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Researcher
Romain Lefebvre
- Keywords:gastrointestinal neuropharmacology
- Disciplines:Clinical trials, Gastro-enterology, In vitro testing, Pharmacodynamics, Small molecules, Pharmacokinetics
Affiliations
- Department of Basic and Applied Medical Sciences (Department)
Member
From1 Oct 2018 → Today - Department of Pharmacology (Department)
Responsible
From1 May 2006 → 30 Sep 2018 - Department of Pharmacology (Department)
Member
From1 May 2006 → 30 Sep 2018 - Department of Pharmacology (Department)
Member
From1 Jan 1993 → 30 Sep 2018
Projects
1 - 2 of 2
- Modulation of the cGMP pathway by oxidative stress in smooth muscle relaxation and inflammationFrom1 Jan 2010 → 31 Oct 2017Funding: BOF - Concerted Research Project from 1994
- Modulation of the cGMP pathway by oxidative stress in smooth muscle relaxation and inflammationFrom1 Jan 2010 → 31 Oct 2017Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 50
- Hemin reduces postoperative ileus in a heme oxygenase 1‐dependent manner while dimethyl fumarate does without heme oxygenase 1‐induction(2020)
Authors: Jonas Van Dingenen, Leen Pieters, Elien Van Nuffel, Romain Lefebvre
- The H2S-releasing naproxen derivative ATB-346 and the slow-release H2S donor GYY4137 reduce intestinal inflammation and restore transit in postoperative ileus(2019)
Authors: Jonas Van Dingenen, Leen Pieters, Anne Vral, Romain Lefebvre
- cAMP catalyzing phosphodiesterases control cholinergic muscular activity but their inhibition does not enhance 5-HT4 receptor-mediated facilitation of cholinergic contractions in the murine gastrointestinal tract(2018)
Authors: Vicky Pauwelyn, Romain Lefebvre
- Influence of the slow- release H2S donor GYY4137 and the H2S- releasing naproxen derivative ATB-346 on postoperative ileus(2018)Volume: 30
Authors: Jonas Van Dingenen, Romain Lefebvre
Pages: 23 - 23 - Dimethyl fumarate vs hemin for the induction of heme oxygenase-1 as treatment strategy for murine postoperative ileus(2018)Volume: 30
Authors: Jonas Van Dingenen, Romain Lefebvre
Pages: 176 - 176 - 5-HT4 receptors facilitate cholinergic neurotransmission throughout the murine gastrointestinal tract(2017)
Authors: Vicky Pauwelyn, Romain Lefebvre
- Influence of phosphodiesterases on basal and 5-HT4 receptor-facilitated cholinergic contractility in the murine gastrointestinal tract(2017)Volume: 80
Authors: Vicky Pauwelyn, Els Van Deynse, Romain Lefebvre
Number of pages: 1 - Protective effect of exogenous nitrite in postoperative ileus(2015)
Authors: Sarah Cosyns, S Shiva, Romain Lefebvre
Pages: 4864 - 4874 - Facilitation of murine enteric cholinergic neurotransmission by 5-HT4 receptor activation : control by phosphodiesterases(2015)Volume: 27
Authors: Vicky Pauwelyn, Els Van Deynse, Romain Lefebvre
Pages: 91 - 91 - Control of the signalling pathway of 5-HT4 receptors in cholinergic neurons of human colon by phosphodiesterases(2015)Volume: 13
Authors: Vicky Pauwelyn, Inge Van Colen, Wim Ceelen, Romain Lefebvre
Number of pages: 1