Researcher
Steve Stegen
- Disciplines:Endocrinology and metabolic diseases
Affiliations
- Clinical and Experimental Endocrinology (Division)
Member
From1 Aug 2010 → 30 Sep 2022
Projects
1 - 8 of 8
- Metabolic dysfunction of skeletal cells during bone pathologyFrom11 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Linking metabolic alterations to skeletal cell dysfunction during bone pathologyFrom1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Linking metabolic alterations to skeletal cell dysfunction during bone pathologyFrom1 Oct 2022 → TodayFunding: BOF - projects
- The impact of bariatric surgery on bone, sex steroid status, inflammation and gut permeabilityFrom22 Sep 2020 → 16 Jul 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Metabolic fate of glucose in osteolineage cells in normal conditions and hyperglycemia.From1 Jan 2020 → TodayFunding: FWO research project
- Glutamine metabolism in healthy and osteoarthritic cartilageFrom1 Oct 2019 → 30 Sep 2022Funding: FWO fellowships
- Glutamine metabolism in osteocytes during bone homeostasis and pathologyFrom1 Oct 2016 → 30 Sep 2019Funding: FWO fellowships
- Skeletal cell metabolism and bone regenerationFrom1 Oct 2016 → 31 Mar 2022Funding: FWO Strategic Basic Research Grant, BOF - Doctoral projects
Publications
1 - 10 of 28
- Amino acid metabolism in skeletal cells(2022)
Authors: Claire-Sophie Devignes, Gertrudis Carmeliet, Steve Stegen
- Isolation and in vitro characterization of murine young-adult long bone skeletal progenitors(2022)
Authors: Shauni Loopmans, Gertrudis Carmeliet, Steve Stegen
- Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle(2022)
Authors: Shauni Loopmans, Steve Stegen, Guy Eelen, Peter Carmeliet, Bart Ghesquière, Bernard Thienpont, Sarah-Maria Fendt, Gertrudis Carmeliet
- The Combination of the CDK4/6 Inhibitor, Palbociclib, With the Vitamin D-3 Analog, Inecalcitol, Has Potent In Vitro and In Vivo Anticancer Effects in Hormone-Sensitive Breast Cancer, But Has a More Limited Effect in Triple-Negative Breast Cancer(2022)
Authors: Justine Vanhevel, Lieve Verlinden, Shauni Loopmans, Stefanie Doms, Steve Stegen, Hans Wildiers, Annemieke Verstuyf
- Glutamine Metabolism in Osteoprogenitors Is Required for Bone Mass Accrual and PTH-Induced Bone Anabolism in Male Mice(2020)
Authors: Steve Stegen, Claire-Sophie Devignes, Peter Carmeliet, Gertrudis Carmeliet
Pages: 604 - 616 - Glutamine Metabolism Controls Chondrocyte Identity and Function(2020)
Authors: Steve Stegen, Gianmarco Rinaldi, Shauni Loopmans, Bernard Thienpont, Sarah-Maria Fendt, Peter Carmeliet, Gertrudis Carmeliet
Pages: 530 - + - Single-cell RNA sequencing maps endothelial metabolic plasticity in pathological angiogenesis(2020)
Authors: Katerina Rohlenova, Melissa García Caballero, Lucas Treps, Laura De Rooij, Liliana Sokol, Laure-Anne Teuwen, Vincent Geldhof, Federico Taverna, Steve Stegen, Dena Panovska, et al.
Pages: 862 - 877 - Nestin-GFP transgene labels skeletal progenitors in the periosteum(2020)
Authors: Guillaume Tournaire, Steve Stegen, Greta Giacomini, Gertrudis Carmeliet
- Lipid availability determines fate of skeletal progenitor cells via SOX9(2020)
Authors: Steve Stegen, Guy Eelen, Aurélie Carlier, Patrizia Agostinis, Diether Lambrechts, Frederik Maes, Johannes Swinnen, Liesbet Geris, Hans Van Oosterwyck, Bernard Thienpont, et al.
Pages: 111 - + - Hypoxia, hypoxia-inducible transcription factors and oxygen-sensing prolyl hydroxylases in bone development and homeostasis(2019)
Authors: Steve Stegen, Gertrudis Carmeliet
Pages: 328 - 335