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Researcher
Raf Sciot
- Disciplines:Macromolecular and materials chemistry, Laboratory medicine, Morphological sciences
Affiliations
- Translational Cell & Tissue Research (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 9 of 9
- Optical genome mapping for comprehensive genetic analysis of sarcomas in a diagnostic setting.From1 Jan 2023 → TodayFunding: FWO Humanitarian research project Stand up against Cancer
- Whole-genome optical mapping for comprehensive analysis of sarcoma genomes in a diagnostic settingFrom13 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Direct detection and identification of neuro-oncology markers in brain tumoursFrom1 Oct 2019 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Determination of genetic and therapeutic dependencies of patient-derived models of brain cancerFrom1 Oct 2017 → 30 Sep 2021Funding: Fund Recuperation Fiscal Exemption
- Establishment of new research models and in vivo efficacy testing of novel treatment strategies for resistant gastrointestinal stromal tumorsFrom1 Aug 2014 → 19 May 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Human soft tissue sarcomas xenograft mouse models as an opportunity to improve the therapeutic options for patients.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
- Identification of novel protein kinase targets for the improvement of gastrointestinal stromal tumor (GIST) therapy: a paradigm for the optimisation of kinase targeted therapies.From1 Jan 2011 → 31 Dec 2016Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- Neuropathological and functional characterization of the therapeutic effect of parkin in animal models of Parkinson's disease.From25 Aug 2009 → 7 Feb 2014Funding: FWO fellowships
Publications
11 - 20 of 260
- Inflammatory Myofibroblastic Tumor of the Abdomen: Clinicopathological and Molecular Characterization of Seventeen Cases, Including Three Epithelioid Inflammatory Myofibroblastic Sarcomas, Highlighting Potential Therapeutic Targets(2023)
Authors: Raf Sciot
Pages: S74 - S76 - MS1-Based Data Analysis Approaches for FFPE Tissue Imaging of Endogenous Peptide Ions by Mass Spectrometry Histochemistry (MSHC).(2023)
Authors: Raf Sciot
Pages: 187 - 202 - HistoSnap: A Novel Software Tool to Extract m/z-Specific Images from Large MSHC Datasets.(2023)
Authors: Raf Sciot
Pages: 15 - 26 - Molecular characterization of an embryonal rhabdomyosarcoma occurring in a patient with Kabuki syndrome: report and literature review in the light of tumor predisposition syndromes(2023)
Authors: Raf Sciot
Pages: 103 - 118 - Melanoma cell plasticity poses diagnostic challenges: a case series(2022)
Authors: Yannick Van Herck, Raf Sciot, Isabelle Vanden Bempt, Veerle Boecxstaens, Maria Garmyn, Oliver Bechter
Pages: 428 - 439 - Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour(2022)
Authors: Patrick Schöffski, Raf Sciot
Pages: 1793 - 1798 - A MULTI-OMIC, FUNCTIONAL PRECISION ONCOLOGY METHOD TO IDENTIFY RESPONSIVE GLIOBLASTOMA TUMOR CELLS AT SINGLE CELL RESOLUTION(2022)
Authors: Yanti De Visser, Dena Panovska, Steven De Vleeschouwer, Lien Solie, Paul Clement, Raf Sciot, Frederik De Smet
Pages: 7 - 7 - Generation of patient-derived models from a metastatic pediatric diffuse leptomeningeal glioneuronal tumor with KIAA1549::BRAF fusion(2022)
Authors: Julie Messiaen, Lien Spans, Anne Uyttebroeck, Bart Depreitere, Isabelle Vanden Bempt, Raf Sciot, Frederik De Smet
Pages: 793 - 797 - GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide(2022)
Authors: Steven De Vleeschouwer, Raf Sciot, Jenny Weng, Francesca Bosisio, Gabriele Bergers, Frederik De Smet, Diether Lambrechts, Sarah-Maria Fendt
- Plocabulin, a Novel Tubulin Inhibitor, Has Potent Antitumour Activity in Patient-Derived Xenograft Models of Soft Tissue Sarcoma(2022)
Authors: Agnieszka Wozniak, Maria Debiec-Rychter, Raf Sciot, Patrick Schöffski