Researcher
Rita Derua
- Disciplines:Posttranslational modifications, Interactomics, Proteomics, Spectrometry
Affiliations
- Laboratory of Protein Phosphorylation and Proteomics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 11
- Ultra-sensitive minimal residual disease assessment by blood-based clonotypic mass spectrometry approach in plasma cell dyscrasias (MASSIAS)From1 Oct 2023 → TodayFunding: FWO Applied Biomedical Research (TBM)
- Targeted mass spectrometry-based quantification of autoantibodies in systemic rheumatic diseasesFrom1 Oct 2021 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Development and clinical validation of a multiplexed massspectrometry- based assay to improve diagnosis of Rheumatoid ArthritisFrom1 Jan 2021 → 31 Dec 2022Funding: FWO Applied Biomedical Research (TBM)
- Mass spectrometry-based autoantibody tests for specific diagnosis of autoimmune diseasesFrom1 Oct 2020 → 30 Sep 2022Funding: IOF - technology validation in lab
- Translational research related to Corona-Covid 19From1 Apr 2020 → 31 Mar 2021Funding: IOF - technology validation in lab, BOF - various
- Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatmentFrom1 Jan 2019 → 15 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting radiotherapy resistance in Head and Neck Cancers: the potential biomarker role of TIPRL1 and CIP2A, two cellular inhibitors of Protein Phosphatase 2AFrom1 Jan 2018 → 22 Nov 2023Funding: BOF - doctoral mandates
- Targeting radiation resistance of Head and Neck Squamous Cell CarcinomaFrom1 Oct 2017 → 30 Sep 2021Funding: Fund Recuperation Fiscal Exemption, BOF - Concerted Research Project from 1994
- The role of the Protein Phosphatase 2A Activator PTPA in KRAS-mutant non-small-cell lung cancer development and treatment resistanceFrom1 Feb 2015 → 10 Nov 2021Funding: BOF - Doctoral projects
- Novel insights in the pharmacological inhibition and isoform-specific regulation of protein kinase D2.From1 Mar 2013 → 5 Jul 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 93
- CD4+ T cells from individuals with type 1 diabetes respond to a novel class of deamidated peptides formed in pancreatic islets.(2024)
Authors: Rita Derua, Chantal Mathieu, Lut Overbergh
Pages: db230588 - Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatment(2023)
Authors: Liesbeth Guffens, Veerle Janssens, Rita Derua
- Targeting radiotherapy resistance in Head and Neck Cancers: the potential biomarker role of TIPRL1 and CIP2A, two cellular inhibitors of Protein Phosphatase 2A(2023)
Authors: Célie Cokelaere, Veerle Janssens, Rita Derua, Sandra Nuyts
- PME-1-regulated neural cell death: new therapeutic opportunities?(2023)
Authors: Liesbeth Guffens, Rita Derua, Veerle Janssens
Pages: 11694 - 11696 - Autoantibodies against the NineTeen complex and U5 RNP in systemic sclerosis(2023)
Authors: Rita Derua, Wim Wuyts, Daniel Engelbert Blockmans, Petra De Haes, Ellen De Langhe, Xavier Bossuyt
- PME-1 sensitizes glioblastoma cells to oxidative stress-induced cell death by attenuating PP2A-B55α-mediated inactivation of MAPKAPK2-RIPK1 signaling(2023)
Authors: Liesbeth Guffens, Rita Derua, Veerle Janssens
- Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality.(2023)
Authors: Jos van Pelt, Rita Derua, Liesbeth Guffens, Veerle Janssens, Chris Verslype
- NET Proteome in Established Type 1 Diabetes Is Enriched in Metabolic Proteins(2023)
Authors: Samal Bissenova, Rita Derua, Chantal Mathieu, Conny Gysemans, Lut Overbergh
- Identification of Peroxisome-Derived Hydrogen Peroxide-Sensitive Target Proteins by a YAP1C-based genetic probe(2023)
Authors: Celien Lismont, Cláudio Figueiredo Costa, Paul P Van Veldhoven, Rita Derua, Marc Fransen
Pages: 161 - 181 - Mass spectrometry-based identification of new anti-Ly and known antisynthetase autoantibodies(2023)
Authors: Jean-Baptiste Vulsteke, Rita Derua, Petra De Haes, Daniel Engelbert Blockmans, Wim Wuyts, Kristl Claeys, Ellen De Langhe, Xavier Bossuyt
Pages: 546 - 555