Researcher
Lies De Groef
- Disciplines:Animal cell and molecular biology, Animal morphology, anatomy and physiology, Animal pathology, Cell death and senescence, Cell signalling, Neurological and neuromuscular diseases, Neurophysiology, Ophthalmology
Affiliations
- Animal Physiology and Neurobiology (Division)
Member
From1 Jun 2012 → Today
Projects
1 - 10 of 28
- Building towards a patent - Exploitation of the killifish R&D platform to combat neurodegenerative diseasesFrom1 Feb 2024 → TodayFunding: IOF - mandates
- In vivo evaluation of the expression kinetics and immunogenicity of lipid nanoparticle mediated messenger RNA and self-amplifying messenger RNA delivery to the retina.From1 Jul 2023 → TodayFunding: Other federal public and semi-governmental institutions
- Neuron-glia biology in neurodegeneration.From1 Oct 2022 → TodayFunding: BOF - ZAP BOF mandates
- Hyperspectral retinal imaging as a novel biomarker for Alzheimer’s disease: towards a better understanding of the underlying pathological changesFrom26 Sep 2022 → TodayFunding: FWO Strategic Basic Research Grant
- 3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MINDFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Imaging the invisible in preclinical models using magnetic particle imagingFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Hyperspectral retinal imaging as a novel diagnostic biomarker for Alzheimer's disease.From1 Jan 2022 → TodayFunding: Private funding of national origin - undefined
- The eye as a window to the brain: tackling neurodegenerative disordersFrom1 Nov 2021 → 31 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of extracellular vesicle-microRNAs in Parkinson’s disease: from critical insights into their role in neuroinflammation towards novel microRNA-based therapiesFrom6 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant, BOF - doctoral mandates
- A killifish R&D platform for therapies improving healthy brain agingFrom1 Oct 2021 → 30 Sep 2023Funding: IOF - technology validation in lab
Publications
31 - 40 of 81
- Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils(2021)
Authors: Lien Veys, Lies De Groef
Pages: 1 - 11 - A novel retinal ganglion cell quantification tool based on deep learning(2021)
Authors: Luca Masin, Marie Claes, Steven Bergmans, Lien Cools, Lien Andries, Lieve Moons, Lies De Groef
- The AppNL-G-F mouse retina is a site for preclinical Alzheimer’s disease diagnosis and research(2021)
Authors: Marjan Vandenabeele, Lien Veys, Sophie Lemmens, Géraldine Gelders, Luca Masin, Bart De Strooper, Ingeborg Stalmans, Lieve Moons, Lies De Groef
- Dynamic Changes in Cell Size and Corresponding Cell Fate After Optic Nerve Injury(2020)
Authors: Veerle Baekelandt, Lies De Groef
- Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury(2020)
Authors: Evy Lefevere, Lien Andries, Inge Van Hove, Lieve Moons, Lies De Groef
Pages: 2643 - 2660 - Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer's disease patients(2020)
Authors: Sophie Lemmens, Jan Van Eijgen, Lies De Groef, Rose Bruffaerts, Mathieu Vandenbulcke, Lieve Moons, Rik Vandenberghe, Ingeborg Stalmans
- Neuroinflammation as driving force for axonal regeneration in the adult mouse visual system: MMP2 as a possible modulator(2020)
Authors: Lien Andries, Lieve Moons, Lies De Groef
- Hyperspectral Imaging and the Retina: Worth the Wave?(2020)
Authors: Sophie Lemmens, Jan Van Eijgen, Julie Jacob, Sinéad Moylett, Lies De Groef, Ingeborg Stalmans
- Single-cell transcriptomics analysis of Akimba retina reveals cell type-specific insights into the pathology of diabetic retinopathy(2020)
Authors: Inge Van Hove, Lies De Groef, Bram Boeckx, Elodie Modave, Diether Lambrechts, Lieve Moons
Pages: 2235 - 2248 - Neuroinflammation and optic nerve regeneration: where do we stand in elucidating underlying cellular and molecular players?(2019)
Authors: Lien Andries, Lies De Groef, Lieve Moons
Pages: 397 - 409