gram-positive and gram-negative bacteria : towards treatment of blood infections(2021)
Authors: Sara Pereira, Rita Sobral Santos, Luís Moreira, Nuno Guimarães, Mariana Gomes, Heyang Zhang, Katrien Remaut, Kevin Braeckmans, Nuno Filipe Azevedo
- Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells(2021)
Authors: Aranit Harizaj, Mike Wels, Laurens Raes, Stephan Stremersch, Glenn Goetgeluk, Toon Brans, Félix Sauvage, Ine Lentacker, Kevin Braeckmans
- Hydrogel-induced cell membrane disruptions enable direct cytosolic delivery of membrane-impermeable cargo(2021)
Authors: Jelter Van Hoeck, Thijs Van de Vyver, Aranit Harizaj, Glenn Goetgeluk, Pieterjan Merckx, Jing Liu, Mike Wels, Félix Sauvage, Herlinde De Keersmaecker, Christian Vanhove, et al.
- Stimuli-responsive nanobubbles for biomedical applications(2021)
Authors: Ranhua Xiong, Ronald X. Xu, Chaobo Huang, Stefaan De Smedt, Kevin Braeckmans
Pages: 5746 - 5776 - Faithful fabrication of biocompatible multicompartmental memomicrospheres for digitally color‐tunable barcoding(2020)
Authors: Guosheng Tang, Long Chen, Zixuan Wang, Shuting Gao, Qingli Qu, Ranhua Xiong, Kevin Braeckmans, Yu Shrike Zhang, Chaobo Huang
- Nanobody click chemistry for convenient site-specific fluorescent labelling, single step immunocytochemistry and delivery into living cells by photoporation and live cell imaging(2020)
Authors: Tim Hebbrecht, Jing Liu, Gaelle Boddin, Chloé Van Leene, Klaas Decoene, Annemieke Madder, Kevin Braeckmans, Jan Gettemans
Pages: 33 - 43 - Surface functionalization with polyethylene glycol and polyethyleneimine improves the performance of graphene-based materials for safe and efficient intracellular delivery by laser-induced photoporation(2020)
Authors: Jing Liu, Chengnan Li, Toon Brans, Aranit Harizaj, Shana Van de Steene, Thomas De Beer, Stefaan De Smedt, Sabine Szunerits, Rabah Boukherroub, Ranhua Xiong, et al.
Patents
1 - 9 of 9
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method to increase the permeability of the plasma membrane of cells and a structure suitable for use in such method (Inventor)
- Method and device to provide a microfluidic flow (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Method and system for dispersion measurements (Inventor)