Researcher
Lien Van Hoecke
- Disciplines:Molecular and cell biology, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry, Medical biophysics, Virology, Clinical microbiology, Cognitive neuroscience, Infectious diseases, Laboratory medicine, Biophysics
Affiliations
- Department of Biochemistry and microbiology (Department)
Member
From1 May 2019 → 20 Sep 2020 - Department of Biomedical molecular biology (Department)
Member
From9 Jan 2015 → Today
Projects
1 - 3 of 3
- The impact of a SARS-CoV-2 infection on brain pathology and vice versa.From1 Nov 2023 → TodayFunding: FWO fellowships
- The foes and friends among the adaptive immune system in Alzheimer’s diseaseFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- Fine tuning and engaging the immune system to defeat Alzheimer’s disease.From1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
Publications
11 - 20 of 41
- A mouse model of hepatic encephalopathy : bile duct ligation induces brain ammonia overload, glial cell activation and neuroinflammation.(2022)
Authors: Wouter Claeys, Lien Van Hoecke, Anja Geerts, Sander Lefere, Griet Van Imschoot, Elien Van Wonterghem, Bart Ghesquière, Christophe Van Steenkiste
- Anti-inflammatory mesenchymal stromal cell-derived extracellular vesicles improve pathology in Niemann-Pick type C disease(2021)
Authors: Lien Van Hoecke, Caroline Van Cauwenberghe, Verena Boerger, Arnout Bruggeman, Jonas Castelein, Griet Van Imschoot, Elien Van Wonterghem, Robin Dittrich, Wouter Claeys, Junhua Xie, et al.
- Involvement of the choroid plexus in the pathogenesis of Niemann-Pick disease type C(2021)
Authors: Lien Van Hoecke, Caroline Van Cauwenberghe, Kristina Dominko, Griet Van Imschoot, Elien Van Wonterghem, Jonas Castelein, Junhua Xie, Wouter Claeys, Charysse Vandendriessche, Anna Kremer, et al.
- The neurogliovascular unit in hepatic encephalopathy(2021)
Authors: Wouter Claeys, Lien Van Hoecke, Sander Lefere, Anja Geerts, Helena Degroote, Christophe Van Steenkiste
- In vivo therapy with M2e-specific IgG selects for an influenza A virus mutant with delayed matrix protein 2 expression(2021)
Authors: Silvie Van den Hoecke, Marlies Ballegeer, Bram Vrancken, Lei Deng, Emma Job, Lien Van Hoecke, Philippe Lemey, Peter Palese
- Low-grade peripheral inflammation affects brain pathology in the App(NL-G-F)mouse model of Alzheimer's disease(2021)
Authors: Junhua Xie, Nina Gorlé, Charysse Vandendriessche, Griet Van Imschoot, Elien Van Wonterghem, Caroline Van Cauwenberghe, Eef Parthoens, Evelien Van Hamme, Saskia Lippens, Lien Van Hoecke, et al.
- mRNA in cancer immunotherapy : beyond a source of antigen(2021)
Authors: Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Ine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
- mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice(2020)
Authors: Lien Van Hoecke, Rein Verbeke, Dorien De Vlieger, Heleen Dewitte, Sharon Van Nevel, Claus Bachert, Ine Lentacker
Pages: 777 - 787 - Specific targeting of IL-1β activity to CD8+ T cells allows for safe use as a vaccine adjuvant(2020)
Authors: Bram Van Den Eeckhout, Lien Van Hoecke, Niko Kley, Gilles Uzé, Jan Tavernier
- mRNA-based therapeutics to induce immunity against cancer and infectious diseases(2020)
Authors: Lien Van Hoecke
Patents
1 - 2 of 2