Researcher
Kian Koh
- Disciplines:Developmental biology, Epigenetics, Stem cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → Today - Department of Development and Regeneration (Department)
Member
From1 Oct 2012 → 31 Mar 2013
Projects
1 - 10 of 15
- Lineage-specific epigenetic regulation by TET1 in the pre-streak mouse embryoFrom1 Jan 2023 → TodayFunding: FWO fellowships
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- The early embryonic function of TET DNA dioxygenases in human neurulation and disease.From1 Oct 2021 → TodayFunding: BOF - projects
- The contribution of TET proteins during global DNA demethylation in epigenetic reprogramming and pluripotency inductionFrom1 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The contribution of TET DNA dioxygenases during global DNA demethylation in epigenetic reprogramming and pluripotency induction.From1 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The IncuCyte S3/Organoid platform for live cell culture imaging and kinetic multiparameter analysis of state-of-the-art 3D organoid models and complex tissue mimicsFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- The interplay of TET1, DNA methylation and vitamin metabolism in neurulation.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Epigenetic interactions of DNA oxygenase TET1 in neural tube closure.From1 Oct 2018 → 1 Oct 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Lineage-specific epigenetic regulation by DNA oxygenase TET1 in the pre-streak mouse embryoFrom1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Closing the neural tube: gene-gene interactions of TET1 and the interplay with nutrient metabolismFrom1 Jan 2018 → 9 Nov 2023Funding: FWO fellowships
Publications
1 - 10 of 20
- Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling(2024)
Authors: Jonathan Chui, Aneta Malesa, Paraskevi ATHANASOULI, Joris Vriens, Kian Koh, Catherine Verfaillie, Frederic Lluis Vinas
- Epigenomic, Genomic, and Environmental Interactions of TET1 in Embryonic Development(2023)
Authors: Ben van der Veer, Kian Koh
- VEGF overexpressed mesoangioblasts enhance urethral and vaginal recovery following simulated vaginal birth in rats(2023)
Authors: Marina Monteiro Carvalho Mori Da, Ben van der Veer, Laura Cattani, Kian Koh, Greetje Vande Velde, Rik Gijsbers, Maarten Albersen, Maurilio Sampaolesi, Jan Deprest
- Dual functions of TET1 in germ layer lineage bifurcation distinguished by genomic context and dependence on 5-methylcytosine oxidation(2023)
Authors: Ben van der Veer, Paraskevi ATHANASOULI, Jonathan Chui, Frederic Lluis Vinas, Kian Koh
Pages: 5469 - 5498 - The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency(2023)
Authors: Paraskevi ATHANASOULI, Ben van der Veer, Tijs Vanhessche, Kian Koh, Vincent Pasque, Catherine Verfaillie, An Zwijsen, Frederic Lluis Vinas
- Extracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditions(2022)
Authors: Laura Yedigaryan, Ben van der Veer, Rik Gijsbers, Kian Koh, Liesbeth De Waele, Gunnar Buyse, Rita Derua, Maurilio Sampaolesi
- Wnt/beta-Catenin Inhibition Disrupts Carboplatin Resistance in Isogenic Models of Triple-Negative Breast Cancer(2021)
Authors: Stijn Moens, Ben van der Veer, Paraskevi ATHANASOULI, Emanuela Elsa Cortesi, Maria Francesca Baietti, Kian Koh, Juan-Jose Ventura, Frédéric Amant, Daniela Annibali, Frederic Lluis Vinas
- Coordination of germ-layer lineage choice by TET1 during primed pluripotency(2020)
Authors: Xinlong Luo, Ben van der Veer, Lei Sun, Michela Bartoccetti, Matteo Giovanni Maria Boretto, Hugo Vankelecom, Rita Khoueiry, Kian Koh
Pages: 598 - 618 - Regulatory dynamics of Tet1 and Oct4 resolve stages of global DNA demethylation and transcriptomic changes in the final phases of reprogramming(2020)
Authors: Michela Bartoccetti, Ben van der Veer, Xinlong Luo, Rita Khoueiry, Manmohan Bajaj, Adrian Janiszewski, Bernard Thienpont, Vincent Pasque, Kian Koh
Pages: 2150 - 2169 - Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening(2019)
Authors: Matteo Giovanni Maria Boretto, Nina Maenhoudt, Xinlong Luo, Aurélie Hennes, Bram Boeckx, Ruben Heremans, Indra Van Zundert, Hilde Brems, Benoit Cox, Marc Ferrante, et al.
Pages: 1041 - 1051