Researcher
Olivier Vanakker
- Keywords:paediatric genetics, soft tissue mineralisation, syndromology, molecular genetics, pathophysiological mechanisms, calcification diseases, pseudoxanthoma elasticum, clinical genetics, dysmorphology, ectopic mineralisation diseases, stroke, cerebrovascular diseases
- Disciplines:Paediatrics and neonatology not elsewhere classified, Clinical genetics and molecular diagnostics, Neonatology, Epigenetics, Immunogenetics, Paediatrics, Genetics
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2003 → 30 Sep 2018
Projects
1 - 9 of 9
- International thematic network INTEC (ectopic calcifiaction)From1 Jan 2023 → TodayFunding: BOF - mobility
- Study of DDR/PARP1 signaling in the pathogenesis and treatment of soft tissue mineralization, using pseudoxanthoma elasticum as a model.From1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Identifying mechanisms of disease variability in soft tissue mineralization disorders, using pseudoxanthoma elasticum as a modelFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Natural history and determinants of the burden of medial vascular calcification, using pseudoxanthoma elasticum as a model.From1 Nov 2020 → 30 Sep 2023Funding: FWO fellowships
- Natural history and determinants of the burden of medial vascular calcification, using pseudoxanthoma elasticum as a model.From1 Oct 2019 → 31 Oct 2020Funding: BOF - doctoral mandates
- An integrated approach towards understanding and treating soft tissue mineralization, with pseudoxanthoma elasticum as a model.From1 Jan 2015 → 31 Oct 2019Funding: BOF - Doctoral projects
- Unraveling the ophthalmological phenotype and etiopathogenetic mechanisms in pseudoxanthoma elasticumFrom1 Oct 2014 → 30 Sep 2018Funding: FWO fellowships, BOF - Other initiatives
- Study of the cardiovascular phenotype and etiopathogenetic mechanisms in pseudoxanthoma elasticum.From1 Oct 2013 → TodayFunding: FWO fellowships
Publications
41 - 50 of 120
- Cellular signaling in pseudoxanthoma elasticum : an update(2019)
Authors: Lukas Nollet, Ewout Verly, Nancy Deianova, Olivier Vanakker
Pages: 119 - 129 - Targeted compound screening for PXE using CRISPR/Cas9 abcc6a mutant zebrafish model(2019)
Authors: Olivier Vanakker
Number of pages: 1 - Internal carotid artery hypoplasia : a new clinical feature in pseudoxanthoma elasticum(2019)
Authors: Loukman Omarjee, Jacques-Olivier Fortrat, Antoine Larralde, Estelle Le Pabic, Gilles Kauffenstein, Maxence Laot, Nastassia Navasiolava, Pierre-Jean Mention, Juan Luis Carrillo Linares, Pedro Valdivielso, et al.
Pages: 108 - 111 - Comprehensive re-assessment of causality of ABCC6 missense variants associated with pseudoxanthoma elasticum(2019)Volume: 27
Authors: Shana Verschuere, Paul Coucke, Olivier Vanakker
Pages: 1269 - 1270 - The role of vitamin K and its related compounds in Mendelian and acquired ectopic mineralization disorders(2019)
Authors: Lukas Nollet, Matthias Van Gils, Shana Verschuere, Olivier Vanakker
- Generation and validation of the first complete knockout model of ABCC6A in zebrafish(2018)
Authors: Olivier Vanakker
Number of pages: 1 - Interpreting genetic variants in titin in patients with muscle disorders(2018)
Authors: Marco Savarese, Lorenzo Maggi, Anna Vihola, Per Harald Jonson, Giorgio Tasca, Lucia Ruggiero, Luca Bello, Francesca Magri, Teresa Giugliano, Annalaura Torella, et al.
Pages: 557 - 565 - Generation and validation of a complete knockout model of abcc6a in zebrafish(2018)
Authors: Eva De Vilder, Olivier Vanakker
Pages: 2333 - 2342 - De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation(2018)
Authors: M. Felicia Basilicata, Ange-Line Bruel, Giuseppe Semplicio, Claudia Isabelle Keller Valsecchi, Tugçe Aktas, Yannis Duffourd, Tobias Rumpf, Jenny Morton, Iben Bache, Witold G. Szymanski, et al.
Pages: 1442 - 1451 - A Belgian consensus strategy to identify familial hypercholesterolaemia in the coronary care unit and its subsequent cascade screening and treatment : BEL-FaHST (The BELgium Familial Hypercholesterolaemia STrategy)(2018)
Authors: Olivier S Descamps, Olivier Van Caenegem, Michel P Hermans, Jean-Luc Balligand, Christophe Beauloye, Antoine Bondue, Stephane Carlier, Emilie Castermans, Fabien Chenot, Marc Claeys, et al.
Pages: 369 - 376