Researcher
Lien Spans
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Laboratory for Cytogenetics and Genome Research (Division)
Member
From1 Jan 2017 → 31 Dec 2017 - Laboratory for Genetics of Malignant Disorders (Division)
Member
From1 Jan 2015 → 31 Dec 2016 - Laboratory of Molecular Endocrinology (Division)
Member
From1 Sep 2009 → 31 Dec 2014
Publications
21 - 30 of 31
- Novel insight in mechanisms of Enzalutamide resistance in prostate cancer(2014)
Authors: Stefan Prekovic, Christine Helsen, Lien Spans, Thomas Van den Broeck, Frank Claessens
- Novel insight in mechanisms of Enzalutamide resistance in prostate cancer(2014)
Authors: Stefan Prekovic, Christine Helsen, Lien Spans, Thomas Van den Broeck, Frank Claessens
- A satellite-cell specific knockout of the androgen receptor reveals myostatin as a direct androgen target in skeletal muscle(2014)
Authors: Vanessa Dubois, Michaël Laurent, Mieke Sinnesael, Nele Cielen, Christine Helsen, Liesbeth Clinckemalie, Lien Spans, Ghislaine Gayan-Ramirez, Louise Deldicque, Peter Hespel, et al.
Pages: 2979 - 2994 - Androgen Regulation of the TMPRSS2 Gene and the Effect of a SNP in an Androgen Response Element(2013)
Authors: Liesbeth Clinckemalie, Lien Spans, Vanessa Dubois, Michaël Laurent, Christine Helsen, Steven Joniau, Frank Claessens
Pages: 2028 - 40 - The Transcription Intermediary Factor 1β coactivates the 1 Androgen Receptor(2013)
Authors: Lien Spans, Christine Helsen, Liesbeth Clinckemalie, Vanessa Dubois, Evelyne Lerut, Steven Boonen, Dirk Vanderschueren, Frank Claessens
Pages: 699 - 706 - Selective and Classical Androgen Response Elements in Androgen-Regulated Gene Expression(2013)
Authors: Frank Claessens, Liesbeth Clinckemalie, Christine Helsen, Lien Spans, Vanessa Dubois, Michaël Laurent, Steven Boonen, Dirk Vanderschueren, Zhou Wang
Pages: 13 - 28 - The genomic landscape of prostate cancer(2013)
Authors: Lien Spans, Liesbeth Clinckemalie, Christine Helsen, Dirk Vanderschueren, Steven Boonen, Evelyne Lerut, Steven Joniau, Frank Claessens
Pages: 10822 - 51 - A role for selective androgen response elements in the development of the epididymis and the androgen control of the 5α reductase II gene(2012)
Authors: Stefanie Kerkhofs, Vanessa Dubois, Karel De Gendt, Christine Helsen, Liesbeth Clinckemalie, Lien Spans, Frans Schuit, Steven Boonen, Dirk Vanderschueren, Guido Verhoeven, et al.
Pages: 4360 - 4372 - Variations in the exome of the LNCaP prostate cancer cell line(2012)
Authors: Lien Spans, Zeynep Kalender Atak, Evelyne Lerut, Stein Aerts, Frank Claessens
Pages: 1317 - 27 - Structural basis for nuclear hormone receptor DNA binding(2012)
Authors: Christine Helsen, Stefanie Kerkhofs, Liesbeth Clinckemalie, Lien Spans, Michaël Laurent, Steven Boonen, Dirk Vanderschueren, Frank Claessens
Pages: 411 - 417