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Researcher
Sarah-Maria Fendt
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Biochemistry and metabolism, Medical systems biology, Molecular and cell biology, Oncology
- See also: Fendt SM (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Responsible
From1 Oct 2013 → Today - Fendt Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Member
From1 Jan 2013 → Today
Projects
21 - 30 of 40
- Tackling cancer metastasis as a metabolic disease.From1 Jan 2020 → 31 Dec 2020Funding: Private funding of national origin - undefined
- Loss of phosphoglycerate dehydrogenase (PHGDH) promotes metastatization in triple-negative breast cancerFrom1 Oct 2019 → 30 Sep 2023Funding: Foundations, funds and other with scientific goal
- In vivo CRISPR Screen of SLC Transporters Defines Microenvironment-specific Metabolic Dependencies of MetastasisFrom1 May 2019 → 26 May 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Metabolic regulation of metastatic growthFrom1 Jun 2018 → 31 May 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Exploiting metabolic regulation of extracellular matrix (ECM) formation to inhibit metastatic growthFrom8 Jan 2018 → 31 Oct 2023Funding: FWO fellowships, Foundations, funds and other with scientific goal
- Metabolic Competition between cancer and immune cellsFrom1 Jan 2018 → 31 Dec 2018Funding: FWO research grant KAN
- Phosphoglycerate dehydrogenase (PHGDH) regulates EMT and proliferation via ZEB1 and mTORC1From1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Investigating the role of fatty acid desaturation in cancerFrom20 Nov 2017 → 15 Dec 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Modeling the Metabolic Competition between Immune and Cancer Cells in the Tumor MicroenvironmentFrom1 Oct 2017 → 30 Sep 2020Funding: FWO fellowships
- The effect of rewiring fatty acid metabolism on the epigenetic landscape of metastasizing breast cancer cells.From13 Jan 2017 → 8 Jan 2019Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 126
- Serum methylmalonic acid concentrations at breast cancer diagnosis significantly correlate with clinical frailty(2024)
Authors: Sigrid Hatse, Cindy Kenis, Anke Vandekeere, Yentl Lambrechts, François Richard, Patrick Neven, Ines Nevelsteen, Christine Desmedt, Sarah-Maria Fendt, Hans Wildiers
- Metabolic heterogeneity in cancer(2024)
Authors: Xiaozheng Liu, Sarah-Maria Fendt
Pages: 18 - 38 - Spatial metabolomics principles and application to cancer research(2023)
Authors: Sebastian Igelmann, Sarah-Maria Fendt
- Challenges and opportunities in targeting metabolism(2023)
Authors: Sarah-Maria Fendt
Pages: 999 - 1001 - Loss of attachment promotes proline accumulation and excretion in cancer cells(2023)
Authors: Anke Vandekeere, Sarah-Maria Fendt
- Author Correction: CD40 signal rewires fatty acid and glutamine metabolism for stimulating macrophage anti-tumorigenic functions (vol 24, 452, 2023)(2023)
Authors: Sarah-Maria Fendt
- EXPLORING AGEING-RELATED BIOMARKERS IN INDIVIDUALS WITH BREAST CANCER AND WITHOUT CANCER(2023)
Authors: Qi Wu, Hans Wildiers, Sarah-Maria Fendt, Sigrid Hatse
- Combining the antianginal drug perhexiline with chemotherapy induces complete pancreatic cancer regression in vivo(2023)
Authors: Sarah-Maria Fendt
- In vivo CRISPR Screen of SLC Transporters Defines Microenvironment-specific Metabolic Dependencies of Metastasis(2023)
Authors: Alex Cuadros, Sarah-Maria Fendt
- Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy(2023)
Authors: Ali Talebi, Vincent de Laat, Xander Spotbeen, Jonas Dehairs, Ginevra Doglioni, David Nittner, Tania Roskams, Patrizia Agostinis, Oliver Bechter, Veerle Boecxstaens, et al.