Researcher
Manoj Kumar Gautam
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From5 Jun 2014 → Today
Projects
1 - 3 of 3
- Robotized Human Liver-Mimic 3D Model Platform for Efficient NAFLD and DILI Compound ScreeningFrom1 Jan 2021 → TodayFunding: IOF - technology validation in lab
- Biomaterials Development for an In Vitro Hematopoietic Stem Cell NicheFrom1 Jan 2018 → 1 Jan 2022Funding: BOF - doctoral mandates
- 3D Liver Organoids: Modelling Host Hepatitis B Virus InteractionFrom1 Mar 2015 → 28 Feb 2017Funding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
Publications
1 - 10 of 16
- A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes(2022)
Authors: Manoj Gautam, Tine Tricot, Ruben Boon, Burak Toprakhisar, Catherine Verfaillie
Pages: 702 - 712Number of pages: 11 - Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings(2022)
Authors: Tine Tricot, Hendrik Jan Thibaut, Manoj Gautam, Johan Neyts, Catherine Verfaillie
Number of pages: 12 - HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity(2022)
Authors: Sreya Hillol Ghosh, Tine Tricot, Manoj Gautam, FatemehArefeh Nami, Catherine Verfaillie
Number of pages: 18 - Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages(2021)
Authors: Manoj Gautam, Catherine Verfaillie
Pages: 3285 - 3302Number of pages: 18 - A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model(2021)
Authors: Manoj Gautam, Burak Toprakhisar, Ruben Boon, Tine Tricot, Jolan De Boeck, Adrian Ranga, Francesca Maria Bosisio, Tania Roskams, Catherine Verfaillie
Number of pages: 18 - The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods(2020)
Authors: Manoj Gautam, Bela Schmidt, Catherine Verfaillie
Pages: 2435 - 2461Number of pages: 27 - Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines(2020)
Authors: Ruben Boon, Manoj Gautam, Tine Tricot, Ilaria Elia, Jonathan De Smedt, Guy Eelen, Matthew Bird, Philip Roelandt, Ginevra Doglioni, Matteo Rossi, et al.
Number of pages: 16 - Concomitant delivery of paclitaxel and NuBCP-9 peptide for synergistic enhancement of cancer therapy (vol 14 , pg 1301, 2018)(2018)
Authors: Dikshi Gupta, Manoj Gautam, Priyanka Tyagi, Sumeet Kapoor, Amit Tyagi, Tarani Kanta Barman, Surender Kharbanda, Donald Kufe, Harpal Singh
Pages: 2129 - 2129Number of pages: 1 - In vivo efficacy and pharmacokinetics of bi-aryl oxazolidinone RBx 11760 loaded polylactic acid-polyethylene glycol nanoparticles in mouse hematogenous bronchopneumonia and rat groin abscess caused by Staphylococcus aureus(2018)
Authors: Manoj Gautam
Pages: 1213 - 1225Number of pages: 13 - Concomitant Delivery of Paclitaxel and NuBCP-9 peptide for synergistic enhancement of cancer therapy(2018)
Authors: Dikshi Gupta, Manoj Gautam, Priyanka Tyagi, Sumeet Kapoor, Amit Tyagi, Tarani Kanta Barman, Surender Kharbanda, Donald Kufe, Harpal Singh
Pages: 1301 - 1313Number of pages: 13