Researcher
Manoj Kumar Gautam
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From5 Jun 2014 → 31 Mar 2022
Projects
1 - 3 of 3
- Robotized Human Liver-Mimic 3D Model Platform for Efficient NAFLD and DILI Compound ScreeningFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- Human Stem Cell Derived Liver Cells for Disease Modeling and Whole Organ EngineeringFrom1 Jan 2018 → 20 Sep 2022Funding: BOF - doctoral mandates
- 3D Liver Organoids: Modelling Host Hepatitis B Virus InteractionFrom1 Mar 2015 → 28 Feb 2017Funding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
Publications
1 - 10 of 16
- Human Stem Cell Derived Liver Cells for Disease Modeling and Whole Organ Engineering(2022)
Authors: Burak Toprakhisar, Catherine Verfaillie, Manoj Kumar Gautam, Jennifer Patterson, Hans Van Oosterwyck
- A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes(2022)
Authors: Manoj Kumar Gautam, Tine Tricot, Ruben Boon, Burak Toprakhisar, Catherine Verfaillie
Pages: 702 - 712 - Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings(2022)
Authors: Tine Tricot, Hendrik Jan Thibaut, Kayvan Abbasi, Manoj Kumar Gautam, Johan Neyts, Catherine Verfaillie
- Current Status and Challenges of Human Induced Pluripotent Stem Cell-Derived Liver Models in Drug Discovery(2022)
Authors: Tine Tricot, Catherine Verfaillie, Manoj Kumar Gautam
- HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity(2022)
Authors: Sreya Ghosh, Tine Tricot, Manoj Kumar Gautam, FatemehArefeh Nami, Catherine Verfaillie
- Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages(2021)
Authors: Manoj Kumar Gautam, Catherine Verfaillie
Pages: 3285 - 3302 - A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model(2021)
Authors: Manoj Kumar Gautam, Burak Toprakhisar, Matthias Van Haele, Ruben Boon, Tine Tricot, Jolan De Boeck, Adrian Ranga, Francesca Bosisio, Tania Roskams, Catherine Verfaillie
- The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods(2020)
Authors: Manoj Kumar Gautam, Bela Z Schmidt, Catherine Verfaillie
Pages: 2435 - 2461 - Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines(2020)
Authors: Ruben Boon, Manoj Kumar Gautam, Tine Tricot, Ilaria Elia, Jonathan De Smedt, Guy Eelen, Matthew Bird, Philip Roelandt, Ginevra Doglioni, Matteo Rossi, et al.
- Concomitant delivery of paclitaxel and NuBCP-9 peptide for synergistic enhancement of cancer therapy (vol 14 , pg 1301, 2018)(2018)
Authors: Dikshi Gupta, Manoj Kumar Gautam, Priyanka Tyagi, Sumeet Kapoor, Amit Tyagi, Tarani Kanta Barman, Surender Kharbanda, Donald Kufe, Harpal Singh
Pages: 2129 - 2129
Patents
1 - 1 of 1
- Hydrogels for cell culture (Inventor)