Researcher
Paul Coucke
- Disciplines:Genetically modified animals
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2002 → 30 Sep 2018
Projects
1 - 10 of 13
- Discovery of genetic modifiers of the phenotypical cardiovascular variability in Marfan syndrome to pave the road to individualized treatment protocols.From1 Nov 2024 → TodayFunding: BOF - doctoral mandates
- Identification of molecular mechanisms involved in Osteogenesis ImperfectaFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- Identification of modifier genes responsible for the phenotypic variability in Osteogenesis Imperfecta (OI)- patients using zebrafish modelsFrom14 Feb 2024 → TodayFunding: BOF - doctoral mandates
- Nuclear Transfer for female-related infertility and mitochondrial diseasesFrom1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Unravelling the mitochondrial DNA reversion phenomenonFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Cofunding core facility - Core Zebrafish Facility Ghent (Core ZFG)From1 Jul 2022 → TodayFunding: BOF - research organisations
- Comparison of editing, complementing or replacement of defective RNA molecules as a novel treatment method to overcome early embryonic developmental arrestFrom1 Oct 2021 → 14 Sep 2023Funding: FWO junior postdoctoral fellowship
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Research equipment for behavior analysis in zebrafish disease models.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- Identification of modifier genes underlying the phenotypic variability in the ‘Brittle Bone Disease’, using zebrafish models and patient-derived induced pluripotent stem cellsFrom1 Oct 2019 → TodayFunding: BOF - projects
Publications
21 - 30 of 56
- Nucleic acids enrichment of fungal pathogens to study host-pathogen interactions(2019)
Authors: Antonio José Rodriguez Sánchez, Brecht Guillemyn, Paul Coucke, Mario Vaneechoutte
- The zebrafish as a model for fragile bone disorders(2019)
Authors: Jan Willem Bek, Hanna De Saffel, Osama Essawi, Adelbert De Clercq, Paul Witten, Ann Huysseune, Juriaan Metz, Phil Salmon, Paul Coucke, Andy Willaert
Number of pages: 1 - The inflammasome pathway is involved in PXE through IL1B upregulation in patients with a severe cardiovascular PXE phenotype(2019)Volume: 27
Authors: Eva De Vilder, L. Martin, G. Leftheriotis, Paul Coucke, Anne De Paepe, Filip Van Nieuwerburgh, Olivier Vanakker
Pages: 124 - 125 - Comprehensive re-assessment of causality of ABCC6 missense variants associated with pseudoxanthoma elasticum(2019)Volume: 27
Authors: Shana Verschuere, Paul Coucke, Olivier Vanakker
Pages: 1269 - 1270 - CRISPR/Cas9-mediated homology-directed repair by ssODNs in zebrafish induces complex mutational patterns resulting from genomic integration of repair-template fragments(2018)
Authors: Annekatrien Boel, Hanna De Saffel, Wouter Steyaert, Bert Callewaert, Anne De Paepe, Paul Coucke, Andy Willaert
- BATCH-GE : analysis of NGS data for genome editing assessment(2018)Series: Methods in Molecular Biology
Authors: Wouter Steyaert, Annekatrien Boel, Paul Coucke, Andy Willaert, Kris Vleminckx
Pages: 83 - 90 - Homozygosity for CREB3L1 premature stop codon in first case of recessive osteogenesis imperfecta associated with OASIS-deficiency to survive infancy(2018)
Authors: Katarina Lindahl, Eva Astrom, Anca Dragomir, Sofie Symoens, Paul Coucke, Sune Larsson, Eleftherios Paschalis, Paul Roschger, Sonja Gamsjaeger, Klaus Klaushofer, et al.
Pages: 268 - 277 - A novel fibrillin-1 mutation in an Egyptian Marfan family : a proband showing nephrotic syndrome due to focal segmental glomerulosclerosis(2017)
Authors: Mohammad Al-Haggar, Ashraf Bakr, Yahya Wahba, Paul Coucke, Fatma El-Hussini, Mona Hafez, Riham Eid, Abdel-Rahman Eid, Amr Sarhan, Ali Shaltout, et al.
Pages: 141 - 148 - A mild form of Stickler syndrome type II caused by mosaicism of COL11A1(2017)
Authors: Kathrine F Lauritsen, Dorte L Lildballe, Paul Coucke, Rikke Monrad, Dorte A Larsen, Pernille A Gregersen
Pages: 275 - 278 - Zebrafish modeling of the β4GalT7-deficient type of Ehlers-Danlos syndrome(2017)
Authors: Sarah Delbaere, Tim Van Damme, Paul Coucke, Sofie Symoens, Delfien Syx, Andy Willaert, Fransiska Malfait
Number of pages: 1