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Researcher
Mathieu Bollen
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 39
- Phospho-regulation at the crossroads of cell proliferation and DNA-damage controlFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- Coordination of cell-cycle progression and DNA-damage repair by the protein phosphatase-1 regulator NIPP1From1 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Life-course regulators of protein phosphatase-1From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Host cell phosphatases in the life cycle of DNA virusesFrom1 Oct 2020 → TodayFunding: BOF - projects
- Dual function of SDS22 in the biogenesis of protein phosphatase-1 holoenzymesFrom14 Oct 2019 → 14 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Role of histone modifications in the life cycle of AAV2 and recombinant AAV-mediated transgene expressionFrom1 Oct 2019 → 27 Jan 2023Funding: FWO Strategic Basic Research Grant, BOF - doctoral mandates
- Chaperone-mediated biogenesis and activity regulation of protein phosphatase-1From3 Sep 2019 → 10 Jan 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting a timer-integrator of cell checkpoint signaling for mesothelioma therapyFrom1 Jan 2019 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Targeting a timer-integrator of cell checkpoint signaling for mesothelioma therapyFrom1 Jan 2019 → 31 Dec 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Molecular timers of the spindle assembly checkpointFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
Publications
21 - 30 of 113
- Coordination of Timers and Sensors in Cell Signaling(2019)
Authors: Junbin Qian, Lendert Gelens, Mathieu Bollen
- Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics.(2019)
Authors: Monique Beullens, Mathieu Bollen, Aleyde Van Eynde
Pages: 16 - 30 - MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells (vol 35, e00267, 2015)(2018)
Authors: Lijs Beke, Cenk Kig, Joannes TM Linders, Shannah Boens, An Boeckx, Erika van Heerde, Marc Parade, An De Bondt, Ilse Van den Wyngaert, Tarig Bashir, et al.
- The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2(2018)
Authors: Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: 18031 - 18039 - Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation(2018)
Authors: Mathieu Bollen
Pages: 766 - + - KNL1 Binding to PP1 and Microtubules Is Mutually Exclusive(2018)
Authors: Mathieu Bollen
Pages: 1327 - + - A substrate-trapping strategy for protein phosphatase PP1 holoenzymes using hypoactive subunit fusions(2018)
Authors: Dan Wu, Rita Derua, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
Pages: 15152 - 15162 - Overexpression of PP1-NIPP1 limits the capacity of cells to repair DNA double-strand breaks(2018)
Authors: Dan Wu, Monique Beullens, Aleyde Van Eynde, Mathieu Bollen
- A Sephin1-insensitive tripartite holophosphatase dephosphorylates translation initiation factor 2(2018)
Authors: Zander Claes, Mathieu Bollen
Pages: 7766 - 7776 - Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome(2018)
Authors: Mathieu Bollen, Els Henckaerts
Pages: E3529 - E3538