Researcher
Paul Coucke
- Disciplines:Genetically modified animals
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Oct 2002 → 30 Sep 2018
Projects
1 - 10 of 12
- Identification of molecular mechanisms involved in Osteogenesis ImperfectaFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- Identification of modifier genes responsible for the phenotypic variability in Osteogenesis Imperfecta (OI)- patients using zebrafish modelsFrom14 Feb 2024 → TodayFunding: BOF - doctoral mandates
- Nuclear Transfer for female-related infertility and mitochondrial diseasesFrom1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Unravelling the mitochondrial DNA reversion phenomenonFrom1 Nov 2022 → TodayFunding: FWO fellowships
- Cofunding core facility - Core Zebrafish Facility Ghent (Core ZFG)From1 Jul 2022 → TodayFunding: BOF - research organisations
- Comparison of editing, complementing or replacement of defective RNA molecules as a novel treatment method to overcome early embryonic developmental arrestFrom1 Oct 2021 → 14 Sep 2023Funding: FWO junior postdoctoral fellowship
- An integrated translational platform to improve the management and outcome of rare heritable connective tissue diseaseFrom1 Jan 2021 → TodayFunding: BOF - projects
- Research equipment for behavior analysis in zebrafish disease models.From1 Dec 2020 → 30 Nov 2022Funding: BOF - scientific equipment program
- Identification of modifier genes underlying the phenotypic variability in the ‘Brittle Bone Disease’, using zebrafish models and patient-derived induced pluripotent stem cellsFrom1 Oct 2019 → TodayFunding: BOF - projects
- Genetic analysis in consanguineous families from Palestine : a focus on Cystic Fibrosis and Osteogenesis ImperfectaFrom1 Oct 2015 → 30 Sep 2019Funding: BOF - Doctoral projects
Publications
41 - 50 of 56
- Whole exome sequencing is an efficient, sensitive and specific method of mutation detection in osteogenesis imperfecta and Marfan syndrome(2013)
Authors: Aideen M Mclnerney-Leo, Mhairi S Marshall, Brooke Gardiner, Paul Coucke, Lut Van Laer, Bart L Loeys, Kim M Summers, Sofie Symoens, Jennifer A West, Malcolm J West, et al.
- A sensitive and specific diagnostic test for hearing loss using a microdroplet PCR-based approach and next generation sequencing(2013)
Authors: Isabelle Schrauwen, Manou Sommen, Jason J Corneveaux, Rebecca A Reiman, Nicole J Hackett, Charlotte Claes, Kathleen Claes, Maria Bitner-Glindzicz, Paul Coucke, Guy Van Camp, et al.
Pages: 145 - 152 - First report of the genetic background of Marfan syndrome in Polish patients(2013)
Authors: Ewa Wypasek, Daniel P Potaczek, Renata Stapor, Paul Coucke, Julie De Backer, Anne De Paepe, Anetta Undas
Pages: 646 - 648 - Arterial tortuosity syndrome : case report(2012)
Authors: C Karakurt, G Koçak, Ö Elkiran, Paul Coucke, L Van Maldergem
Pages: 477 - 482 - A new case of dendritic cell immunodeficiency: the 'DCML-like' syndrome(2012)Volume: 32
Authors: Tessa Kerre, Melissa Dullaers, Dorine Sichien, Reinhart Speeckaert, Paul Coucke, B. Lambrecht, K. Vermaelen
Pages: 88 - 89 - Short stature, severe aortic root dilation, skin hyperextensibility, extreme joint laxity and craniofacial dysmorphic features: a probable new syndrome(2010)
Authors: Elke Verstraeten, Sofie Symoens, Marjolijn Renard, Bert Callewaert, K Vandekerckhove, Julie De Backer, Fransiska Malfait, L Marks, Paul Coucke, Anne De Paepe, et al.
Pages: 119 - 122 - Cytogenetic and Array-CGH Characterization of a 6q27 Deletion in a Patient With Developmental Delay and Features of Ehlers-Danlos Syndrome(2010)
Authors: AL Mosca, P Callier, A Masurel-Paulet, C Thauvin-Robinet, N Marle, M Nouchy, F Huet, D Dipanda, Anne De Paepe, Paul Coucke, et al.
Pages: 1314 - 1317 - Anomalies leading to the mineralization of elastic fibers in pseudoxanthoma elasticum and the PXE-like syndrome(2009)Volume: 129
Authors: Y Le Corre, L Martin, Olivier Vanakker, L Schurgers, D Gheduzzi, C Vermeer, I Pasquali-Ronchetti, Paul Coucke, Anne De Paepe
Pages: P39 - P39 - A hotspot splicing mutation in LEPREI affects prolyl 3-hydroxylation and causes recessive osteogenesis imperfecta(2008)Volume: 58
Authors: Fransiska Malfait, Andy Willaert, Sofie Symoens, Paul Coucke, Anne De Paepe
Pages: S223 - S223 - A Hotspot Splicing Mutation in LEPREI Affects Prolyl 3-hydroxylation and Causes Recessive Osteogenesis Imperfecta(2008)Volume: 23
Authors: Andy Willaert, Sofie Symoens, Fransiska Malfait, Kris Gevaert, Paul Coucke, Anne De Paepe
Pages: S294 - S294