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Researcher
Marine Jean Christophe
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Morphological sciences, Oncology
- See also: Chris Marine (KU Leuven)
Affiliations
- Laboratory for Molecular Cancer Biology (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2017 → Today - VIB-KU Leuven Center for Cancer Biology (Research Center)
Responsible
From1 Jan 2017 → Today - Marine Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory for Molecular Cancer Biology (VIB-KU Leuven) (Division)
Member
From1 Oct 2013 → Today - Department of Human Genetics (Department)
Member
From1 Oct 2009 → 31 Dec 2016
Projects
1 - 10 of 10
- VIB Grant for Marine Lab_Period:2022-01-01-2026-12-31From1 Jan 2022 → TodayFunding: FRI - Project driven research
- Eradicating the minimal residual disease in melanomaFrom1 Jan 2022 → TodayFunding: Other international institutions, not mentioned elsewhere
- International PhD Programme for Medical DoctorsFrom1 Jan 2022 → TodayFunding: Other EU initiatives out of framework
- 4D TUMORMAPFrom1 Jul 2021 → 30 Jun 2022Funding: Other international institutions, not mentioned elsewhere
- Understanding resistance to immune checkpoint inhibitors by mapping the tumor-host ecosystem at single-cell resolution — cellsIMPACT - marie curie individual fellowship Joanna PozniakFrom1 May 2020 → 30 Apr 2022Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- 'Exploring the non-genetic (i.e. ePIgenetic) mechanisms that contribute to therapy Escape in melanoma — EscaPI - Marie curie individual fellowship Aurélie BoussardFrom1 May 2020 → 30 Apr 2022Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Melanoma Research alliance awardFrom1 Jun 2019 → 31 May 2022Funding: Other international institutions, not mentioned elsewhere
- Intra-tumoral heterogeneity in NRAS-driven metastatic melanoma — INHuMAN’ (marie curie individual fellowship voor Karras Panagiotis)From1 Apr 2019 → 31 Mar 2021Funding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Revolutionizing Healthcare by Tracking and Understanding Human Cells during Disease’ — ‘LifeTime’From1 Mar 2019 → 30 Apr 2020Funding: Other EU initiatives out of framework
- VIB Grant for Marine Lab_Period:2017-01-01-2021-12-31From1 Jan 2017 → 31 Dec 2021Funding: FRI - Project driven research
Publications
31 - 40 of 78
- Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors.(2021)
Authors: Jean-Christophe Marine
Pages: 611-628 - Tyrosine-Dependent Phenotype Switching Occurs Early in Many Primary Melanoma Cultures Limiting Their Translational Value.(2021)
Authors: Jasper Wouters, Florian Rambow, Stein Aerts, Jean-Christophe Marine
Pages: 780654 - Long non-coding RNA TINCR suppresses metastatic melanoma dissemination by preventing ATF4 translation.(2021)
Authors: Jean-Christophe Marine
Pages: e50852 - Activation of the integrated stress response confers vulnerability to mitoribosome-targeting antibiotics in melanoma.(2021)
Authors: Roberto Vendramin, Panagiotis Karras, Jean-Christophe Marine
Pages: e20210571 - Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia.(2021)
Authors: Aurelie Bousard, Florian Rambow, Jean-Christophe Marine
Pages: 1204-1223 - Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma.(2021)
Authors: Oskar Marin Bejar, Aljosja Rogiers, Michael Dewaele, Panagiotis Karras, Joanna Pozniak, Nina Van Raemdonck, Dennis Pedri, Diether Lambrechts, Florian Rambow, Jean-Christophe Marine
Pages: 1135-1149.e8 - Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals.(2021)
Authors: Jean-Christophe Marine, Florian Rambow
Pages: 302 - CRISPR screens identify tumor-promoting genes conferring melanoma cell plasticity and resistance.(2021)
Authors: Florian Rambow, Oskar Marin Bejar, Jean-Christophe Marine
Pages: e13466 - Non-genetic mechanisms of therapeutic resistance in cancer.(2020)
Authors: Jean-Christophe Marine
Pages: 743-756 - The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage.(2020)
Authors: Florian Rambow, Jean-Christophe Marine
Pages: 1270
Patents
1 - 9 of 9
- RXR ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- MELANOMA DISEASE STRATIFICATION (Inventor)
- CD36 ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- CD36 ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- MELANOMA DISEASE STRATIFICATION (Inventor)
- RXR ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- CD36 ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)
- MELANOMA DISEASE STRATIFICATION (Inventor)
- RXR ANTAGONISTS FOR USE IN MELANOMA TREATMENT (Inventor)