Researcher
Sarah El Kharraz
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Biochemistry and metabolism, Medical systems biology, Molecular and cell biology, Oncology
- See also: Sarah El Kharraz (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Member
From8 Aug 2022 → Today - Fendt Lab (Research group)
Member
From8 Aug 2022 → 31 Dec 2023 - Laboratory of Molecular Endocrinology (Division)
Member
From1 Sep 2017 → 7 Aug 2022
Projects
1 - 1 of 1
- What is the role of recepter dimerization in androgen action?From5 Sep 2017 → 19 May 2022Funding: FWO fellowships
Publications
1 - 8 of 8
- Testosterone Restores Body Composition, Bone Mass, and Bone Strength Following Early Puberty Suppression in a Mouse Model Mimicking the Clinical Strategy in Trans Boys(2023)
Authors: Stefanie Doms, Sarah El Kharraz, Vera Maria Johanna Sommers, Karel David, Christa Maes, Leen Antonio, Brigitte Decallonne, Geert Carmeliet, Frank Claessens, Dirk Vanderschueren
Pages: 1497 - 1508 - A disease-associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer(2022)
Authors: Elien Smeets, Xiao Yin Lee, Christine Helsen, Sarah El Kharraz, Roy Eerlings, Stephanie Humblet-Baron, Arnout Voet, Anne Rochtus, Ann Van Schepdael, Francis de Zegher, et al.
Pages: 2242 - 2253 - N/C interactions are dispensable for normal in vivo functioning of the androgen receptor in male mice(2022)
Authors: Sarah El Kharraz, Vanessa Dubois, Elien Smeets, Roy Eerlings, Dirk Vanderschueren, Christine Helsen, Frank Claessens
- The role of receptor dimerization in androgen action: uncovering its physiological relevance using knockin mouse models(2022)
Authors: Sarah El Kharraz, Frank Claessens, Christine Helsen
- Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer(2022)
Authors: Lisa Moris, Bram Boeckx, Diether Lambrechts, Christine Helsen, Stefaan Soenen, Elien Smeets, Roy Eerlings, Sarah El Kharraz, Hendrik Van Poppel, Steven Joniau, et al.
Pages: 527 - 541 - Small-molecule profiling for steroid receptor activity using a universal steroid receptor reporter assay(2022)
Authors: Roy Eerlings, Tien Nguyen, Elien Smeets, Lisa Moris, Sarah El Kharraz, Arnout Voet, Wim Dehaen, Frank Claessens, Christine Helsen
- The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation.(2021)
Authors: Sarah El Kharraz, Vanessa Dubois, Tien Nguyen, Arnout Voet, Roy Eerlings, Stefan Prekovic, Elien Smeets, Lisa Moris, Kevin Verstrepen, Geert Carmeliet, et al.
Pages: 1 - 19 - Drivers of AR indifferent anti-androgen resistance in prostate cancer cells(2019)
Authors: Florian Handle, Stefan Prekovic, Christine Helsen, Thomas Van den Broeck, Elien Smeets, Lisa Moris, Roy Eerlings, Sarah El Kharraz, Steven Joniau, Frank Claessens