Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 56
- Harnessing lysosomal iron homeostasis to prevent melanoma disseminationFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Function of PERK in T cell metabolic reprogramming: deciphering its role as ER stress sensor vs its novel role as coordinator of membrane contact sitesFrom1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Understanding the spatio-temporal changes of the metastatic lymph node epicenterFrom11 Apr 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Understanding and tackling the spatio-temporal changes of the metastatic lymph node epicenterFrom1 Jan 2022 → TodayFunding: FWO EOS
- Unfolding the role of Perk in T cell biology and metabolism: a matter of contact sites?From1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- DIPITO: valorisation of deep immune profiling and novel immunotherapeutics for oncology.From1 Oct 2021 → TodayFunding: IOF - mandates
- Inter-organelle communication through membrane contact sites in oncology and neurodegenerative diseases (InterAction)From1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Clinical, Immunological and Functional Study of ADA2 deficiencyFrom2 Aug 2021 → TodayFunding: FWO fellowships
- Autophagy in inflammation and inflammatory disorders (ATLANTIS), from basic insights to experimental therapy.From1 Jan 2021 → TodayFunding: BOF - iBOF
Publications
21 - 30 of 239
- Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting(2022)
Authors: Nicole Rufo, Rita Derua, Abhishek Garg, Michael Dewaele, Peter de Witte, Steven Verhelst, Patrizia Agostinis
Pages: 230 - 245 - The lysosome as a master regulator of iron metabolism(2021)
Authors: Francesca Rizzollo, Peter Vangheluwe, Patrizia Agostinis
Pages: 960 - 975 - Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer(2021)
Authors: Jenny Sprooten, Ann Vankerckhoven, Isaure Vanmeerbeek, Yani Berckmans, Roxanne Wouters, Thaïs Baert, Tom Bourne, Wouter Froyman, Dominique Schols, Patrizia Agostinis, et al.
- BNIP3 in melanoma: isn't it IRONic?(2021)
Authors: Patrizia Agostinis
- Endothelial cell autophagy in homeostasis and cancer(2021)
Authors: Jelle Verhoeven, Jef Baelen, Madhur Agrawal, Patrizia Agostinis
Pages: 1497 - 1511 - BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis(2021)
Authors: Matteo Rossi, Chris Van den Haute, Maria Livia Sassano, Abhishek Garg, Francesca Bosisio, Jasper Wouters, Peter Vangheluwe, Wim Annaert, Johan Swinnen, Joost van den Oord, et al.
- BNIP3 IN MELANOMA: SITTING ON THE IRON THRONE Unraveling the role of BNIP3 in mitochondrial homeostasis, metabolism and melanoma growth(2021)
Authors: Mónica Vara Pérez, Patrizia Agostinis, Wim Annaert
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(2021)
Authors: Patrizia Agostinis, Geert Bultynck, Abhishek Garg, Manosij Ghosh, Jan Gunst, Muxing Guo, Peter Hoet, Bella Manshian, Jan Parys, Stefaan Soenen, et al.
Pages: 1 - 382 - ATP13A3 is a major component of the enigmatic mammalian polyamine transport system(2021)
Authors: Norin Hamouda, Chris Van den Haute, Roeland Vanhoutte, Johan Swinnen, Patrizia Agostinis, Veerle Baekelandt, Wim Annaert, Steven Verhelst, Jan Eggermont, Peter Vangheluwe
- Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis(2021)
Authors: Patrizia Agostinis