Researcher
Susan Schlenner
- Disciplines:Systems biology, Molecular and cell biology, Immunology
Affiliations
- Adaptive Immunology (Lab)
Responsible
From1 Jan 2019 → Today - Adaptive Immunology (Lab)
Member
From1 May 2012 → 30 Sep 2022
Infrastructure
1 - 1 of 1
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometry (Consortium coordinator)
Projects
1 - 10 of 26
- Validation of CCR8 agonism as therapeutic strategy for treatment of (auto-)inflammationFrom1 Mar 2024 → TodayFunding: IOF - technology validation in lab
- To be determinedFrom30 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The Functional Characterization of Immune Cells-Astrocyte Interactions during CNS InflammationFrom16 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Study the function of short Psi in mouse and human immune cellsFrom1 May 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Functional dissection of RNA modifiers in immune cells using CROPseqFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Role of RNA modification in immune cell functionFrom1 Oct 2021 → TodayFunding: FWO fellowships
- Spectral flowcytometry (Cytek Aurora)From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- ”RNA modifications: new mechanisms to regulate immune homeostasis and function”From1 Oct 2020 → TodayFunding: BOF - projects
Publications
11 - 20 of 44
- Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop(2022)
Authors: Yichao Hua, Gerlanda Vella, Ann Smeets, David Nittner, Francesca Bosisio, Beppe Floris, Diether Lambrechts, Chris Marine, Susan Schlenner, Gabriele Bergers
Pages: 1600 - + - Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits (vol 219, e2021239107142022cpg , 2022)(2022)
Authors: Susan Schlenner, Adrian Liston
- Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits(2022)
Authors: Susan Schlenner, James Dooley, Adrian Liston
- Unstable regulatory T cells, enriched for naive and Nrp1neg cells, are purged after fate challenge(2021)
Authors: Steffie Junius, Pierre Lemaitre, Margaux Gerbaux, Frederik Staels, Jeroen Raes, Stephanie Humblet-Baron, Adrian Liston, Susan Schlenner
- Functional dissection of regulatory T cell plasticity and stability(2021)
Authors: Steffie Junius, Susan Schlenner, Adrian Liston
- Defective Sec61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia(2020)
Authors: Erika Van Nieuwenhove, Julika Neumann, Elien Smeets, Emanuela Pasciuto, Vasiliki Lagou, Laura Seldeslachts, Bert Malengier-Devlies, Mieke Metzemaekers, Rob van der Kant, Joost Schymkowitz, et al.
Pages: 1180 - 1193 - Necroptosis in Immuno-Oncology and Cancer Immunotherapy(2020)
Authors: Jenny Sprooten, Isaure Vanmeerbeek, Peter Vangheluwe, Susan Schlenner, Jan Parys, Geert Bultynck, Abhishek Garg
- The phosphatase regulator NIPP1 restrains chemokine-driven skin inflammation.(2020)
Authors: Iris Verbinnen, Marloes Jonkhout, Kathelijne Szekér, Margareta Nikolic, Susan Schlenner, Aleyde Van Eynde, Mathieu Bollen
Pages: 1576 - 1588 - NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology(2019)
Authors: Susan Schlenner, Emanuela Pasciuto, Vasiliki Lagou, Steffie Junius, James Dooley, Erika Van Nieuwenhove, Stephanie Humblet-Baron, Carine Wouters, Adrian Liston
Pages: 342 - 349 - A robust pipeline with high replication rate for detection of somatic variants in the adaptive immune system as a source of common genetic variation in autoimmune disease.(2018)
Authors: Lies Van Horebeek, Susan Schlenner, Adrian Liston, Bénédicte Dubois, An Goris
Pages: 1369 - 1380