Researcher
Kim De Keersmaecker
- Disciplines:Cancer biology
Affiliations
- Laboratory for Disease Mechanisms in Cancer (Division)
Responsible
From1 Oct 2016 → Today - Laboratory for Disease Mechanisms in Cancer (Division)
Member
From1 Oct 2014 → Today - Department of Human Genetics (Department)
Member
From1 Oct 2013 → 30 Sep 2014 - Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) (Division)
Member
From1 Mar 2009 → 30 Sep 2015
Projects
31 - 40 of 42
- Ribosome defects in cancer.From1 Oct 2015 → TodayFunding: BOF - ZAP BOF mandates
- Ribosome defects in cancerFrom1 Jul 2015 → 31 Dec 2018Funding: ERC - Ideas
- Role of ribosomal protein RPL5 as a tumor suppressor.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project
- Reduction of chemotherapy-related late-term effects via targeted molecular combination therapies at high risk forms of childhood cancer.From1 Jan 2014 → 31 Dec 2015Funding: FWO research project
- A mass spectrometry based approach to unravel the role of the RPL10 R98S mutation in T-cell acute lymphoblastic leukemia.From1 Jan 2014 → 31 Dec 2014Funding: FWO research grant KAN
- Targeted brain quenching in T-cell acute lymphoblastic leukemia.From1 Jan 2013 → 31 Dec 2015Funding: FWO research grant KAN
- Role of ribosome defects in leukemia development.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- How the RPL10 R98S mutation translates T-cell acute lymphoblastic leukemiaFrom1 Oct 2012 → 27 Nov 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of ribosomal defects in cancer.From1 Sep 2012 → 23 Mar 2017Funding: IWT personal funding - strategic basic research grants
- RNA interference identification of relevant novel mutations detected by next generation sequencing in T-cell acute lymphoblastic leukemia.From1 Jan 2012 → 31 Dec 2014Funding: FWO research grant KAN
Publications
1 - 10 of 90
- Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer (12 FEB, 10.1038/s41416-023-02553-y, 2024 )(2024)
Authors: Kim De Keersmaecker, Maarten Lambrecht, Kim Kampen
- Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer(2024)
Authors: Kim De Keersmaecker, Maarten Lambrecht, Kim Kampen
Pages: 568 - 584 - Toward more accurate preclinical glioblastoma modeling: Reverse translation of clinical standard of care in a glioblastoma mouse model.(2024)
Authors: Yani Berckmans, Kim De Keersmaecker, An Coosemans
Pages: 381 - 397 - Drivers of de novo Serine/Glycine synthesis in acute leukemia(2023)
Authors: Paulien Verstraete, Kim De Keersmaecker, Kim Kampen
Pages: 2145 - 2146 - APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells(2023)
Authors: Samantha Zaunz, Lukas Lauwereins, Kim De Keersmaecker, Catherine Verfaillie
Pages: 2052 - 2072 - Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer(2023)
Authors: Elien Heylen, Paulien Verstraete, Linde Van Aerschot, Tom Venken, David Nittner, Anne Uyttebroeck, Heidi Segers, Diether Lambrechts, Jan Cools, Kim De Keersmaecker, et al.
Pages: 1862 - 1878 - Oncogenic drivers and therapeutic targeting of serine and glycine synthesis in cancer(2023)
Authors: Elien Heylen, Kim De Keersmaecker, Kim Kampen
- SNPs Ability to Influence Disease Risk: Breaking the Silence on Synonymous Mutations in Cancer(2022)
Authors: Xander Janssens, Daniele Pepe, Kim De Keersmaecker
Pages: 77 - 96Number of pages: 20 - HEATR3 variants impair nuclear import of uL18 (RPL5) and drive Diamond-Blackfan anemia(2022)
Authors: Kim De Keersmaecker, Veerle Labarque
Pages: 3111 - 3126 - Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping(2022)
Authors: Jolien De Bie, Sofie Demeyer, Jan Cools, Kim De Keersmaecker, Joris Vermeesch, Johan Maertens, Heidi Segers, Lucienne Michaux, Barbara Dewaele
Pages: 548 - 561
Patents
1 - 3 of 3