Researcher
Pieter Van Vlierberghe
- Keywords:acute lymfoblastic leukemia
- Disciplines:Cell signalling, Cancer therapy, Epigenetics, Cancer biology
Affiliations
- Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 29 Dec 2022 - Department of Pediatrics and medical genetics (Department)
Member
From1 Sep 2007 → 30 Sep 2018
Projects
21 - 30 of 59
- The role of TET2 in (pre)-leukemic T-cell acute lymphoblastic leukemiaFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- High throughput MS-based histone PTM screening: Filling a void in pharmacoepigenetics.From1 Nov 2019 → 23 Dec 2023Funding: FWO Strategic Basic Research Grant
- The role of BRWD2/PHIP as a novel epigenetic tumor suppressor in T-cell acute lymphoblastic leukemia and lymphomaFrom1 Jan 2019 → 31 Dec 2022Funding: Foundations, funds and other with scientific goal
- Novel mouse models of mantle cell lymphoma for preclinical testing of anti-leukemic drugsFrom1 Jan 2019 → 31 Dec 2019Funding: FWO research grant KAN
- Towards a broader use of a less toxit L-asparaginase variant for the treatment of human cancerFrom1 Jan 2019 → 31 Dec 2020Funding: Foundations, funds and other with scientific goal
- Preclinical evaluation of withaferin A chemosensitation in GC therapy resistant B-and T-cll heaematological malignanciesFrom1 Oct 2018 → 30 Sep 2022Funding: Foundations, funds and other with scientific goal
- Screening for drivers and dependency factors in a novel genetic model for T-ALL in Xenopus tropicalisFrom1 Oct 2018 → 31 Dec 2022Funding: FWO fellowships
- Targeted immunotherapy for the treatment of T-cell acute lymphoblastic leukemiaFrom1 Sep 2018 → 31 Aug 2019Funding: Foundations, funds and other with scientific goal
- Targeting oncogenic PIM1 kinase activation in T-cell acute lymphoblastic leukemia and lymphomaFrom1 Sep 2018 → 31 Aug 2021Funding: Foundations, funds and other with scientific goal
- Unravelling cellular heterogeneity and dynamics in normal and malignant hematopoiesis using singlecell bioinformaticsFrom1 Jan 2018 → 31 Dec 2022Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 193
- RNA helicase DHX15 exemplifies a unique dependency in acute leukemia(2023)
Authors: Hao Guo, Jin Xu, Peiqi Xing, Qilong Li, Donghai Wang, Chao Tang, Bruno Palhais, Juliette Roels, Jiaxu Liu, Sa Pan, et al.
Pages: 2029 - 2043 - In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia(2023)
Authors: Maaike Van Trimpont, Amanda M. Schalk, Yanti De Visser, Hien Anh Nguyen, Lindy Reunes, Katrien Vandemeulebroecke, Evelien Peeters, Ying Su, Hyun Lee, Philip L. Lorenzi, et al.
Pages: 409 - 419 - SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry(2023)
Authors: Bieke Decaesteker, Amber Louwagie, Fanny De Vloed, Sarah-Lee Bekaert, Suzanne Vanhauwaert, Sara De Brouwer, Ellen Sanders, A Berezovskaya, Geertrui Denecker, Stéphane Van Haver, et al.
- Mutations in the histone methyltransferase Ezh2 drive context-dependent leukemia in Xenopus tropicalis(2023)
Authors: Dieter Tulkens, Marthe Boelens, Thomas Naert, Marjolein Carron, Suzan Demuynck, Sylviane Dewaele, Gert Van Isterdael, David Creytens, Tim Pieters, Steven Goossens, et al.
Pages: 2404 - 2413 - Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF(2023)
Authors: Kai Ling Liang, Juliette Roels, Marieke Lavaert, Tom Putteman, Lena Böhme, Laurentijn Tilleman, Imke Velghe, Valentina Pegoretti, Inge Van de Walle, Stephanie Sontag, et al.
Pages: 474 - 486 - In vivo stabilization of a less toxic asparaginase variant leads to a durable anti-tumor response in acute leukemia(2023)
Authors: Amanda M. Schalk, Yanti De Visser, Hien Anh Nguyen, Lindy Reunes, Evelien Peeters, Ying Su, Hyun Lee, Philip L. Lorenzi, Wai-Kin Chan, Veerle Mondelaers, et al.
Pages: 409 - 419 - Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of T-cell lymphoblastic lymphoma(2023)
Authors: Tom Putteman, Mattias Landfors, Lindy Reunes, Wouter Van Loocke, Morgan Thenoz, Natalia Mackowska-Maslak, Tom Taghon, Marc R. Mansour, Nadine Farah, Koen Norga, et al.
- TXNIP promotes human NK cell development but is dispensable for NK cell functionality(2022)
Authors: Sigrid Wahlen, Sylvie Taveirne, Wouter Van Loocke, Els Van Ammel, Filip Van Nieuwerburgh, Tom Taghon, Pieter Van Vlierberghe, Georges Leclercq
- Functional mapping of PHF6 complexes in chromatin remodeling, replication dynamics and DNA repair(2022)
Authors: Silvia Alvarez, Ana da Silva Almeida, Robert Albero, Mayukh Biswas, Angelica Barreto-Galvez, Thomas S. Gunning, Anam Shaikh, Tomas Aparicio, Agnieszka Anya Wendorff, Erich Piovan, et al.
Pages: 3418 - 3429 - Direct and indirect anti-leukemic properties of Activity-on-Target interferons for the treatment of T-cell acute lymphoblastic leukemia(2022)
Authors: Renate De Smedt, Willem Daneels, Pieter Van Vlierberghe, Jan Tavernier
Pages: 1448 - 1453
Patents
1 - 1 of 1