Researcher
Lien Van Hoecke
- Disciplines:Molecular and cell biology, Microbiology, Systems biology, Plant biology, Medicinal and biomolecular chemistry, Medical biophysics, Virology, Clinical microbiology, Cognitive neuroscience, Infectious diseases, Laboratory medicine, Biophysics
Affiliations
- Department of Biochemistry and microbiology (Department)
Member
From1 May 2019 → 20 Sep 2020 - Department of Biomedical molecular biology (Department)
Member
From9 Jan 2015 → Today
Projects
1 - 3 of 3
- The impact of a SARS-CoV-2 infection on brain pathology and vice versa.From1 Nov 2023 → TodayFunding: FWO fellowships
- The foes and friends among the adaptive immune system in Alzheimer’s diseaseFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- Fine tuning and engaging the immune system to defeat Alzheimer’s disease.From1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
Publications
21 - 30 of 41
- Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation(2020)
Authors: Laurens Raes, Stephan Stremersch, Juan Fraire, Toon Brans, Glenn Goetgeluk, Stijn De Munter, Lien Van Hoecke, Rein Verbeke, Jelter Van Hoeck, Ranhua Xiong, et al.
- Recombinant viruses delivering the necroptosis mediator MLKL induce a potent antitumor immunity in mice(2020)
Authors: Lien Van Hoecke, Stephanie Riederer, Gerd Sutter, Juan Jose Rojas
- The opposing effect of type I IFN on the T cell response by non-modified mRNA-lipoplex vaccines Is determined by the route of administration(2020)
Authors: Lien Van Hoecke, Marlies Ballegeer, Niek Sanders, Stefaan De Koker
Pages: 373 - 381 - Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells(2019)
Authors: Lien Van Hoecke, Laurens Raes, Stephan Stremersch, Toon Brans, Juan Fraire, Ria Roelandt, Wim Declercq, Peter Vandenabeele, Koen Raemdonck, Kevin Braeckmans, et al.
- Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice(2019)
Authors: Patrick Tjok Joe, Ioanna Christopoulou, Lien Van Hoecke, Bert Schepens, Tine Ysenbaert, Carlo Heirman, Kris Thielemans, Xavier Saelens, Joeri Aerts
- Mx1 in hematopoietic cells protects against Thogoto virus infection(2019)
Authors: Jan Spitaels, Lien Van Hoecke, Kenny Roose, Georg Kochs, Xavier Saelens
- Selective engagement of FcγRIV by a M2e-specific single domain antibody construct protects against influenza A virus infection(2019)
Authors: Dorien De Vlieger, Katja Hoffmann, Inge Van Molle, Wim Nerinckx, Lien Van Hoecke, Marlies Ballegeer, Sarah Creytens, Han Remaut, Hartmut Hengel, Bert Schepens, et al.
- Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy(2018)
Authors: Pieterjan Merckx, Lynn De Backer, Lien Van Hoecke, Roberta Guagliardo, Mercedes Echaide, Pieter Baatsen, Bárbara Olmeda, Jésus Pérez-Gil, Koen Raemdonck
Pages: 236 - 246 - Transiently thermoresponsive acetal polymers for safe and effective administration of Amphotericin B as a vaccine adjuvant(2018)
Authors: Simon Van Herck, Lien Van Hoecke, Benoit Louage, Lien Lybaert, Ruben De Coen, Sabah Kasmi, Aaron P Esser-Kahn, Sunil A David, Lutz Nuhn, Bruno De Geest
Pages: 748 - 760 - Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist(2018)
Authors: Lutz Nuhn, Lien Van Hoecke, Kim Deswarte, Yupeng Li, Stefaan De Koker, Sunil A David, Bruno De Geest
Pages: 643 - 651
Patents
1 - 2 of 2