Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
11 - 20 of 56
- Evaluating the Role of Autophagy in the Tumor Vasculature and as Anti-angiogenic Escape MechanismFrom1 Oct 2020 → 30 Sep 2021Funding: BOF - postdoctoral mandates
- Integration of complementary, high throughput single-cell omics with spatial resolution.From1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- A kinetic, high-throughput cellular screening system (Plate Imaging Reader) for the "real time" monitoring of dynamic intracellular Ca2+ signals in living cellsFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- Therapeutic harnessing of iron-dependent cell death in melanoma; the ApolipoproteinE and ferroptosis linkFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- Screening of Hyp-PDT induced ICD-sensitive GBM Immunophenotype and Exploration of Synergetic Effect of Sonodynamic Therapy in GBM ImmunotherapyFrom2 Dec 2019 → 2 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting cancer cell’s plasticity and drug-resistance by the induction of ferroptosisFrom1 Nov 2019 → TodayFunding: FWO fellowships
- SAFE ADVISOR : Selection and Assignment For an Exploratory, Adjustible Vaccine through Immune Stratification for brain cancer.From1 Oct 2019 → 30 Sep 2023Funding: Foundations, funds and other with scientific goal
- Harnessing autophagy in the tumor microenvironment for the improvement of radiation mediated anti-tumor immunityFrom1 Jan 2019 → 31 Dec 2021Funding: Foundations, funds and other with scientific goal
- Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma.From1 Oct 2018 → 29 Mar 2024Funding: FWO fellowships
- REVERSE TRANSLATIONAL DESIGNING OF THE NEXT-GENERATION ANTICANCER DC VACCINATIONS: Mechanisms and beyondFrom22 Aug 2018 → 10 Oct 2023Funding: BOF - doctoral mandates, Foundations, funds and other with scientific goal
Publications
1 - 10 of 238
- An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.(2024)
Authors: Gabriele Bergers, Patrizia Agostinis
Pages: 114020 - SECRETED APOE REWIRES MELANOMA CELL STATE VULNERABILITY TO FERROPTOSIS(2024)
Authors: Sanket More, Patrizia Agostinis
- Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.(2024)
Authors: Yingli Zhu, Yoke Chin Chai, Patrizia Agostinis, Johan Swinnen
Pages: 6 - Decoding immunogenic cell death from a dendritic cell perspective(2024)
Authors: Patrizia Agostinis
Pages: 350 - 370 - Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2023)
Authors: Francesca Rizzollo, Johan Van Weyenbergh, Oliver Bechter, Francesca Bosisio, Diether Lambrechts, Gabriele Bergers, Patrizia Agostinis
- REVERSE TRANSLATIONAL DESIGNING OF THE NEXT-GENERATION ANTICANCER DC VACCINATIONS: Mechanisms and beyond(2023)
Authors: Jenny Sprooten, Abhishek Garg, Susan Schlenner, Patrizia Agostinis
- Cellular and molecular features related to exceptional therapy response and extreme long-term survival in glioblastoma(2023)
Authors: Maxime Vanmechelen, Paul Clement, Jean-françois Daisne, Isabelle Vanden Bempt, Raf Sciot, Abhishek Garg, Patrizia Agostinis, Frederik De Smet, Steven De Vleeschouwer
Pages: 11107 - 11126 - Apoptotic cell death in disease-Current understanding of the NCCD 2023(2023)
Authors: Patrizia Agostinis, Bart De Strooper, Abhishek Garg, Chris Marine
Pages: 1097 - 1154 - Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.
- Eating your own fat to stay fit: lipophagy sustains lymphangiogenesis(2023)
Authors: Diede Houbaert, Patrizia Agostinis
Pages: 1351 - 1353