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Researcher
Mathieu Bollen
- Disciplines:Systems biology
Affiliations
- Laboratory of Biosignaling & Therapeutics (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Biosignaling & Therapeutics (Division)
Member
From1 Oct 2007 → Today
Projects
31 - 39 of 39
- Implementation of functional imaging and molecular diagnostics for patient-tailored treatment of prostate cancer.From15 Sep 2009 → 30 Jun 2015Funding: Ministery of Social Affairs, Public Health and Environment
- Mitotic function and regulation of the phosphatase scaffold Repo-ManFrom1 Jun 2009 → 28 Mar 2014Funding: Own budget, for example: patrimony, inscription fees, gifts
- Epigenetic control by the proliferation regulator NIPP1.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project
- PolycombGroup targets as DNA methylation biomarkers for improved diagnosis, prognosis and predictor as response to treatment of prostate cancer.From1 Jan 2009 → 30 Sep 2015Funding: Ministery of Social Affairs, Public Health and Environment
- Implementation of functional imaging and molecular diagnostics for patient-tailored treatment of prostate cancer.From1 Jan 2009 → 30 Sep 2015Funding: Ministery of Social Affairs, Public Health and Environment
- Recruitment and activity regulation of the methyltransferase EZH2, an epigenetic key regulator of differentiational genes.From1 Oct 2008 → 20 Nov 2012Funding: FWO fellowships
- Genome-wide promotor binding profiling of Protein phosphatase 1 and its major nuclear targeting subunitsFrom1 Oct 2008 → 30 Sep 2014Funding: BOF - Doctoral projects
- The use of transgenice mice to unravel the in vivo functions of protein phosphatase-1.From1 Oct 2008 → 30 Sep 2014Funding: FWO fellowships
- Genome-wide exploration of the protein phosphatase-1 interactome.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
Publications
1 - 10 of 113
- Embryonic NIPP1 Depletion in Keratinocytes Triggers a Cell Cycle Arrest and Premature Senescence in Adult Mice.(2024)
Authors: Marloes Jonkhout, Tijs Vanhessche, Iris Verbinnen, Aleyde Van Eynde, Mathieu Bollen
Pages: S0022-202X - DNA damage-induced allosteric activation of protein phosphatase PP1:NIPP1 through Src kinase-induced circularization of NIPP1(2024)
Authors: Aleyde Van Eynde, Mathieu Bollen
- Emerging roles of the Protein Phosphatase 1 (PP1) in the context of viral infections(2024)
Authors: Mathieu Bollen
- A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions(2023)
Authors: Mathieu Bollen
- A deficiency of PPP1R7 (SDS22) results in a loss of protein phosphatase-1 and is associated with a human neurodevelopmental disease(2023)
Authors: Mathieu Bollen
Pages: 224 - 224 - Substrate mapping and activity regulation of PP1 holoenzymes(2022)
Authors: Dan Wu, Mathieu Bollen, Aleyde Van Eynde
- Protein phosphatase 1: life-course regulation by SDS22 and Inhibitor-3(2022)
Authors: Xinyu Cao, Sarah Lemaire, Mathieu Bollen
Pages: 3072 - 3085 - Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases(2021)
Authors: Mathieu Bollen, Aleyde Van Eynde
- Protein phosphatase 1 regulates atypical mitotic and meiotic division in Plasmodium sexual stages(2021)
Authors: Mathieu Bollen
- Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation(2021)
Authors: Rita Derua, Monique Beullens, Mathieu Bollen
Pages: 834 - 838