Researcher
Ruben Boon
- Disciplines:Genetics, Systems biology, Molecular and cell biology, Morphological sciences, Oncology
Affiliations
- Laboratory for Functional Epigenetics (Division)
Member
From1 Sep 2021 → 31 Jan 2022 - Stem Cell and Developmental Biology (Division)
Member
From1 Apr 2013 → 31 Aug 2021
Projects
1 - 1 of 1
- Metabolomics of stem cell differentiation.From13 Aug 2012 → 13 Dec 2017Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 34
- A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes(2022)
Authors: Manoj Gautam, Tine Tricot, Ruben Boon, Burak Toprakhisar, Catherine Verfaillie
Pages: 702 - 712Number of pages: 11 - Metabolic Fuel for Epigenetic: Nuclear Production Meets Local Consumption(2021)
Authors: Ruben Boon
Number of pages: 15 - A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model(2021)
Authors: Manoj Gautam, Burak Toprakhisar, Ruben Boon, Tine Tricot, Jolan De Boeck, Adrian Ranga, Francesca Maria Bosisio, Tania Roskams, Catherine Verfaillie
Number of pages: 18 - HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations(2021)
Authors: Raheem Fazal, Mathias De Decker, Laura Fumagalli, Joni Vanneste, Wenting Guo, Ruben Boon, Thomas Vercruysse, Bart Swinnen, Pieter Vanden Berghe, Catherine Verfaillie, et al.
Number of pages: 24 - Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes(2021)
Authors: Ruben Boon, Catherine Verfaillie
Number of pages: 12 - A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma(2021)
Authors: Ruben Boon
Pages: 182 - +Number of pages: 25 - PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells(2021)
Authors: Jonathan De Smedt, Irene Talón, Sreya Hillol Ghosh, Burak Toprakhisar, Rodrigo Furtado Madeiro Da Costa, Samantha Zaunz, Ruben Boon, Catherine Verfaillie
Number of pages: 18 - Nuclear metabolism and the regulation of the epigenome(2020)
Authors: Ruben Boon
Pages: 1190 - 1203Number of pages: 14 - Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines(2020)
Authors: Ruben Boon, Manoj Gautam, Tine Tricot, Ilaria Elia, Jonathan De Smedt, Guy Eelen, Matthew Bird, Philip Roelandt, Ginevra Doglioni, Matteo Rossi, et al.
Number of pages: 16 - Breast cancer cells rely on environmental pyruvate to shape the metastatic niche(2019)
Authors: Ilaria Elia, Matteo Rossi, Steve Stegen, Dorien Broekaert, Ginevra Doglioni, Ruben Boon, Catherine Verfaillie, Eric Verbeken, Gertrudis Carmeliet, Sarah-Maria Fendt
Pages: 117 - +Number of pages: 23