Researcher
Tim VANMIERLO
- Keywords:Biomedical sciences (incl. biochemistry)
- Disciplines:Cognitive neuroscience, Regenerative medicine not elsewhere classified
Affiliations
- Neurosciences (Department)
Member
From1 Jan 2020 → Today - Neurosciences (Research group)
Member
From1 Jan 2020 → Today - Biomedical Research Institute (Research institute)
Member
From1 Oct 2012 → Today - Faculty of Medicine and Life Sciences (Faculty)
Member
From1 Oct 2012 → Today - Physiology - Biochemistry - Immunology (Department)
Member
From1 Oct 2012 → 31 Dec 2019 - Immunology - Biochemistry (Research group)
Member
From1 Oct 2012 → 31 Dec 2019
Projects
11 - 20 of 34
- RICE to the next levelFrom16 Mar 2022 → 15 Mar 2023Funding: IOF - technology concept exploration
- Deep immune-phenotyping of multiple sclerosis patients using advanced spectral flow cytometryFrom1 Jan 2022 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- Preserving oligodendrocyte precursor cellsFrom1 Jan 2022 → 31 Dec 2023Funding: Foundations, funds and other with scientific goal
- Out-of-control microglia cause cognitive deficits through excessive synaptic elimination in Alzheimer's DiseaseFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Targeted PDE4 inhibition to counteract neuroinflammation: a stroke of genius.From1 Nov 2021 → TodayFunding: BOF - doctoral mandates
- Targeting phosphodiesterase 4D (PDE4D) isoforms, a novel approach to boost repair in multiple sclerosisFrom1 Feb 2021 → 31 May 2023Funding: FWO Strategic Basic Research Grant
- The epigenetic signature of myelin genes as innovative biomarker for progressive multiple sclerosisFrom1 Jan 2021 → 31 Mar 2023Funding: FWO Strategic Basic Research Grant
- Targeting microglia-mediated excessive synaptic elimination in Alzheimer's DiseaseFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- All you can EAAT3: restoring myelin, the brain's favourite fat.From1 Nov 2020 → 31 Oct 2022Funding: FWO Strategic Basic Research Grant
- Derisking Gebr-32aFrom1 Feb 2020 → 30 Jun 2023Funding: IOF - technology validation in lab
Publications
1 - 10 of 100
- Novel insights in phosphodiesterase 4 subtype inhibition to target neuroinflammation and stimulate remyelination(2024)
Authors: Melissa SCHEPERS, Tim VANMIERLO
Pages: 493 - 494 - The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis(2024)
Authors: Assia TIANE, Veerle SOMERS, Niels HELLINGS, DLA van den Hove, Tim VANMIERLO
- The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation(2024)
Authors: Emily WILLEMS, Melissa SCHEPERS, Elisabeth PICCART, Esther WOLFS, Niels HELLINGS, Maria Ait-Tihyaty, Tim VANMIERLO
- Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720(2023)
Authors: Alessandra Roggeri, Guendalina Olivero, Cesare Usai, Tim VANMIERLO, Anna Pittaluga
- Relieving the epigenetic blockade in progressive MS - making remyelination accessible again(2023)
Authors: Assia TIANE, Tim VANMIERLO
Number of pages: 214 - Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury(2023)
Authors: Femke Mussen, Jana VAN BROECKHOVEN, Niels HELLINGS, Melissa SCHEPERS, Tim VANMIERLO
- Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?(2023)
Authors: Ellis NELISSEN, Melissa SCHEPERS, Laura PONSAERTS, Sebastien Foulquier, Annelies BRONCKAERS, Tim VANMIERLO, Peter Sandner, Jos Prickaerts
- From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions(2023)
Authors: Assia TIANE, Melissa SCHEPERS, Rick A. Reijnders, Lieve VAN VEGGEL, Sarah CHENINE, Ben ROMBAUT, Emma Dempster, Catherine Verfaillie, Kobi Wasner, Anne Gruenewald, et al.
Pages: 283 - 299 - Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease?(2023)
Authors: Nikita MARTENS, Na ZHAN, Gardi Voortman, Frank P. J. Leijten, Connor van Rheenen, Suzanne van Leerdam, Xicheng Geng, Michiel HUYBRECHTS, Hongbing Liu, Johan W. W. Jonker, et al.
- Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases(2023)
Authors: Na ZHAN, Boyang Wang, Nikita MARTENS, Yankai Liu, Shangge Zhao, Gardi Voortman, Jeroen Van Rooij, Frank Leijten, Tim VANMIERLO, Folkert Kuipers, et al.
Patents
1 - 2 of 2