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Researcher
Mathieu Bollen
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today
Projects
11 - 20 of 39
- Influence of Temperature on Cell Cycle ProgressionFrom6 Nov 2017 → 30 Jan 2020Funding: BOF - Doctoral projects
- Interference of protein phosphatase PP1 with the DNA-repair capacityFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Spatiotemporal coordination of mitotic phosphatases by the chromosome-associated scaffold protein RepoManFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Phosphatase-directed targeting of the DNA-repair capacity in cancer.From1 Jan 2017 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Regulation of the protein phosphatase scaffold RepoMan during the cell cycleFrom1 May 2015 → 28 Apr 2020Funding: BOF - Doctoral projects
- Chaperone-guided biogenesis and activity regulation of protein phosphatase-1.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Screening for inhibitors of protein phosphatases that induce mitotic cell death in cancer cellsFrom1 Jan 2015 → 31 Dec 2019Funding: FWO Strategic Basic Research Grant, BOF - Doctoral projects
- SUBSTRATE MAPPING AND ACTIVITY REGULATION OF PP1 HOLOENZYMESFrom1 Oct 2014 → 31 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting mitotic-exit phosphatases for cancer therapy.From1 Oct 2014 → 30 Sep 2019Funding: BOF - Concerted Research Project from 1994
- Targeting epigenetic regulators using bacterial macromolecule delivery.From1 Sep 2014 → 31 Aug 2019Funding: Other international institutions, not mentioned elsewhere
Publications
1 - 10 of 113
- Embryonic NIPP1 Depletion in Keratinocytes Triggers a Cell Cycle Arrest and Premature Senescence in Adult Mice.(2024)
Authors: Marloes Jonkhout, Tijs Vanhessche, Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: S0022-202X - DNA damage-induced allosteric activation of protein phosphatase PP1:NIPP1 through Src kinase-induced circularization of NIPP1(2024)
Authors: Aleyde Van Eynde, Mathieu Bollen
- Emerging roles of the Protein Phosphatase 1 (PP1) in the context of viral infections(2024)
Authors: Mathieu Bollen
- A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions(2023)
Authors: Mathieu Bollen
- A deficiency of PPP1R7 (SDS22) results in a loss of protein phosphatase-1 and is associated with a human neurodevelopmental disease(2023)
Authors: Mathieu Bollen
Pages: 224 - 224 - Substrate mapping and activity regulation of PP1 holoenzymes(2022)
Authors: Dan Wu, Mathieu Bollen, Aleyde Van Eynde
- Protein phosphatase 1: life-course regulation by SDS22 and Inhibitor-3(2022)
Authors: Xinyu Cao, Sarah Lemaire, Mathieu Bollen
Pages: 3072 - 3085 - Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases(2021)
Authors: Mathieu Bollen, Aleyde Van Eynde
- Protein phosphatase 1 regulates atypical mitotic and meiotic division in Plasmodium sexual stages(2021)
Authors: Mathieu Bollen
- Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation(2021)
Authors: Rita Derua, Monique Beullens, Mathieu Bollen
Pages: 834 - 838