Researcher
Tom Desmet
- Keywords:biocatalysis, enzyme engineering, carbohydrate biotechnology
- Disciplines:Industrial molecular engineering of nucleic acids and proteins, Carbohydrates, Biocatalysis and enzyme technology
Affiliations
- Department of Biotechnology (Department)
Responsible
From1 Oct 2022 → Today - Department of Biotechnology (Department)
Member
From1 Oct 2022 → Today - Department of Biotechnology (Department)
Member
From1 Jan 2018 → Today - Department of Biochemical and microbial technology (Department)
Member
From1 Apr 2006 → 31 Dec 2017 - Department of Biochemistry and microbiology (Department)
Member
From1 Jan 2001 → 31 Mar 2006
Projects
1 - 10 of 32
- Oligosaccharide purification system – effective purification of short oligosaccharidesFrom20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- The quest for an aldose C3-epimerase: the missing link in sugar conversionsFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Guided by Nature: enzyme tunnel evolution as a tool for functional adaptationFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- Off the beaten path of protein evolution: insertions and deletions as drivers of functional innovationFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Rational design and synthesis of non-hallucinogenic psilocin analogues as selective 5-HT2A receptor agonists with therapeutic potentialFrom1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Radical-based Enzymatic Degradation of Organic Pollutants (REDOP)From1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Cofunding core facility - HTS for SynBioFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- MyCOS - Synthetic biology for a sustainable conversion of fungal chitin-rich waste streams into valuable biobased chitooligosaccharides for plant healthFrom1 Jan 2022 → 31 Dec 2023Funding: FWO Thematic call for research projects in the field of bioeconomy
- Evolution in practice: converting hydrolases and transferases into phosphorylasesFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Unlocking the specificity determinants in nucleotide sugar epimerasesFrom1 Nov 2021 → TodayFunding: FWO fellowships
Publications
11 - 20 of 34
- Stereo-electronic control of reaction selectivity in short-chain dehydrogenases : decarboxylation, epimerization, and dehydration(2021)
Authors: Annika J.E. Borg, Koen Beerens, Martin Pfeiffer, Tom Desmet, Bernd Nidetzky
Pages: 43 - 52 - Novel insights into the existence of the putative UDP-glucuronate 5-epimerase specificity(2020)
Authors: Ophelia Gevaert, Stevie Van Overtveldt, Matthieu Da Costa, Koen Beerens, Tom Desmet
- Engineering of cellobiose phosphorylase for the defined synthesis of cellotriose(2020)
Authors: Zorica Ubiparip, David Sáez Moreno, Koen Beerens, Tom Desmet
Pages: 8327 - 8337 - Sucrose phosphorylase and related enzymes in glycoside hydrolase family 13 : discovery, application and engineering(2020)
Authors: Jorick Franceus, Tom Desmet
- Effects of thymol and thymol α-D-Glucopyranoside on intestinal function and microbiota of weaned pigs(2020)
Authors: Noémie Van Noten, Jeroen Degroote, Elout Van Liefferinge, Bernard Taminiau, Stefaan De Smet, Tom Desmet, Joris Michiels
- Structural features on the substrate-binding surface of fungal lytic polysaccharide monooxygenases determine their oxidative regioselectivity(2019)
Authors: Barbara Danneels, Magali Tanghe, Tom Desmet
- Structural comparison of a promiscuous and a highly specific sucrose 6F-phosphate phosphorylase(2019)
Authors: Jorick Franceus, Nikolas Capra, Tom Desmet, Andy-Mark W.H. Thunnissen
- Discovery of novel cellodextrin phosphorylases : where bioinformatics meets biochemistry(2019)
Authors: Zorica Ubiparip, Jorick Franceus, Nídia Martins, Koen Beerens, Tom Desmet
Number of pages: 1 - Converting galactose into the rare sugar talose with cellobiose 2-epimerase as biocatalyst(2018)
Authors: Stevie Van Overtveldt, Ophelia Gevaert, Martijn Cherlet, Koen Beerens, Tom Desmet
- Analysis of the substrate specificity of α-L-arabinofuranosidases by DNA sequencer-aided fluorophore-assisted carbohydrate electrophoresis(2018)
Authors: Maria João de Carvalho Maurício da Fonseca, Edita Jurak, Kim Kataja, Emma R Master, Jean-Guy Berrin, Ingeborg Stals, Tom Desmet, Anita Van Landschoot, Yves Briers
Pages: 10091 - 10102
Patents
1 - 6 of 6
- Mutant sucrose phosphorylases with improved glycosylation activity towards polyphenols (Inventor)
- A sucrose phosphorylase for the production of kojibiose (Inventor)
- Mutant sucrose phosphorylases with improved glycosylation activity towards polyphenols (Inventor)
- A sucrose phosphorylase for the production of kojibiose (Inventor)
- Mutant sucrose synthases and their uses (Inventor)
- System for adaptive drug delivery (Inventor)