Researcher
Serge Van Calenbergh
- Keywords:medicinal chemistry, nucleoside analogues, drug discovery, infectious diseases, glycosphingolipids
- Disciplines:Organic chemical synthesis, Bio-organic chemistry, Characterisation of biologically active (macro)molecules, Medicinal and biomolecular chemistry not elsewhere classified, Biomolecular modelling and design, Medicinal chemistry, Drug discovery and development not elsewhere classified
Affiliations
- Faculty Education Services Pharmaceutical Sciences (Administrative office)
Responsible
From1 Oct 2014 → 30 Sep 2022 - Faculty Education Services Pharmaceutical Sciences (Administrative office)
Member
From1 Oct 2014 → 30 Sep 2022 - Dean's Office of the Faculty of Pharmaceutical Sciences (Administrative office)
Member
From1 Sep 1997 → 31 Dec 1997 - Department of Pharmaceutics (Department)
Member
From1 Jan 1993 → Today
Projects
1 - 10 of 15
- Design and synthesis of inhibitors of the MEP pathwayFrom1 Jan 2024 → TodayFunding: BOF - doctoral mandates
- Uncaging the potential of photopharmacology for the treatment of epilepsyFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Evaluation of a new treatment against "blackhead" disease in turkeys (POULTRY 2)From16 Oct 2023 → TodayFunding: IOF - technology validation in lab
- Cofunding core facility - NMR Expertise CentreFrom1 Oct 2023 → TodayFunding: BOF - research organisations
- Identification of optimized Aurora Kinase A PROTACs with suitable PK properties for in vivo proof-of-concept studies (OPTIMAPK).From15 Jul 2023 → TodayFunding: IOF - technology concept exploration
- Targeting transcription factor addiction in acute leukemia (TaTFAL)From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Targeting the degradation of proteins involved in neuroblastoma with bivalent ligands.From1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Novel treatment for blackhead disease in turkeysFrom3 Aug 2020 → 30 Jun 2022Funding: IOF - technology concept exploration
- Exploiting the methylerythritol phosphate pathway as a source of drug targets for novel anti-infectivesFrom1 Apr 2020 → TodayFunding: H2020-EU.1.3.- EXCELLEN SCIENCE - Marie Skłodowska-Curie actions
- Identification of adaptive mechanisms leading to reduced antibiotic susceptibility in bacterial biofilms using experimental evolution and machine learning approachesFrom1 Jan 2020 → TodayFunding: BOF - projects
Publications
1 - 10 of 38
- Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine(2023)
Authors: Thomas Ertveldt, Sofie Meulewaeter, Yannick De Vlaeminck, Oscar Olarte, Katrijn Broos, Serge Van Calenbergh, Stephanie Bourgeois, Joke Deprez, Yves Heremans, Cleo Goyvaerts, et al.
Pages: 5483 - 5500 - Acyloxymethyl and alkoxycarbonyloxymethyl prodrugs of a fosmidomycin surrogate as antimalarial and antibacterial agents(2023)
Authors: Charlotte Courtens, Frits van Charante, Thibaut Quennesson, Martijn Risseeuw, Paul Cos, Guy Caljon, Tom Coenye, Serge Van Calenbergh
- Dual N6/C7-substituted 7-deazapurine and tricyclic ribonucleosides with affinity for G protein-coupled receptors(2023)
Authors: Simon Krols, Federica Matteucci, Kristof Van Hecke, Guy Caljon, Kenneth A. Jacobson, Serge Van Calenbergh
Pages: 81 - 86 - 3D-printed wound dressings containing a fosmidomycin-derivative prevent Acinetobacter baumannii biofilm formation(2023)
Authors: Frits van Charante, David Martínez-Pérez, Clara Guarch-Pérez, Charlotte Courtens, Andrea Sass, Emilia Choińska, Joanna Idaszek, Serge Van Calenbergh, Martijn Riool, Sebastian A. J. Zaat, et al.
- Study of G protein-coupled receptors dimerization : from bivalent ligands to drug-like small molecules(2023)
Authors: Mingcheng Qian, Zhengyang Sun, Xin Chen, Serge Van Calenbergh
- Phenethyl-4-ANPP : a marginally active byproduct suggesting a switch in illicit fentanyl synthesis routes(2022)
Authors: Marthe Vandeputte, Alex J. Krotulski, Fabian Hulpia, Serge Van Calenbergh, Christophe Stove
Pages: 350 - 357 - Optical control of excitatory transmission in hippocampal slices with photoactive adenosine A1 receptor agonist(2021)
Authors: Erine Craey, Fabian Hulpia, Serge Van Calenbergh, Lars Emil Larsen, Charlotte Mathys, Inge Van Colen, Jean Delbeke, Kristl Vonck, Paul Boon, Wytse Wadman, et al.
Number of pages: 1 - Sustainability in drug discovery(2021)
Authors: Evelien Wynendaele, Christophe Furman, Bartosz Wielgomas, Per Larsson, Eelko Hak, Thomas Block, Serge Van Calenbergh, Nicolas Willand, Michal Markuszewski, Luke R. Odell, et al.
- Report on a novel emerging class of highly potent benzimidazole NPS opioids : chemical and in vitro functional characterization of isotonitazene(2020)
Authors: Peter Blanckaert, Annelies Cannaert, Katleen Van Uytfanghe, Fabian Hulpia, Eric Deconinck, Serge Van Calenbergh, Christophe Stove
Pages: 422 - 430 - Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents(2020)
Authors: Yanlin Jian, Fabian Hulpia, Martijn Risseeuw, He Eun Forbes, Hélène Munier-Lehmann, Guy Caljon, Helena I. M. Boshoff, Serge Van Calenbergh
Patents
1 - 10 of 10
- Nucleoside analogues for the treatment of parasitic infections (Inventor)
- Sphingamide Compounds and Methods for Binding iNKT Cells (Inventor)
- Nucleoside analogues for the treatment of parasitic infections (Inventor)
- Sphingamide Compounds and Methods for Binding iNKT Cells (Inventor)
- GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS (Inventor)
- Nucleoside analogues for the treatment of parasitic infections (Inventor)
- HAMAMELITANNIN ANALOGUES AND USES THEREOF (Inventor)
- HAMAMELITANNIN ANALOGUES AND USES THEREOF (Inventor)
- NOVEL HAMAMELITANNIN ANALOGUES AND USES THEREOF (Inventor)
- GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS (Inventor)