Researcher
Koen Raemdonck
- Disciplines:Nanobiotechnology, Environmental safety and health of nanotechnology, Nanoscale characterisation, Nanophotonics, Nanotechnology not elsewhere classified, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Other pharmaceutical sciences not elsewhere classified, Compound screening, In vitro testing, Biopharmaceuticals, Non-clinical studies, Molecular medicine, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2004 → Today
Infrastructure
1 - 1 of 1
- Confocal and two-photon Microscope (Consortium partner)
Projects
1 - 10 of 18
- Exploring co-encapsulation of antihistamines and immune checkpoint siRNAs in lipid nanoparticles for cancer immunotherapy.From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Conformationally locked G4-decoy oligonucleotides for selective telomerase inhibition and development of a nucleic acid-based anti-telomerase PROTAC strategyFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Synthesis of modified PNA probes for sequence-selective G-quadruplex photoalkylation.From1 Nov 2021 → TodayFunding: FWO Strategic Basic Research Grant
- REpurposing lung Surfactant Protein B for Inhalation therapy with RNA therapeuticsFrom1 May 2021 → TodayFunding: H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
- Repurposing lung surfactant protein B for inhalation therapy with RNA therapeuticsFrom1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Stimulated emission depletion microscopy (STED): Nanoscopy for innovative research in the life sciencesFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- NANOMED / Colloidally stable nanogel formulations for siRNA deliveryFrom1 Aug 2019 → 31 Jan 2020Funding: BOF - doctoral mandates
- Local immunomodulation of atherosclerosis by CD8+ T-cell based nanomedicinesFrom1 May 2019 → 30 Apr 2022Funding: FWO research project (including WEAVE projects)
- RNA-MAGIC: RNA-based bioMArkers and tarGets In asthma and Chronic Obstructive Pulmonary Disease (COPD)From1 Jan 2019 → TodayFunding: BOF - projects
- Combination cancer therapy by simultaneous delivery of cationic amphiphilic drugs and RNA therapeutics using a polymer delivery platformFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
Publications
61 - 70 of 87
- Unraveling the effects of siRNA carrier systems on cell physiology: a multiparametric approach demonstrated on dextran nanogels(2014)
Authors: Stefaan Soenen, Lynn De Backer, Bella Manshian, Shareen Doak, Koen Raemdonck, Kevin Braeckmans
Pages: 61 - 76 - Lipid and polymer nanoparticles for drug delivery to bacterial biofilms(2014)
Authors: Katrien Forier, Koen Raemdonck, Kevin Braeckmans
Pages: 607 - 623 - Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells(2014)
Authors: Ranhua Xiong, Koen Raemdonck, Karen Peynshaert, Ine Lentacker, Ine De Cock, Andre Skirtach, Kevin Braeckmans
Pages: 6288 - 6296 - The influence of natural pulmonary surfactant on the efficacy of siRNA-loaded dextran nanogels(2013)
Authors: Lynn De Backer, Kevin Braeckmans, Koen Raemdonck
Pages: 1625 - 1638 - Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles(2013)
Authors: Sander AA Kooijmans, Stephan Stremersch, Kevin Braeckmans, An Hendrix, Matthew JA Wood, Raymond M Schiffelers, Koen Raemdonck, Pieter Vader
Pages: 229 - 238 - Transport of nanoparticles in cystic fibrosis sputum and bacterial biofilms by single-particle tracking microscopy(2013)
Authors: Katrien Forier, Anne-Sophie Messiaen, Koen Raemdonck, Hendrik Deschout, Joanna Rejman, Frans De Baets, Hans Nelis, Kevin Braeckmans
Pages: 935 - 949 - Polysaccharide-based nucleic acid nanoformulations(2013)
Authors: Koen Raemdonck, Thomas F Martens, Kevin Braeckmans
Pages: 1123 - 1147 - Development of nanomedicines for the treatment of pulmonary biofilm infections: Insights from advanced fluorescence microscopy studies(2013)Volume: 12
Authors: Katrien Forier, Anne-Sophie Messiaen, Martijn Risseeuw, Hendrik Deschout, Koen Raemdonck, Hans Nelis, Fabienne Danhier, Véronique Préat, Frans De Baets, Kevin Braeckmans
Pages: S31 - S31 - In vivo disassembly of IV administered siRNA matrix nanoparticles at the renal filtration barrier(2013)
Authors: Broes Naeye, Hendrik Deschout, Vicky Caveliers, Benedicte Descamps, Kevin Braeckmans, Christian Vanhove, Tony Lahoutte, Koen Raemdonck
Pages: 2350 - 2358 - Comparison of polymeric siRNA nanocarriers in a murine LPS-activated macrophage cell line: gene silencing, toxicity and off-target gene expression(2012)
Authors: Linda B Jensen, Joscha Griger, Broes Naeye, Amir K Varkouhi, Koen Raemdonck, Raymond Schiffelers, Twan Lammers, Gert Storm, Brian S Sproat, Hanne M Nielsen, et al.
Pages: 669 - 682
Patents
1 - 7 of 7
- MOLECULAR ADJUVANTS FOR ENHANCED CYTOSOLIC DELIVERY OF ACTIVE AGENTS (Inventor)
- PARTICLES COMPRISING SURFACTANT PROTEIN B AND ONE OR MORE LIPIDS (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- PARTICLES COMPRISING SURFACTANT PROTEIN B AND ONE OR MORE LIPIDS (Inventor)
- MOLECULAR ADJUVANTS FOR ENHANCED CYTOSOLIC DELIVERY OF ACTIVE AGENTS (Inventor)
- PARTICLES COMPRISING SURFACTANT PROTEIN B AND ONE OR MORE LIPIDS (Inventor)