Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 56
- Harnessing lysosomal iron homeostasis to prevent melanoma disseminationFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Function of PERK in T cell metabolic reprogramming: deciphering its role as ER stress sensor vs its novel role as coordinator of membrane contact sitesFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Understanding the spatio-temporal changes of the metastatic lymph node epicenterFrom11 Apr 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding and tackling the spatio-temporal changes of the metastatic lymph node epicenterFrom1 Jan 2022 → TodayFunding: FWO EOS
- Unfolding the role of Perk in T cell biology and metabolism: a matter of contact sites?From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- DIPITO: valorisation of deep immune profiling and novel immunotherapeutics for oncology.From1 Oct 2021 → TodayFunding: IOF - mandates
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Clinical, Immunological and Functional Study of ADA2 deficiencyFrom2 Aug 2021 → TodayFunding: FWO fellowships
- Autophagy in inflammation and inflammatory disorders (ATLANTIS), from basic insights to experimental therapy.From1 Jan 2021 → TodayFunding: BOF - iBOF
Publications
1 - 10 of 237
- SECRETED APOE REWIRES MELANOMA CELL STATE VULNERABILITY TO FERROPTOSIS(2024)
Authors: Sanket More, Patrizia Agostinis
- Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.(2024)
Authors: Yingli Zhu, Yoke Chin Chai, Patrizia Agostinis, Johan Swinnen
Pages: 6 - Decoding immunogenic cell death from a dendritic cell perspective(2024)
Authors: Patrizia Agostinis
Pages: 350 - 370 - Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2023)
Authors: Francesca Rizzollo, Johan Van Weyenbergh, Oliver Bechter, Francesca Bosisio, Diether Lambrechts, Gabriele Bergers, Patrizia Agostinis
- REVERSE TRANSLATIONAL DESIGNING OF THE NEXT-GENERATION ANTICANCER DC VACCINATIONS: Mechanisms and beyond(2023)
Authors: Jenny Sprooten, Abhishek Garg, Susan Schlenner, Patrizia Agostinis
- Cellular and molecular features related to exceptional therapy response and extreme long-term survival in glioblastoma(2023)
Authors: Maxime Vanmechelen, Paul Clement, Jean-françois Daisne, Isabelle Vanden Bempt, Raf Sciot, Abhishek Garg, Patrizia Agostinis, Frederik De Smet, Steven De Vleeschouwer
Pages: 11107 - 11126 - Apoptotic cell death in disease-Current understanding of the NCCD 2023(2023)
Authors: Patrizia Agostinis, Bart De Strooper, Abhishek Garg, Chris Marine
Pages: 1097 - 1154 - Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.
- Eating your own fat to stay fit: lipophagy sustains lymphangiogenesis(2023)
Authors: Diede Houbaert, Patrizia Agostinis
Pages: 1351 - 1353 - PERK recruits E-Syt1 at ER-mitochondria contacts for mitochondrial lipid transport and respiration(2023)
Authors: Maria Livia Sassano, Alex van Vliet, Chris Van den Haute, Johan Swinnen, Leen Moens, Kristina Casteels, Isabelle Meyts, Patrizia Agostinis