Researcher
Tim Lammens
- Keywords:acute myeloid leukemi, inherited predisposition for cancer, asparaginase, neuroblastoma, juvenile myelomonocytic leukemia, pediatric oncology
- Disciplines:Molecular and cell biology not elsewhere classified, Oncology not elsewhere classified, Genomics, Pediatrics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Jun 2009 → 30 Sep 2018 - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Oct 2004 → 31 Jan 2009
Projects
1 - 10 of 11
- Preclinical validation of a less toxic variant for paediatric leukemiaFrom1 Oct 2022 → TodayFunding: Nonprofit institution or equivalents
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- The impact of magnetic particulate matter (mPM) pollution as a contributing factor for development of childhood cancer: an in vitro and in vivo molecular and cellular analysis.From1 Nov 2021 → 31 Oct 2022Funding: Nonprofit institution or equivalents
- The use of a less toxic alternative asparaginase variant to treat metastatic breast cancerFrom1 Oct 2021 → TodayFunding: BOF - projects
- Preclinical study of TARP-directed cellular and nanobody therapy in pediatric AML: improving survival and quality-of-lifeFrom1 Nov 2020 → TodayFunding: Nonprofit institution or equivalents
- Minimal residual disease targeting in T-cell acute lymphoblastic leukemiaFrom1 Oct 2020 → 23 Sep 2022Funding: BOF - postdoctoral mandates
- Predisposition in a family with two pediatric patients with Hodgkin lymphoma Non-BurkettFrom1 Jun 2016 → 31 May 2018Funding: Foundations, funds and other with scientific goal
- Research Assignment dr. Tim Lammens ihkv the ongoing clinical-translational research at the department of Pediatric Hematology-Oncology and Stem Cell TransplantationFrom1 Jun 2015 → 30 Sep 2019Funding: Nonprofit institution or equivalents
- Evaluation of the prognostic value of the leukemic stem cell (LSC) and pre-leukemic hematopoietic stem cell (pre-L HSC) for minimal residual disease monitoring and clinical management of pediatric acute myeloid leukemia patientsFrom1 Jan 2015 → 31 Dec 2018Funding: Foundations, funds and other with scientific goal
- The role of non-coding RNA in juvenile myelomonocytic leukemiaFrom1 Jan 2013 → 31 Dec 2015Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 118
- Predicting outcomes with circulating adrenergic neuroblastoma mRNAs in children with relapsed and refractory neuroblastoma : a BEACON-Neuroblastoma biomarker study(2022)Volume: 40
Authors: Lucas Moreno, Rebekah Weston, Virginie Viprey, Andrei Tchirkov, Maria Corrias, Tim Lammens, Juliet Gray, Cormac Owens, Jennifer Laidler, Marion Gambart, et al.
Number of pages: 1 - The feasibility of using liquid biopsies as a complementary assay for copy number aberration profiling in routinely collected paediatric cancer patient samples(2022)
Authors: Ruben Van Paemel, Charlotte Vandeputte, Lennart Raman, Jolien Van Thorre, Leen Willems, Jo Van Dorpe, Malaïka Van der Linden, Jilke De Wilde, Andries De Koker, Björn Menten, et al.
Pages: 12 - 23 - Targeted therapy in juvenile myelomonocytic leukemia : where are we now?(2022)
Authors: Nele De Vos, Mattias Hofmans, Tim Lammens, Bram De Wilde, Nadine Van Roy, Barbara De Moerloose
- A clinically annotated post-mortem approach to study multi-organ somatic mutational clonality in normal tissues(2022)
Authors: Tom Luijts, Kerryn Elliott, Joachim Siaw, Joris Van de Velde, Elien Beyls, Arne Claeys, Tim Lammens, Erik Larsson, Wouter Willaert, Anne Vral, et al.
- Evaluation of PEG-L-asparaginase in asparagine suppression and anti-drug antibody development in healthy Beagle dogs : a multi-phase preclinical study(2022)
Authors: L.R. Feenstra, R. Gehring, I.M. van Geijswijk, T. König, H.C.M.T Prinsen, Katrien Vandemeulebroecke, Tim Lammens, A. Krupa, E. Teske
- Tracking the molecular fingerprint of head and neck cancer for recurrence detection in liquid biopsies(2022)
Authors: Araceli Diez-Fraile, Joke De Ceulaer, Charlotte Derpoorter, Christophe Spaas, Tom De Backer, Philippe Lamoral, Johan Abeloos, Tim Lammens
- Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring(2021)
Authors: Araceli Diez-Fraile, Joke De Ceulaer, Charlotte Derpoorter, Christophe Spaas, Tom De Backer, Philippe Lamoral, Johan Abeloos, Tim Lammens
- Germline SAMD9L triple-allelic mosaicism with independent segregation into biallelic offsprings : molecular support for non-mendelian inheritance(2021)Volume: 8
Authors: S Sahoo, C Goodings, M Angeles Lillo, Tim Lammens, J van der Werff ten Bosch, B Strahm, Barbara De Moerloose, M Wlodarski
Number of pages: 1 - CircRNAs dysregulated in juvenile myelomonocytic leukemia : CircMCTP1 stands out(2021)
Authors: Anna Dal Molin, Mattias Hofmans, Enrico Gaffo, Alessia Buratin, Hélène Cavé, Christian Flotho, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Pieter Van Vlierberghe, et al.
- RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia(2021)
Authors: Filip Matthijssens, Nitesh D. Sharma, Monique Nysus, Christian K. Nickl, Huining Kang, Dominique R. Perez, Béatrice Lintermans, Wouter Van Loocke, Juliette Roels, Sofie Peirs, et al.