Researcher
Sandra Van Lint
- Keywords:Dendritic cells, Cancer Immunotherapy, mRNA, tumor microenvironment, Adaptive immune system, T-cells
- Disciplines:Immunology not elsewhere classified, Vaccinology, Cancer therapy, Transcription and translation, Cell signalling, Adaptive immunology, Applied immunology, Cancer biology, Immunogenetics, Innate immunity, Cancer prevention
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Jan 2021 → Today - Department of Biomolecular Medicine (Department)
Member
From1 Oct 2018 → 31 Dec 2020 - Department of Biochemistry (Department)
Member
From1 Feb 2015 → 30 Sep 2018
Projects
1 - 2 of 2
- REACTION: A modular mRNA-encoded artificial receptor for focused re-ignition of anti-cancer immune responsesFrom1 Oct 2023 → TodayFunding: BOF - projects
- ACT: AcTakine-based Cancer TherapyFrom1 Oct 2015 → 30 Sep 2018Funding: BOF - Other initiatives
Publications
1 - 10 of 17
- A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state(2023)
Authors: Sandra Van Lint, Alexander Van Parys, Bram Van Den Eeckhout, Niels Vandamme, Stephane Plaisance, Annick Verhee, Dominiek Catteeuw, Elke Rogge, Jennifer De Geest, Nele Vanderroost, et al.
- mRNA in cancer immunotherapy : beyond a source of antigen(2021)
Authors: Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Ine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
- Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice(2019)
Authors: Anje Cauwels, Sandra Van Lint, Dominiek Catteeuw, Shengru Pang, Franciane Paul, Elke Rogge, Annick Verhee, Marco Prinz, Niko Kley, Gilles Uzé, et al.
Pages: 70 - 76 - Targeting the tumor microenvironment to enhance antitumor immune responses(2015)
Authors: Kevin Van Der Jeught, Lukasz Bialkowski, Lidia Daszkiewicz, Katrijn Broos, Cleo Goyvaerts, Dries Renmans, Sandra Van Lint, Carlo Heirman, Kris Thielemans, Karine Breckpot
Pages: 1359 - 1381 - Immunogenicity of targeted lentivectors(2014)
Authors: Cleo Goyvaerts, Kurt De Groeve, Sandra Van Lint, Carlo Heirman, Jo A Vanginderachter, Patrick De Baetselier, Geert Raes, Kris Thielemans, Karine Breckpot
Pages: 704 - 715 - Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula(2014)
Authors: Sandra Van Lint, Sofie Wilgenhof, Carlo Heirman, Jurgen Corthals, Karine Breckpot, Aude Bonehill, Bart Neyns, Kris Thielemans
Pages: 959 - 967 - Development of a local treatment modality for the systemic cure of cancer using mRNA as a medicinal product(2014)
Authors: Sandra Van Lint
- Enhanced suppressive capacity of tumor-infiltrating myeloid-derived suppressor cells compared with their peripheral counterparts(2014)
Authors: Sarah K Maenhout, Sandra Van Lint, Perpetua U Emegi, Kris Thielemans, Joeri L Aerts
Pages: 1077 - 1090 - Priming of cytotoxic T lymphocyte responses by dendritic cells: induction of potent anti-tumor immune responses(2013)
Authors: Sandra Van Lint, An MT van Nuffel, Sofie Wilgenhof, Daphné Benteyn, Joeri Pen, David Escors, Aude Bonehill, Bart Neyns, Kris Thielemans, Karine Breckpot, et al.
Pages: 1 - 32 - mRNA: from a chemical blueprint for protein production to an off-the-shelf therapeutic(2013)
Authors: Sandra Van Lint, Carlo Heirman, Kris Thielemans, Karine Breckpot
Pages: 265 - 274
Patents
1 - 1 of 1
- BISPECIFIC SIGNALING AGENT AND USES THEREOF (Inventor)