Researcher
Olivier Vanakker
- Keywords:paediatric genetics, soft tissue mineralisation, syndromology, molecular genetics, pathophysiological mechanisms, calcification diseases, pseudoxanthoma elasticum, clinical genetics, dysmorphology, ectopic mineralisation diseases, stroke, cerebrovascular diseases
- Disciplines:Paediatrics and neonatology not elsewhere classified, Clinical genetics and molecular diagnostics, Neonatology, Epigenetics, Immunogenetics, Paediatrics, Genetics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2003 → 30 Sep 2018
Projects
1 - 9 of 9
- International thematic network INTEC (ectopic calcifiaction)From1 Jan 2023 → TodayFunding: BOF - mobility
- Study of DDR/PARP1 signaling in the pathogenesis and treatment of soft tissue mineralization, using pseudoxanthoma elasticum as a model.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Identifying mechanisms of disease variability in soft tissue mineralization disorders, using pseudoxanthoma elasticum as a modelFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Natural history and determinants of the burden of medial vascular calcification, using pseudoxanthoma elasticum as a model.From1 Nov 2020 → 30 Sep 2023Funding: FWO fellowships
- Natural history and determinants of the burden of medial vascular calcification, using pseudoxanthoma elasticum as a model.From1 Oct 2019 → 31 Oct 2020Funding: BOF - doctoral mandates
- An integrated approach towards understanding and treating soft tissue mineralization, with pseudoxanthoma elasticum as a model.From1 Jan 2015 → 31 Oct 2019Funding: BOF - Doctoral projects
- Unraveling the ophthalmological phenotype and etiopathogenetic mechanisms in pseudoxanthoma elasticumFrom1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships, BOF - Other initiatives
- Study of the cardiovascular phenotype and etiopathogenetic mechanisms in pseudoxanthoma elasticum.From1 Oct 2013 → TodayFunding: FWO fellowships
Publications
31 - 40 of 120
- From membrane to mineralization : the curious case of the ABCC6 transporter(2020)
Authors: Lukas Nollet, Olivier Vanakker
Pages: 4109 - 4133 - Cellular and molecular biomarkers indicate premature aging in pseudoxanthoma elasticum patients(2020)
Authors: Janina Tiemann, Thomas Wagner, Olivier Vanakker, Jose-Luis Bueno Cabrera, Bettina Ibold, Isabel Faust, Cornelius Knabbe, Doris Hendig
Pages: 536 - 546 - Severe early-onset manifestations of pseudoxanthoma elasticum resulting from the cumulative effects of several deleterious mutations in ENPP1, ABCC6 and HBB : transient improvement in ectopic calcification with sodium thiosulfate(2020)
Authors: L. Omarjee, Y. Nitschke, E. Bourrat, M. D. Vignon, N Navasiolava, G. Leftheriotis, G. Kauffenstein, F. Rutsch, Olivier Vanakker, L. Martin
Pages: 367 - 372 - Endogenous calcification inhibitors in the prevention of vascular calcification : a consensus statement from the COST Action EuroSoftCalcNet(2019)
Authors: Magnus Bäck, Tamas Aranyi, M Leonor Cancela, Miguel Carracedo, Natércia Conceição, Georges Leftheriotis, Vicky Macrae, Ludovic Martin, Yvonne Nitschke, Andreas Pasch, et al.
- Generation and validation of the first complete knockout model of abcc6a in zebrafish(2019)Volume: 27
Authors: Matthias Van Gils, Andy Willaert, Eva De Vilder, Paul Coucke, Olivier Vanakker
Pages: 93 - 93 - A likely pathogenic variant in the SLC20A2 gene presenting with progressive myoclonus(2019)
Authors: Simon Lamquet, Eliana M Ramos, Andrea Legati, Giovanni Coppola, Dimitri Hemelsoet, Olivier Vanakker
Pages: 605 - 609 - Plasma inorganic pyrophosphate and alkaline phosphatase in patients with pseudoxanthoma elasticum(2019)
Authors: Ana María Sánchez-Tévar, María García-Fernández, Belén Murcia-Casas, José Rioja-Villodres, Juan Luis Carrillo, Marta Camacho, Matthias Van Gils, Miguel Angel Sánchez-Chaparro, Olivier Vanakker, Pedro Valdivielso
- Non-invasive prenatal testing (NIPT) : how to handle secondary findings of maternal chromosomal abnormalities(2019)Volume: 27
Authors: Machteld Baetens, Tom Sante, Sarah Vergult, M. De Smet, S. Janssens, Olivier Vanakker, Bert Callewaert, Bruce Poppe, Annelies Dheedene, Björn Menten
Pages: 24 - 24 - Morpholino-mediated gene knockdown in zebrafish : it is all about dosage and validation(2019)
Authors: Olivier Vanakker
Pages: 1599 - 1600 - The inflammasome pathway is involved in PXE through IL1B upregulation in patients with a severe cardiovascular PXE phenotype(2019)Volume: 27
Authors: Eva De Vilder, L. Martin, G. Leftheriotis, Paul Coucke, Anne De Paepe, Filip Van Nieuwerburgh, Olivier Vanakker
Pages: 124 - 125