Researcher
Patrizia Agostinis
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Cell death, Cell signalling, Cancer therapy
Affiliations
- Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Responsible
From1 Jan 2012 → Today - Agostinis Lab (Research group)
Responsible
From1 Mar 2019 → Today - Laboratory of Cell Death Research & Therapy (VIB-KU Leuven) (Division)
Member
From1 Oct 2007 → Today
Projects
21 - 30 of 56
- A nanoscopy platform for live cell and tissue imaging based on adaptive illumination and spatial light modulationFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- Understanding intra-tumor heterogeneity and its implication in therapeutic resistance with spatial transcriptomics in space and timeFrom1 Jan 2018 → 1 Jan 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Refining cancer cell death and danger signals for the improvement of immunotherapyFrom1 Jan 2018 → 31 Dec 2021Funding: FWO EOS
- Role of lymphatic endothelial cell-associated autophagy in melanoma disseminationFrom11 Sep 2017 → 28 Sep 2023Funding: BOF - Doctoral projects, FWO fellowships
- Deciphering the role of a novel endoplasmic reticulum associated protein complex in inter-organellar communication and calcium fluxesFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Harnessing autophagy in the tumour stroma to improve anti-tumour immunityFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- ER-MITOCHONDRIA CONTACT SITES-MEDIATED LIPID TRANSFER: AT THE CROSSROAD BETWEEN LIFE AND DEATHFrom28 Oct 2016 → 16 Nov 2022Funding: BOF - doctoral mandates
- Addition of ImageStream facilities to the FACS CoreFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- Role of combined chemo- and immunotherapy in early breast cancerFrom1 Oct 2016 → 30 Sep 2020Funding: Nonprofit institution or equivalents
- The impact of autophagy-driven intercellular communication in melanoma vasculature to restrain T cell-mediated anticancer immunityFrom1 Oct 2016 → 30 Jun 2019Funding: FWO fellowships
Publications
1 - 10 of 239
- Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2024)
Authors: Jelle Verhoeven, Patrizia Agostinis, Madhur Agrawal, Sandra Nuyts
- An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.(2024)
Authors: Gabriele Bergers, Patrizia Agostinis
Pages: 114020 - SECRETED APOE REWIRES MELANOMA CELL STATE VULNERABILITY TO FERROPTOSIS(2024)
Authors: Sanket More, Patrizia Agostinis
- Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.(2024)
Authors: Yingli Zhu, Yoke Chin Chai, Patrizia Agostinis, Johan Swinnen
Pages: 6 - Decoding immunogenic cell death from a dendritic cell perspective(2024)
Authors: Patrizia Agostinis
Pages: 350 - 370 - Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2023)
Authors: Francesca Rizzollo, Johan Van Weyenbergh, Oliver Bechter, Francesca Bosisio, Diether Lambrechts, Gabriele Bergers, Patrizia Agostinis
- REVERSE TRANSLATIONAL DESIGNING OF THE NEXT-GENERATION ANTICANCER DC VACCINATIONS: Mechanisms and beyond(2023)
Authors: Jenny Sprooten, Abhishek Garg, Susan Schlenner, Patrizia Agostinis
- Cellular and molecular features related to exceptional therapy response and extreme long-term survival in glioblastoma(2023)
Authors: Maxime Vanmechelen, Paul Clement, Jean-françois Daisne, Isabelle Vanden Bempt, Raf Sciot, Abhishek Garg, Patrizia Agostinis, Frederik De Smet, Steven De Vleeschouwer
Pages: 11107 - 11126 - Apoptotic cell death in disease-Current understanding of the NCCD 2023(2023)
Authors: Patrizia Agostinis, Bart De Strooper, Abhishek Garg, Chris Marine
Pages: 1097 - 1154 - Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.