Researcher
Roosmarijn Vandenbroucke
- Keywords (Ghent University):extracellular vesicles, gut inflammation, blood-brain barrier, neuroinflammation, aging, brain targeting
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Adaptive immunology, Bacteriology
- Disciplines (Ghent University):Cell signalling, Inflammation, Innate immunity, Membrane structure and transport, Gastro-enterology, Infectious diseases, Neurosciences not elsewhere classified, Microbiome
Affiliations
- Board of Governors/Executive Board (Administrative office)
Member
From1 Oct 2022 → Today - Vandenbroucke Lab (Research group)
Responsible
From1 Mar 2018 → Today - Libert Lab (Research group)
Member
From1 Jan 2017 → 28 Feb 2018 - Department of Pharmaceutics (Department)
Member
From1 Jan 2003 → 30 Sep 2008 - Department of Biomedical molecular biology (Department)
Member
From1 Oct 2001 → Today
Projects
1 - 10 of 24
- The impact of a SARS-CoV-2 infection on brain pathology and vice versa.From1 Nov 2023 → TodayFunding: FWO fellowships
- The foes and friends among the adaptive immune system in Alzheimer’s diseaseFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- OTULIN in neuroinflammation, multiple sclerosis and Alzheimer pathologyFrom1 Jan 2023 → TodayFunding: BOF - doctoral mandates
- Investigating the biomarker potential and pathological role of extracellular vesicles in Parkinson’s disease.From1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Fine tuning and engaging the immune system to defeat Alzheimer’s disease.From1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Investigating the biomarker potential and pathological role of neuronal- and bacterial- derived extracellular vesicles in Parkinson’s disease.From1 Oct 2021 → 30 Sep 2022Funding: BOF - postdoctoral mandates
- High-precision Sulfur & Selenium isotopic analysis: a novel approach for studying brain redox imbalance & diagnosing/prognosing neurological disorders?From1 Oct 2021 → TodayFunding: BOF - projects
- Extracellular vesicle (EV) transport across the brain barriers: from mechanistic and biological insights towards strategies for delivery of therapeutics to the brain.From1 Jan 2021 → TodayFunding: BOF - projects
- Unraveling the heterogeneity of the choroid plexus tissue and its cell (sub)type-specific response to different inflammatory triggers.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
Publications
21 - 30 of 34
- Choroid plexus-derived miR-204 regulates the number of quiescent neural stem cells in the adult brain(2019)
Authors: Tjasa Lepko, Melanie Pusch, Tamara Mueller, Dorothea Schulte, Janina Ehses, Michael Kiebler, Julia Hasler, Hagen B. Huttner, Roosmarijn Vandenbroucke, Charysse Vandendriessche, et al.
- Interferons : a molecular switch between damage and repair in ageing and Alzheimer's disease(2019)
Authors: Nina Gorlé, Roosmarijn Vandenbroucke
- Immunogenicity and protection efficacy of a naked self-replicating mRNA-based Zika virus vaccine(2019)
Authors: Zifu Zhong, João Paulo Portela Catani, Séan Mc Cafferty, Liesbeth Couck, Wim Van Den Broeck, Nina Gorlé, Roosmarijn Vandenbroucke, Bert Devriendt, Sebastian Ulbert, Lieselotte Cnops, et al.
- A study of cecal ligation and puncture-induced sepsis in tissue-specific tumor necrosis factor receptor 1-deficient mice(2019)
Authors: Jolien Vandewalle, Sophie Steeland, Sara Van Ryckeghem, Melanie Eggermont, Elien Van Wonterghem, Roosmarijn Vandenbroucke, Claude Libert
- Biological membranes in EV biogenesis, stability, uptake, and cargo transfer : an ISEV position paper arising from the ISEV membranes and EVs workshop(2019)
Authors: Ashley E Russell, Alexandra Sneider, Kenneth W Witwer, Paolo Bergese, Suvendra N Bhattacharyya, Alexander Cocks, Emanuele Cocucci, Uta Erdbrugger, Juan M Falcon-Perez, David W Freeman, et al.
- Overexpression of Gilz protects mice against lethal septic peritonitis(2019)
Authors: Marlies Ballegeer, Jolien Vandewalle, Melanie Eggermont, Gert Van Isterdael, Lien Dejager, Liesbet De Bus, Johan Decruyenaere, Roosmarijn Vandenbroucke, Claude Libert
Pages: 208 - 214 - Simultaneous inhibition of tumor necrosis factor receptor 1 and matrix metalloproteinase 8 completely protects against acute inflammation and sepsis(2018)
Authors: Sophie Steeland, Sara Van Ryckeghem, Jolien Vandewalle, Marlies Ballegeer, Elien Van Wonterghem, Melanie Eggermont, Johan Decruyenaere, Liesbet De Bus, Claude Libert, Roosmarijn Vandenbroucke
Pages: e67 - e75 - Mouse models of ageing and their relevance to disease(2016)
Authors: Sulev Kõks, Soner Dogan, Bilge Guvenc Tuna, Herminia González-Navarro, Paul Potter, Roosmarijn Vandenbroucke
Pages: 41 - 53 - A hidden epithelial barrier in the brain with a central role in regulating brain homeostasis implications for aging(2016)
Authors: Roosmarijn Vandenbroucke
Pages: S407 - S410 - Endothelial LRP1 transports amyloid-β1-42 across the blood-brain barrier(2016)
Authors: Steffen E Storck, Sabrina Meister, Julius Nahrath, Julius N Meissner, Nils Schubert, Alessandro Di Spiezio, Sandra Baches, Roosmarijn Vandenbroucke, Yvonne Bouter, Ingrid Prikulis, et al.
Pages: 123 - 136