Researcher
Nicky Helsen
- Disciplines:Genetics, Systems biology, Molecular and cell biology
Affiliations
- Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 31 Dec 2016
Projects
1 - 1 of 1
- Use of optimized pluripotent stem cell derived hepatocytes for evaluation of the biology of viral replication of hepatitis viruses.From1 Sep 2012 → 31 Dec 2016Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 13
- Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals(2018)
Authors: Tine Tricot, Nicky Helsen, Suzanne Kaptein, Johan Neyts, Catherine Verfaillie
- Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells(2018)
Authors: Philip Roelandt, Manoj Kumar Gautam, Manmohan Bajaj, Nicky Helsen, Conny Gysemans, Catherine Verfaillie
- Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition(2018)
Authors: Laura Ordovas Vidal, Ruben Boon, Elena Pistoni, Yemiao Chen, Esther Wolfs, Wenting Guo, Rangarajan Sambathkumar, Sylwia Bobis-Wozowicz, Nicky Helsen, Jolien Vanhove, et al.
Pages: 673 - Molecular imaging of human embryonic stem cells stably expressing human PET reporter genes after zinc finger nucleases-mediated genome editing(2017)
Authors: Esther Wolfs, Bryan Holvoet, Laura Ordovas Vidal, Natacha Breuls, Nicky Helsen, Matthias Schönberger, Susanna Raitano, Tom Struys, Hubert Vanbilloen, Cindy Casteels, et al.
Pages: 1659 - 1665 - Molecular imaging of human embryonic stem cells stably expressing human PET reporter genes after zinc finger nucleases-mediated genome editing(2017)
Authors: Esther Wolfs, Bryan Holvoet, Laura Ordovas Vidal, Natacha Breuls, Nicky Helsen, Matthias Schönberger, Susanna Raitano, Tom Struys, Cindy Casteels, Maurilio Sampaolesi, et al.
Pages: 1659 - 1665 - Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate(2017)
Authors: Elena Pistoni, Nicky Helsen, Jolien Vanhove, Ruben Boon, Zhuofei Xu, Laura Ordovas Vidal, Catherine Verfaillie
Pages: 0186884 - Infection of stem cell-derived hepatocytes with hepatotropic viruses(2016)
Authors: Nicky Helsen, Catherine Verfaillie, Jan Paeshuyse, Johan Neyts
- Rapid and Efficient Generation of Recombinant Human Pluripotent Stem Cells by Recombinase-mediated Cassette Exchange in the AAVS1 Locus(2016)
Authors: Laura Ordovas Vidal, Ruben Boon, Elena Pistoni, Yemiao Chen, Rangarajan Sambathkumar, Nicky Helsen, Jolien Vanhove, Kim Vanuytsel, Susanna Raitano, Catherine Verfaillie
- H3K27me3 does not orchestrate the expression of lineage-specific markers in hesc-derived hepatocytes in vitro(2016)
Authors: Jolien Vanhove, Elena Pistoni, Kristel Eggermont, Nicky Helsen, Ruben Boon, Catherine Verfaillie
Pages: 192 - 206 - Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication(2016)
Authors: Nicky Helsen, Yannick Debing, Jan Paeshuyse, Kai Dallmeier, Ruben Boon, Christel Claes, Johan Neyts, Catherine Verfaillie
Pages: 565 - 573