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Researcher

Tamara Vanhaecke

  • Research Expertise:

    Basic research related to the development of in vitro alternative methods:

    • Human liver-based in vitro models
    • Adult human skin-derived progenitor cells and their hepatic derivatives
    • DILI screening, including steatosis, phospholipidosis and acute liver failure
    • Flow cytometry-based high throughput screening of various hepatic cell models, for live/dead cell analysis, lipid and phospholipid accumulation
    • Microscopy-based high content analysis for lipid and mitochondrial deregulation analysis
    • Genotoxicant-specific qPCR array
    • Transcriptomics and metabolomics readouts and analysis
    • Risk assessment of consumer products
  • Keywords:Pharmacy and pharmacology
  • Disciplines:Toxicogenomics, Gene and molecular therapy, Hepatology, Cell, tissue and organ engineering, In vitro testing, Biomarker discovery, Compound screening, Stem cell biology
  • Users of research expertise:

    Basic research related to the development of in vitro alternative methods:

    • Human liver-based in vitro models
    • Adult human skin-derived progenitor cells and their hepatic derivatives
    • DILI screening, including steatosis, phospholipidosis and acute liver failure
    • Flow cytometry-based high throughput screening of various hepatic cell models, for live/dead cell analysis, lipid and phospholipid accumulation
    • Microscopy-based high content analysis for lipid and mitochondrial deregulation analysis
    • Genotoxicant-specific qPCR array
    • Transcriptomics and metabolomics readouts and analysis
    • Risk assessment of consumer products